DNA supercoiling changes and nucleoid protein composition in a group of L5178Y cells of varying radiosensitivity

Radiation Research

Volumn 145, Issue 2, 1996, Pages 239-242

  Malyapa, Robert S ^a   Wright, William D ^a   Roti Roti, Joseph L ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR PROTEIN;

ARTICLE; CELL NUCLEUS MATRIX; DNA DAMAGE; DNA STRUCTURE; DNA SUPERCOILING; PRIORITY JOURNAL; PROTEIN ANALYSIS; RADIATION DOSE; RADIOSENSITIVITY;

ANIMALS; CHROMATIN; DNA REPAIR; DNA, NEOPLASM; DNA, SUPERHELICAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; LEUKEMIA L5178; MICE; NUCLEAR PROTEINS; TUMOR CELLS, CULTURED;

EID: 0030024907     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579181     Document Type: Article

References (21)

1. S. Okada, DNA as a target molecule responsible for cell killing. In Radiation Biochemistry (K. I. Altman, G. B. Gerber and S. Okada. Eds.), pp. 103-147. Academic Press, New York, 1970.
2. R. A. Phillips and L. J. Tolmach, Repair of potentially lethal damage in X-irradiated HeLa cells. Radiat. Res. 29, 413-432 (1966).
3. G. Iliakis, The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells. BioEssays 13, 641-648 (1991).
4. P. L. Olive, J. Hilton and R. E. Durand, DNA conformation of Chinese hamster V79 cells and sensitivity to ionizing radiation. Radiat. Res. 107, 115-124 (1986).
5. P. R. Cook and I. A. Brazell, Supercoils in human DNA. J. Cell Sci. 19, 261-279 (1976).
6. K. J. Pienta and D. S. Coffey, A structural analysis of the role of nuclear matrix and DNA loops in the organization of the nucleus and chromosome. J. Cell Sci. Suppl. 1, 123-153 (1984).
7. J. H. Shaper, D. M. Pardoll, S. H. Kaufmann, E. R. Barrack, B. Vogelstein and D. S. Coffey, The relationship of the nuclear matrix to cell structure and function. Adv. Enzyme Regul. 17, 213-221 (1978).
8. H. M. W. van der Velden and F. Wanka, The nuclear matrix - Its role in the spatial organization and replication of eukaryotic DNA. Mol. Biol Rep. 12, 69-77 (1987).
9. M. Kapiszewska, W. D. Wright, C. S. Lange and J. L. Roti Roti, DNA supercoiling changes in nucleoids from irradiated L5178Y-S and -R cells. Radiat. Res. 119, 569-575 (1989).
10. M. Kapiszewska, I. Szumiel and C. S. Lange, Damage at two levels of DNA folding measured by fluorescent halo technique in X-irradiated L5178Y-R and L5178Y-S cells. I. Initial lesions. Radiat. Environ. Biophys. 31, 311-322 (1992).
11. M. Kapiszewska, I. Szumiel and C. S. Lange, Damage at two levels of DNA folding measured by fluorescent halo technique in X-irradiated L5178Y-R and L5178Y-S cells. II. Repair. Radiat. Environ. Biophys. 33, 35-44 (1994).
12. R. S. Malyapa, W. D. Wright and J. L. Roti Roti, Radiation sensitivity correlates with changes in DNA supercoiling and nucleoid protein content in cells of three Chinese hamster cell lines. Radiat. Res. 140, 312-320 (1994).
13. H. H. Evans, M. Ricanati and M. F. Horng, Deficiency in DNA repair in mouse lyphoma strain L5178Y-S. Proc. Natl. Acad. Sci. USA 84, 7562-7566 (1987).
14. K. Sato and N. Hieda, Isolation and characterization of a mutant mouse lymphoma cell sensitive to methyl methanesulfonate and X rays. Radiat. Res. 78, 167-171 (1979).
15. K. Sato, N. Hieda-Shiomi and H. Hama-Inaba, X-ray sensitive mutant mouse cells with various sensitivities to chemical mutagens. Mutat. Res. 121, 281-285 (1983).
16. M. A. Stackhouse, J. B. Oritz, K. Sato and D. J. Chen, Functional complementation of the radiation-sensitive mutant M10 cell line by human chromosome 5. Mutat. Res. 323, 47-52 (1994).
17. P. N. Dean and J. H. Jett, Mathematical analysis of DNA distributions derived from flow microfluorometry. J. Cell Biol. 60, 523-527 (1974).
18. P. Alexander and Z. B. Mikulski, Mouse lymphoma cells with different radiosensitivities. Nature 192, 572-573 (1961).
19. J. L. Roti Roti and W. D. Wright, Visualization of DNA loops in nucleoids from HeLa cells: assays for DNA damage and repair. Cytometry 8, 461-467 (1987).
20. M. G. Gerdes, K. C. Carter, P. T. Moen Jr. and J. B. Lawrence, Dynamic changes in the higher-order chromatin organization of specific sequences revealed by in situ hybridization of nuclear halos. J. Cell Biol. 126, 289-304 (1994).
21. K. Eguchi-Kasai, T. Kosaka, K. Sato and I. Kaneko, Reparability of DNA double-strand breaks and radiation sensitivity in five mammalian cell lines. Int. J. Radiat. Biol. 59, 97-104 (1991).