Processing of antibodies bound to B-cell lymphomas and lymphoblastoid cell lines

Cancer

Volumn 80, Issue 12 SUPPL., 1997, Pages 2425-2430

  Vangeepuram, Nita ^a   Ong, Gaik Lin ^a   Mattes, M Jules ^a  

^a CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY   (United States)

Author keywords

Antibodies; Antibody processing; B cell lymphomas; Immunotherapy

Indexed keywords

CD19 ANTIGEN; CD20 ANTIGEN; CD22 ANTIGEN; CD45 ANTIGEN; HLA ANTIGEN; MONOCLONAL ANTIBODY;

ANTIBODY AFFINITY; ANTIBODY PRODUCTION; B CELL LYMPHOMA; CONFERENCE PAPER; DISSOCIATION; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; ISOTOPE LABELING; LYMPHOBLASTOID CELL LINE; PRIORITY JOURNAL; PROTEIN PROCESSING;

EID: 2642593032     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0142(19971215)80:12+<2425::aid-cncr14>3.0.co;2-e     Document Type: Conference Paper

References (15)

1. Kyriakos RJ, Shih LB, Ong GL, Patel K, Goldenberg DM, Mattes MJ. The fate of antibodies bound to the surface of tumor cells in vitro. Cancer Res 1992;52:835-42.
2. Mattes MJ, Griffiths GL, Diril H, Goldenberg DM, Ong GL, Shih LB. Processing of antibody-radioisotope conjugates after binding to the surface of tumor cells. Cancer 1994;73: 787-93.
3. Shih LB, Thorpe SR, Griffiths GL, Diril H, Ong GL, Hansen HJ, et al. The processing and fate of antibodies and their radiolabels bound to the surface of tumor cells in vitro: a comparison of nine radiolabels. J Nucl Med 1994;35:899-908.
4. Hanna R, Ong GL, Mattes MJ. Processing of antibodies bound to B-cell lymphomas and other hematological malignancies. Cancer Res 1996;56:3062-8.
5. Jurcic JG, Scheinberg DA. Radioimmunotherapy of hematological cancer: problems and progress. Clin Cancer Res 1995; 1:1439-46.
6. Epstein AL, Levy R, Kin H, Henle W, Henle G, Kaplan HS. Biology of the human malignant lymphomas. IV. Functional characterization often histiocytic lymphoma cell lines. Cancer 1978;42:2379-91.
7. Schmid J, Möller P, Moldenhauer G, Dörken B, Bihl H, Matzku S. Monoclonal antibody uptake in B-cell lymphomas: experimental studies in nude mouse xenografts. Cancer Immunol Immunother 1993;36:274-80.
8. a blood group antigen is a marker for the M6 leukocyte activation antigen, the human homolog of OX-47 antigen, basigin and neurothelin, an immunoglobulin superfamily molecule that is widely expressed in human cells and tissues. Eur J Immunol 1997;27:891-7.
9. Harapanhalli RS, Schafranek W, Ong GL, Mattes MJ. Lysine-directed radioiodination of proteins with a cyanuric chloride derivative of aminofluorescein. Anal Biochem 1995;231:50-6.
10. Ong GL, Marria V, Mattes MJ. The fate of antibodies and their radiolabels bound to tumor cells in vitro: the effect of cross-linking at the cell surface and of anti-idiotype antibodies. Cancer Immunol Immunother 1994;39:325-31.
11. Press OW, Farr AG, Borroz KI, Anderson SK, Martin PJ. Endocytosis and degradation of monoclonal antibodies targeting human B-cell malignancies. Cancer Res 1989;49:4906-12.
12. Vervoordeldonk SF, Balkenende AY, van den Berg H, von dem Borne AEGKr, van der Schoot CE, Van Leeuwen EF, et al. Degradation of radioiodinated B cell monoclonal antibodies: inhibition via a FCγ-receptor-II-mediated mechanism and by drugs. Cancer Immunol Immunother 1996;42: 24-30.
13. Hansen HJ, Ong GL, Diril H, Valdez A, Roche PA, Griffiths GL, et al. Internalization and catabolism of radiolabeled antibodies to the MHC class-II invariant chain by B-cell lymphomas. Biochem J 1996;320:293-300.
14. Horwitz AF, Hatten ME, Burger MM. Membrane fatty acid replacements and their effect on growth and lectin-induced agglutinability. Proc Natl Acad Sd USA 1974;71:3115-9.
15. Press OW, Howell-Clark J, Anderson S, Bernstein I. Retention of B-cell-specific monoclonal antibodies by human lymphoma cells. Blood 1994;83:1390-7.