Penicillin and beyond: Evolution, protein fold, multimodular polypeptides, and multiprotein complexes

Microbial Drug Resistance

Volumn 2, Issue 2, 1996, Pages 163-175

  Ghuysen, Jean Marie ^a   Charlier, Paulette ^a   Coyette, Jacques ^a   Duez, Colette ^a   Fonzé, Eveline ^a   Fraipont, Claudine ^a   Goffin, Colette ^a   Joris, Bernard ^a   Nguyen Distèche, Martine ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMINO ACID; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; DIPEPTIDE; DRUG RECEPTOR; ERYTHROMYCIN; GLYCOPEPTIDE; GUANOSINE TRIPHOSPHATASE; HYDROLASE; LIGASE; MURAMIC ACID; N ACETYLGLUCOSAMINE; PENICILLIN BINDING PROTEIN; PENICILLIN DERIVATIVE; PEPTIDASE; PEPTIDOGLYCAN; PHOSPHATE; POLYPEPTIDE; PROTEIN; STREPTOMYCIN; TRANSFERASE; VANCOMYCIN;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL CELL WALL; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CROSS LINKING; GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SYNTHESIS;

EID: 0029996660     PISSN: 10766294     EISSN: None     Source Type: Journal    
DOI: 10.1089/mdr.1996.2.163     Document Type: Article

References (12)

1. Ayala, J.A., T. Garrido, M.A. de Pedro, and M. Vicente. 1994. Molecular biology of bacterial septation, pp. 73-101. In R. Hakenbeck and J.M. Ghuysen (eds.), New comprehensive biochemistry, Vol. 27, Bacterial cell wall. Elsevier Science Publishers, Amsterdam.
2. Basu, J., S. Mehapatra, M. Kundu, S. Mukhopadhyay, M. Nguyen-Distèche, P. Dubois, B. Joris, J. Van Beeumen, P. Chakrabarti, S.T. Cole, and J.M. Ghuysen. 1996. Identification and overexpression in Escherichia coli of a Mycobacterium leprae gene, pon1, encoding a high-molecular-mass class A penicillin-binding protein PBP1. J. Bacteriol. 178:1707-1711.
3. Berger-Bächi, B. 1994. Expression of resistance to methicillin. Trends Microbiol. 2:389-393.
4. Brown, E.D., E.I. Vivas, C.T. Walsh, and R. Kolter. 1995. MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli J. Bacteriol. 177:4194-4197.
5. Damblon, C., G.H. Zhao, M. Jamin, P. Ledent, A. Dubus, M. Vanhove, X. Raquet, L. Christiaens, and J. M. Frère. 1995. Breakdown of the stereospecificity of DD-peptidases and β-lactamases with thiolester substrates. Biochem. J. 309:431-436.
6. Dive, G., D. Dehareng, and J.M. Ghuysen. 1994. A detailed study of a molecule into a molecule: The N-acetyl-L-tryptophanamide in active site model of the d-chymotrypsin. J. Am. Chem. Soc. 116:2548-2556.
7. Dive, G., D. Dehareng, and D. Peeters. 1996. Proposition for the acylation mechanism of the serine proteases: A one-step process? Int. J. Quant. Chem. 58:85-107.
8. Dobson, C.M. 1995. Finding the right fold. Struct. Biol. 2:513-517.
9. Donachie, W.D. 1992. Regulation of the morphogenetic cycle of Escherichia coli, pp. 409-419. In M.A. de Pedro, J.V. Höltje, and W. Löffelhardt (eds.), Bacterial growth and Lysis: Metabolism and structure of the bacterial sacculus. Plenum Press, New York.
10. Dowson, C.G., T.J. Coffey, and B.G. Spratt. 1994. Origin and molecular epidemiology of penicillin-binding-protein-mediated resistance to β-lactam antibiotics. Trends Microbiol. 3:361-366.
11. El Kharroubi, A., P. Jacques, G. Piras, J. Coyette, J. Van Beeumen, and J.M. Ghuysen. 1991. The Enterococcus hirae R40 penicillin-binding protein 5 and the methicillin-resistant Slaphylococcus aureus penicillin-binding protein 2′ are homologs. Biochem. J. 280:463-469.
12. Englebert, S., G. Piras, A. El Kharroubi, B. Joris, J. Coyette, M. Nguyen-Distèche, and J.M. Ghuysen. 1993. Modular design of the bi(multi?)functional penicillin-binding proteins, pp. 319-333. In M.A. de Pedro, J.V. Höltje, and W. Löffelhardt (eds.), Bacterial growth and lysis: Metabolism and structure of the bacterial sacculus. Plenum Press, New York.