Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts

Biochemical Journal

Volumn 380, Issue 1, 2004, Pages 95-103

  Miyazaki, Koyomi ^a   Nagase, Takahiro ^b   Mesaki, Miho ^a   Narukawa, Junko ^a   Ohara, Osamu ^b,c   Ishida, Norio ^a,d  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b KAZUSA DNA RESEARCH INSTITUTE   (Japan)

^c RIKEN   (Japan)

^d TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Casein kinase I ; Circadian rhythm; Period; Phosphorylation; Proteasomal degradation

Indexed keywords

BIODEGRADATION; GENETIC ENGINEERING; PROTEINS; RNA;

PHOSPHORYLATION; SUBCELLULAR LOCALIZATION;

BIOCHEMISTRY;

CASEIN KINASE; CASEIN KINASE I; CASEIN KINASE IDELTA; CASEIN KINASE IEPSILON; CASEIN KINASE INHIBITOR; CRYPTOCHROME; LEPTOMYCIN B; MESSENGER RNA; N (2 AMINOETHYL) 5 CHLOROISOQUINOLINE 8 SULFONAMIDE; PER1 PROTEIN; PER2 PROTEIN; PERIOD 3 PROTEIN; PROTEASOME INHIBITOR; TRANSCRIPTION FACTOR CLOCK; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CIRCADIAN RHYTHM; FEEDBACK SYSTEM; FIBROBLAST; HUMAN; MOLECULAR WEIGHT; OSCILLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CASEIN KINASES; CELL CYCLE PROTEINS; CELLS, CULTURED; CIRCADIAN RHYTHM; CLONING, MOLECULAR; CULTURE MEDIA, SERUM-FREE; CYCLOHEXIMIDE; CYSTEINE ENDOPEPTIDASES; FATTY ACIDS, UNSATURATED; FIBROBLASTS; FLAVOPROTEINS; GENE EXPRESSION REGULATION; HUMANS; ISOQUINOLINES; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MULTIENZYME COMPLEXES; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 2642574991     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031308     Document Type: Article

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