Conformational screening of oligonucleotides by variable-temperature high performance liquid chromatography: Dissecting the duplex-hairpin-coil equilibria of d(CGCGAATTCGCG)

Biopolymers

Volumn 74, Issue 3, 2004, Pages 221-231

  Braunlin, William H ^a   Giri, Indrajit ^a   Beadling, Les ^a   Breslauer, Kenneth J ^b  

^a Transgenomic Inc   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Chromatographic separation; Nucleic acid structural transitions; Structure modulation duplex hairpin coil transitions; Variable temperature high performance liquid chromatography

Indexed keywords

ACETONITRILE; CONFORMATIONS; ENTHALPY; FREE ENERGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MELTING; SCREENING; SOLVENTS; SPECTROPHOTOMETERS;

CARTRIDGES; EQUILIBRIUM CONSTANTS; OLIGONUCLEOTIDES; STRUCTURAL TRANSITIONS;

NUCLEIC ACIDS;

ACETONITRILE; AMMONIUM ACETATE; OLIGONUCLEOTIDE;

ARTICLE; CONCENTRATION RESPONSE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEIC ACID STRUCTURE; SEPARATION TECHNIQUE; SPECTROSCOPY; STRUCTURE ANALYSIS; TEMPERATURE DEPENDENCE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; KINETICS; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; TEMPERATURE; THERMODYNAMICS;

EID: 2642573649     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.20079     Document Type: Article

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