The C-terminus of prenylin is important in forming a dimer conformation necessary for endoplasmic-reticulum-to-Golgi transport

Biochemical Journal

Volumn 380, Issue 1, 2004, Pages 43-49

  Liang, Zhimin ^a   Veeraprame, Helga ^a   Bayan, Nami ^a   Li, Guangpu ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Di acidic motif; Endoplasmic reticulum export (ER export); Prenylated Rab acceptor 1 (PRA1); Prenylin; Protein trafficking; Yip3

Indexed keywords

CONFORMATIONS; CROSSLINKING; DIMERS; MUTAGENESIS; PROTEINS;

ACIDIC RESIDUES; MUTANTS;

BIOCHEMISTRY;

ALANINE; AMINO ACID; DIMER; MEMBRANE PROTEIN; PRENYLIN; UNCLASSIFIED DRUG; VALINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIMERIZATION; ENDOPLASMIC RETICULUM; EXOCYTOSIS; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN FOLDING; PROTEIN FUNCTION; WILD TYPE;

AMINO ACID MOTIFS; ANIMALS; CELL LINE; CRICETINAE; CROSS-LINKING REAGENTS; DIMERIZATION; ENDOPLASMIC RETICULUM, SMOOTH; GOLGI APPARATUS; KIDNEY; MEMBRANE PROTEINS; MESOCRICETUS; MICE; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; VALINE;

EID: 2642532763     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031788     Document Type: Article

References (22)

1. Bucci, C., Chiariello, M., Lattero, D., Maiorano, M. and Bruni, C. B. (1999) Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1). Biochem. Biophys. Res. Commun. 258, 657-662
2. Figueroa, C., Taylor, J. and Vojtek, A. B. (2001 ) Prenylated Rab acceptor protein is a receptor for prenylated small GTPases. J. Biol. Chem. 276, 28219-28225
3. Liang, Z. and Li, G. (2000) Mouse prenylated Rab acceptor is a novel Golgi membrane protein. Biochem. Biophys. Res. Commun. 275, 509-516
4. Martincic, I., Peralta, M. E. and Ngsee, J. K. (1997) Isolation and characterization of a dual prenylated Rab and VAMP2 receptor. J. Biol. Chem. 272, 26991-26998
5. Abdul-Ghani, M., Gougeon, P. Y., Prasser, D. C., Da-Silva, L. F. and Ngsee, J. K. (2001) PRA isoforms are targeted to distinct membrane compartments. J. Biol. Chem. 276, 6225-6233
6. Sivars, U., Aivazian, D. and Pfeffer, S. R. (2003) Yip3 catalyses the dissociation of endosomal Rab-GDI complexes. Nature (London) 425, 856-859
7. Lin, J., Liang, Z., Zhang, Z. and Li, G. (2001) Membrane topography and topogenesis of prenylated Rab acceptor (PRA1). J. Biol. Chem. 276, 41733-41741
8. Wieland, F. T., Gleason, M. L., Serafini, T. A. and Rothman, J. E. (1987) The rate of bulk flow from the endoplasmic reticulum to the cell surface. Cell (Cambridge, Mass.) 50, 289-300
9. Miller, E. A., Beilharz, T. H., Malkus, P. N., Lee, M. C., Hamamoto, S., Orci, L. and Schekman, R. (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell (Cambridge, Mass.) 114, 497-509
10. Nishimura, N. and Balch, W. E. (1997) A di-acidic signal required for selective export from the endoplasmic reticulum. Science (Washington, D.C.) 277, 556-558
11. Sevier, C. S., Weisz, O. A., Davis, M. and Machamer, C. E. (2000) Efficient export of the vesicular stomatitis virus G protein from the endoplasmic reticulum requires a signal in the cytoplasmic tail that includes both tyrosine-based and di-acidic motifs. Mol. Biol. Cell 11, 13-22
12. Ma, D., Zerangue, N., Lin, Y. F., Collins, A., Yu, M., Jan, Y. N. and Jan, L. Y. (2001) Role of ER export signals in controlling surface potassium channel numbers. Science (Washington, D.C.) 291, 316-319
13. Warren, G. and Mellman, I. (1999) Bulk flow redux? Cell (Cambridge, Mass.) 98, 125-127
14. Hahn, C. S., Hahn, Y. S., Braciale, T. J. and Rice, C. M. (1992) Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc. Natl. Acad. Sci. U.S.A. 89, 2679-2683
15. Li, G. and Stahl, P. D. (1993) Structure-function relationship of the small GTPase Rab5. J. Biol. Chem. 268, 24475-24480
16. Anderson, D. J. and Blobel, G. (1983) Immunoprecipitations of proteins from cell-free translations. Methods Enzymol. 96, 111-120
17. Calero, M., Winand, N. J. and Collins, R. N. (2002) Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors. FEBS Lett. 515, 89-98
18. Barrowman, J., Wang, W., Zhang, Y. and Ferro-Novick, S. (2003) The Yip1p-Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles. J. Biol. Chem. 278, 19878-19884
19. Briley, G. P., Hissong, M. A., Chiu, M. L. and Lee, D. C. (1997) The carboxyl-terminal valine residues of proTGFα are required for its efficient maturation and intracellular routing. Mol. Biol. Cell 8, 1619-1631
20. Iodice, L., Sarnataro, S. and Bonatti, S. (2001 ) The carboxyl-terminal valine is required for transport of glycoprotein CD8α from the endoplasmic reticulum to the intermediate compartment. J. Biol. Chem. 276, 28920-28926
21. Nufer, O., Guldbrandsen, S., Degen, M., Kappeler, F., Paccaud, J. P., Tani, K. and Hauri, H. P. (2002) Role of cytoplasmic C-terminal amino acids of membrane proteins in ER export. J. Cell Sci. 115, 619-628
22. Gougeon, P. Y., Prosser, D. C., Da-Silva, L. F. and Ngsee, J. K. (2002) Disruption of Golgi morphology and trafficking in cells expressing mutant prenylated rab acceptor-1. J. Biol. Chem. 277, 36408-36414