The diagnostic and prognostic value of ECG-gated SPECT myocardial perfusion imaging

Journal of Nuclear Medicine

Volumn 45, Issue 5, 2004, Pages 912-921

  Go, Vanessa ^a   Bhatt, Mehul R ^a   Hendel, Robert C ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOBUTAMINE; TECHNETIUM 99M;

ANGIOCARDIOGRAPHY; BLOOD RHEOLOGY; CARDIOVASCULAR RISK; CORONARY ARTERY; CORONARY ARTERY DISEASE; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; ELECTROCARDIOGRAM; GATED IMAGING; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE PERFUSION; HEART SCINTISCANNING; HEART VENTRICLE HYPERTROPHY; HUMAN; ISCHEMIC HEART DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROGNOSIS; REVIEW; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TWO DIMENSIONAL ECHOCARDIOGRAPHY; ARTIFACT; CORONARY ARTERY BLOOD FLOW; ELECTROCARDIOGRAPHY; HEART; METHODOLOGY; PHYSIOLOGY; SCINTISCANNING;

ARTIFACTS; CORONARY CIRCULATION; CORONARY DISEASE; ELECTROCARDIOGRAPHY; GATED BLOOD-POOL IMAGING; HEART; HUMANS; PROGNOSIS; RISK ASSESSMENT; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; VENTRICULAR FUNCTION, LEFT;

EID: 2642523830     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (87)

1. Bateman TM, Berman DS, Heller GV, et al. American Society of Nuclear Cardiology position statement on electrocardiographic gating of myocardial perfusion SPECT scintigrams. J Nucl Cardiol. 1999;6:470-471.
2. Anonymous. Imaging guidelines for nuclear cardiology procedures. Part 2. American Society of Nuclear Cardiology. J Nucl Cardiol. 1999;6:G47-G84.
3. Hida S, Chikamori T, Usui Y, Yanagisawa H, Morishima T, Yamashina A. Effect of percutaneous coronary angioplasty on myocardial perfusion, function, and wall thickness as assessed by quantitative gated single-proton emission computed tomography. Am J Cardiol. 2003;91:591-594.
4. Germano G, Nichols K, Cullom SJ. Gated perfusion SPECT: technical considerations. In: DePuey EG, Garcia EV, Berman DS, eds. Cardiac SPECT Imaging. 2nd ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2001:103-115.
5. Cullom SJ, Case JA, Bateman TM. Electrocardiographically gated myocardial perfusion SPECT: technical principles and quality control considerations. J Nucl Cardiol. 1998;5:418-425.
6. Nichols K, Dorbala S, DePuey EG, Yao SS, Sharma A, Rozanski A. Influence of arrhythmias on gated SPECT myocardial perfusion and function quantification. J Nucl Med. 1999;40:924-934.
7. Hyun IY, Kwan J, Park KS, Lee WH. Reproducibility of Tl-201 and Tc-99m sestamibi gated myocardial perfusion SPECT measurement of myocardial function. J Nucl Cardiol. 2001;8:182-187.
8. Vellejo E, Chayo H, Plancarte G, Victoria D, Bialostozky D. Variability of serial same-day left ventricular ejection fraction using quantitative gated SPECT. J Nucl Cardiol. 2002;9:377-384.
9. Johnson LL, Verdesca SA, Aude WY, et al. Postischemic stunning can affect left ventricular ejection fraction and regional wall motion on post-stress gated sestamibi tomograms. J Am Coll Cardiol. 1997;30:1641-1648.
10. Germano G, Kiat H, Kavanagh PB, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med. 1995;36:2138-2147.
11. Germano G, Erel J, Lewin H, Kavanagh PB, Berman DS. Automatic quantitation of regional myocardial wall motion and thickening from gated technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography. J Am Coll Cardiol. 1997;30:1360-1367.
12. Nichols K, DePuey EG. Regional and global ventricular function analysis with SPECT perfusion imaging. In: Zaret BL, Beller GA, eds. Nuclear Cardiology: State of the Art and Future Directions. 2nd ed. St. Louis, MO: Mosby; 1999:216-234.
13. Vallejo E, Dione DP, Bruni WL, et al. Reproducibility and accuracy of gated SPECT for determination of left ventricular volumes and ejection fraction: experimental validation using MRI. J Nucl Med. 2000;41:874-882.
14. Vallejo E, Dione DP, Sinusas AJ, Wackers FJ. Assessment of left ventricular ejection fraction with quantitative gated SPECT: accuracy and correlation with first-pass radionuclide angiography. J Nucl Cardiol. 2000;7:461-470.
15. Nakajima K, Taki J, Higuchi T, et al. Gated SPECT quantification of small hearts: mathematical simulation and clinical application. Eur J Nucl Med. 2000;27:1372-1379.
16. Nichols K, Santana CA, Folks R, et al. Comparison between ECTb and QGS for assessment of left ventricular function from gated myocardial perfusion SPECT. J Nucl Cardiol. 2002;9:285-293.
17. Lum DP, Coel MN. Comparison of automatic quantification software for the measurement of ventricular volume and ejection fraction in gated myocardial perfusion SPECT. Nucl Med Commun. 2003;24:259-266.
18. Nakajima K, Higuchi T, Taki J, Kawano M, Tonami N. Accuracy of ventricular volume and ejection fraction measured by gated myocardial SPECT: comparison of 4 software programs. J Nucl Med. 2001;42:1571-1578.
19. 99mTc-sestamibi myocardial SPECT. J Nucl Med. 2001;42:695-700.
20. DePuey EG, Rozanski A. Using gated technetium-99m-sestamibi SPECT to characterize fixed myocardial defects as infarct or artifact. J Nucl Med. 1995;36:952-955.
21. Taillefer R, DePuey EG, Udelson JE, Beller GA, Latour Y, Reeves F. Comparative diagnostic accuracy of Tl-201 and Tc-99m sestamibi SPECT imaging (perfusion and ECG-gated SPECT) in detecting coronary artery disease in women. J Am Coll Cardiol. 1997;29:69-77.
22. Smanio PE, Watson DD, Segalla DL, Vinson EL, Smith WH, Beller GA. Value of gating of technetium-99m sestamibi single-photon emission computed tomographic imaging. J Am Coll Cardiol. 1997;30:1687-1692.
23. Chae SC, Heo J, Iskandrian AS, Wasserleben V, Cave V. Identification of extensive coronary artery disease in women by exercise single-photon emission computed tomographic (SPECT) thallium imaging. J Am Coll Cardiol. 1993;21:1305-1311.
24. Rehn T, Griffith LS, Achuff SC, et al. Exercise thallium-201 myocardial imaging in left main coronary artery disease: sensitive but not specific. Am J Cardiol. 1981;48:217-223.
25. Christian TF, Miller TD, Bailey KR, Gibbons RJ. Noninvasive identification of severe coronary artery disease using exercise tomographic thallium-201 imaging. Am J Cardiol. 1992;70:14-20.
26. Sharir T, Bacher-Stier C, Dhar S, et al. Identification of severe and extensive coronary artery disease by postexercise regional wall motion abnormalities in Tc-99m sestamibi gated single-photon emission computed tomography. Am J Cardiol. 2000;86:1171-1175.
27. Lima RS, Watson DD, Goode AR, et al. Incremental value of combined perfusion and function over perfusion alone by gated SPECT myocardial perfusion imaging for detection of severe three-vessel coronary artery disease. J Am Coll Cardiol. 2003;42:64-70.
28. 201Tl gated myocardial perfusion imaging. J Nucl Med. 2002;43:131-139.
29. Emmett L, Iwanochko RM, Freeman MR, Barolet A, Lee DS, Husain M. Reversible regional wall motion abnormalities on exercise technetium-99m-gated cardiac single photon emission computed tomography predict high-grade angiographic stenoses. J Am Coll Cardiol. 2002;39:991-998.
30. Kumita S, Cho K, Nakajo H, et al. Assessment of left ventricular diastolic function with electrography-gated myocardial perfusion SPECT: comparison with multigated equilibrium radionuclide angiography. J Nucl Cardiol. 2001;8:568-574.
31. Paul AK, Kusuoka H, Hasegawa T, Makikawa M, Nishimura T. Prolonged diastolic dysfunction following exercise induced ischaemia: a gated myocardial perfusion SPECT study. Nucl Med Commun. 2002;23:1129-1136.
32. Sharir T, Germano G, Kavanagh PB, et al. Incremental prognostic value of post-stress left ventricular ejection fraction and volume by gated myocardial perfusion single photon emission computed tomography. Circulation. 1999;100:1035-1042.
33. Sharir T, Germano G, Kang X, et al. Prediction of myocardial infarction versus cardiac death by gated myocardial perfusion SPECT: risk stratification by the amount of stress-induced ischemia and the poststress ejection fraction. J Nucl Med. 2001;42:831-837.
34. Kroll D, Farah W, McKendall GR, Reinert SE, Johnson LL. Prognostic value of stress-gated Tc-99m sestamibi SPECT after acute myocardial infarction. Am J Cardiol. 2001;87:381-386.
35. Hashimoto J, Suzuki T, Nakahara T, Kosuda S, Kubo A. Preoperative risk stratification using stress myocardial perfusion scintigraphy with electrocardiographic gating. J Nucl Med. 2003;44:385-390.
36. Danias PG, Ahlberg AW, Clark BA 3rd, et al. Combined assessment of myocardial perfusion and left ventricular function with exercise technetium-99m sestamibi gated single-photon emission computed tomography can differentiate between ischemic and nonischemic dilated cardiomyopathy. Am J Cardiol. 1998;82:1253-1258.
37. Inglese E, Brambilla M, Dondi M, et al. Assessment of myocardial viability after thallium-201 reinjection or rest-redistribution imaging: a multicenter study - the Italian Group of Nuclear Cardiology. J Nucl Med. 1995;36:555-563.
38. 18F-fluorodeoxyglucose. Circulation. 1991;83:26-37.
39. 99mTc-sestamibi. Circulation. 1994;89:2552-2561.
40. 201Tl imaging in detection of myocardial viability and prediction of improvement in left ventricular function after coronary bypass surgery in patients with severely depressed left ventricular function. Circulation. 1993;87:1630-1641.
41. Maes AF, Borgers M, Flameng W, et al. Assessment of myocardial viability in chronic coronary artery disease using technetium-99m sestamibi SPECT: correlation with histologic and positron emission tomographic studies and functional follow-up. J Am Coll Cardiol. 1997;29:62-68.
42. 201Tl in the presence of a severe coronary artery stenosis. Circulation. 1994;89:2332-2341.
43. Galassi AR, Centamore G, Fiscella A, et al. Comparison of rest-redistribution thallium-201 imaging and reinjection after stress-redistribution for the assessment of myocardial viability in patients with left ventricular dysfunction secondary to coronary artery disease. Am J Cardiol. 1995;75:436-442.
44. Dilsizian V, Smeltzer WR, Freedman NM, Dextras R, Bonow RO. Thallium reinjection after stress-redistribution imaging: does 24-hour delayed imaging after reinjection enhance detection of viable myocardium? Circulation. 1991;83:1247-1255.
45. Afridi I, Kleiman NS, Raizner AE, Zoghbi WA. Dobutamine echocardiography in myocardial hibernation: optimal dose and accuracy in predicting recovery of ventricular function after coronary angioplasty. Circulation. 1995;91:663-670.
46. Tamaki N, Yonekura Y, Yamashita K, et al. Positron emission tomography using fluorine-18 deoxyglucose in evaluation of coronary artery bypass grafting. Am J Cardiol. 1989;64:860-865.
47. Schelbert HR. Positron emission tomography for the assessment of myocardial viability. Circulation. 1991;84(3 suppl):I122-I131.
48. Gould KL. Clinical cardiac positron emission tomography: state of the art. Circulation. 1991;84(3 suppl):I22-I36.
49. Bax JJ, Wijns W, Cornel JH, Visser FC, Boersma E, Fioretti PM. Accuracy of currently available techniques for prediction of functional recovery after revascularization in patients with left ventricular dysfunction due to chronic coronary artery disease: comparison of pooled data. J Am Coll Cardiol. 1997;30:1451-1460.
50. Levine MG, McGill CC, Ahlberg AW, et al. Functional assessment with electrocardiographic gated single-photon emission computed tomography improves the ability of technetium-99m sestamibi myocardial perfusion imaging to predict myocardial viability in patients undergoing revascularization. Am J Cardiol. 1999;83:1-5.
51. Maruyama A, Hasegawa S, Paul AK, et al. Myocardial viability assessment with gated SPECT Tc-99m tetrofosmin % wall thickening: comparison with F-18 FDG-PET. Ann Nucl Med. 2002;16:25-32.
52. 99mTc-Tetrofosmin SPECT for prediction of functional recovery defined by MRI in patients with severe left ventricular dysfunction: additional value of gated SPECT. J Nucl Med. 1999;40:1824-1831.
53. Zafrir N, Vidne B, Sulkes J, Sclarovsky S. Usefulness of dobutamine radionuclide ventriculography for prediction of left ventricular function improvement after coronary artery bypass grafting for ischemic cardiomyopathy. Am J Cardiol. 1999;83:691-695.
54. 18F]fluorodeoxyglucose in patients with chronic coronary artery disease: a functional and morphological approach to the detection of residual myocardial viability. Circulation. 1995;91:1006-1015.
55. Leoncini M, Marcucci G, Sciagra R, et al. Prediction of functional recovery in patients with chronic coronary artery disease and left ventricular dysfunction combining the evaluation of myocardial perfusion and of contractile reserve using nitrate-enhanced technetium-99m sestamibi gated single-photon emission computed tomography and dobutamine stress. Am J Cardiol. 2001;87:1346-1350.
56. Leoncini M, Sciagra R, Maioli M, et al. Usefulness of dobutamine Tc-99m sestamibi-gated single-photon emission computed tomography for prediction of left ventricular ejection fraction outcome after coronary revascularization for ischemic cardiomyopathy. Am J Cardiol. 2002;89:817-821.
57. Yoshinaga K, Morita K, Yamada S, et al. Low-dose dobutamine electrocardiograph-gated myocardial SPECT for identifying viable myocardium: comparison with dobutamine stress echocardiography and PET. J Nucl Med. 2001;42:838-844.
58. Everaert H, Vanhove C, Franken P. Effects of low-dose dobutamine of left ventricular function in normal subjects as assessed by gated single-photon emission tomography myocardial perfusion studies. Eur J Nucl Med. 1999;26:1298-1303.
59. Leoncini M, Marcucci G, Sciagra R, et al. Comparison of baseline and low-dose dobutamine technetium-99m sestamibi scintigraphy with low-dose dobutamine echocardiography for predicting function recovery after revascularization. Am J Cardiol. 2000;86:153-157.
60. Nakajima K, Taki J, Kawano M, et al. Diastolic dysfunction in patients with systemic sclerosis detected by gated myocardial perfusion SPECT: an early sign of cardiac involvement. J Nucl Med. 2001;42:183-188.
61. Soudry G, Dibos PE. Gated myocardial perfusion scan leading to diagnosis of unsuspected massive pulmonary embolism [letter]. Ann Intern Med. 2000;132:845.
62. Ioannidis JP, Trikalinos TA, Danias PG. Electrocardiogram-gated single-photon emission computed tomography versus cardiac magnetic resonance imaging for the assessment of left ventricular volumes and ejection fraction: a meta-analysis. J Am Coll Cardiol. 2002;39:2059-2068.
63. Baba A, Hano T, Ohmori H, et al. Assessment of left ventricular function by thallium-201 quantitative gated cardiac SPECT. Kaku Igaku. 2002;39:21-27.
64. Itti E, Rosso J, Damien P, Auffret M, Thirion JP, Meignan M. Assessment of ejection fraction with Tl-201 gated SPECT in myocardial infarction: precision in a rest-redistribution study and accuracy versus planar angiography. J Nucl Cardiol. 2001;8:31-39.
65. Vourvouri EC, Poldermans D, Bax JJ, et al. Evaluation of left ventricular function and volumes in patients with ischaemic cardiomyopathy: gated single-photon emission computed tomography versus two-dimensional echocardiography. Eur J Nucl Med. 2001;28:1610-1615.
66. Higuchi T, Nakajima K, Taki J, Kinuya S, Bunko H, Tonami N. Assessment of left ventricular systolic and diastolic function based on the edge detection method with myocardial ECG-gated SPET. Eur J Nucl Med. 2001;28:1512-1516.
67. Faber TL, Cooke CD, Folks RD, et al. Left ventricular function and perfusion from gated SPECT perfusion images: an integrated method. J Nucl Med. 1999;40:650-659.
68. Tadamura E, Kudoh T, Motooka M, et al. Use of technetium-99m sestamibi ECG-gated single-photon emission tomography for the evaluation of left ventricular function following coronary artery bypass graft: comparison with three-dimensional magnetic resonance imaging. Eur J Nucl Med. 1999;26:705-712.
69. 99mTc-tetrofosmin myocardial SPECT. J Nucl Med. 1999;40:1693-1698.
70. Nichols K, Tamis J, DePuey EG, Mieres J, Malhotra S, Rozanski A. Relationship of gated SPECT ventricular function parameters to angiographic measurements. J Nucl Cardiol. 1998;5:295-303.
71. Nichols K, DePuey EG, Rozanski A, Salensky H, Friedman MI. Image enhancement of severely hypoperfused myocardia for computation of tomographic ejection fraction. J Nucl Med. 1997;38:1411-1417.
72. Atsma DE, Bavelaar-Croon CD, Germano G, et al. Good correlation between gated single photon emission computed myocardial tomography and contrast ventriculography in the assessment of global and regional left ventricular function. Int J Card Imaging. 2000;16:447-453.
73. Wright GA, McDade M, Keeble W, Martin W, Hutton I. Quantitative gated SPECT myocardial perfusion imaging with 201Tl: an assessment of the limitations. Nucl Med Commun. 2000;21:1147-1151.
74. Bax JJ, Lamb H, Dibbets P, et al. Comparison of gated single-photon emission computed tomography with magnetic resonance imaging for evaluation of left ventricular function in ischemic cardiomyopathy. Am J Cardiol. 2000;86:1299-1305.
75. Bavelaar-Croon CD, Kayser HW, van der Wall EE, et al. Left ventricular function: correlation of quantitative gated SPECT and MR imaging over a wide range of values. Radiology. 2000;217:572-575.
76. Cwajg E, Cwajg J, Keng F, He ZX, Nagueh S, Verani MS. Comparison of global and regional left ventricular function assessed by gated-SPECT and 2-D echo-cardiography. Rev Port Cardiol. 2000;19(suppl 1):I39-I46.
77. Nichols K, Lefkowitz D, Faber T, et al. Echocardiographic validation of gated SPECT ventricular function measurements. J Nucl Med. 2000;41:1308-1314.
78. He ZX, Cwajg E, Preslar JS, Mahmarian JJ, Verani MS. Accuracy of left ventricular ejection fraction determined by gated myocardial perfusion SPECT with Tl-201 and Tc-99m sestamibi: comparison with first-pass radionuclide angiography. J Nucl Cardiol. 1999;6:412-417.
79. Vaduganathan P, He ZX, Vick GW 3rd, Mahmarian JJ, Verani MS. Evaluation of left ventricular wall motion, volumes, and ejection fraction by gated myocardial tomography with technetium 99m-labeled tetrofosmin: a comparison with cine magnetic resonance imaging. J Nucl Cardiol. 1999;6:3-10.
80. 123I-BMIPP-gated SPECT. J Nucl Med. 1999;40:1840-1847.
81. Nichols K, DePuey EG, Rozanski A. Automation of gated tomographic left ventricular ejection fraction. J Nucl Cardiol. 1996;3:475-482.
82. Everaert H, Bossuyt A, Franken PR. Left ventricular ejection fraction and volumes from gated single photon emission tomographic myocardial perfusion images: comparison between two algorithms working in three-dimensional space. J Nucl Cardiol. 1997;4:472-476.
83. Chua T, Yin LC, Thiang TH, Choo TB, Ping DZ, Leng LY. Accuracy of the automated assessment of left ventricular function with gated perfusion SPECT in the presence of perfusion defects and left ventricular dysfunction: correlation with equilibrium radionuclide ventriculography and echocardiography. J Nucl Cardiol. 2000;7:301-311.
84. Abe M, Kazatani Y, Fukuda H, Tatsuno H, Habara H, Shinbata H. Left ventricular volumes, ejection fraction, and regional wall motion calculated with gated technetium-99m tetrofosmin SPECT in reperfused acute myocardial infarction at super-acute phase: comparison with left ventriculography. J Nucl Cardiol. 2000;7:569-574.
85. Manrique A, Koning R, Cribier A, Vera P. Effect of temporal sampling on evaluation of left ventricular ejection fraction by means of thallium-201 gated SPET: comparison of 16- and 8-interval gating, with reference to equilibrium radionuclide angiography. Eur J Nucl Med. 2000;27:694-699.
86. Williams KA, Taillon LA. Left ventricular function in patients with coronary artery disease assessed by gated tomographic myocardial perfusion images: comparison with assessment by contrast ventriculography and first-pass radionuclide angiography. J Am Coll Cardiol. 1996;27:173-181.
87. 99mTc-sestamibi myocardial perfusion gates SPECT. J Nucl Med. 2000;41:1445-1450.