Prolonged diastolic dysfunction following exercise induced ischaemia: a gated myocardial perfusion spect study

Nuclear Medicine Communications

Volumn 23, Issue 11, 2002, Pages 1129-1136

  Paul, A K ^a   Kusuoka, H ^a   Hasegawa, S ^a   Yonezawa, T ^a   Makikawa, M ^a   Nishimura, T ^a  

^a RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

Coronary artery disease; Diastolic function; Exercise induced ischaemia; Gated SPECT; Myocardial stunning

Indexed keywords

ARTICLE; CLINICAL TRIAL; CORONARY ARTERY ATHEROSCLEROSIS; EXERCISE TEST; FEMALE; GATED IMAGING; HEART LEFT VENTRICLE FUNCTION; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; REPRODUCIBILITY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; STUNNED HEART MUSCLE; ADULT; CALCULATION; CLINICAL PROTOCOL; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIASTOLE; DISEASE SEVERITY; EXERCISE; FOURIER TRANSFORMATION; HEART INFARCTION; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; INCIDENCE; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

CORONARY ARTERIOSCLEROSIS; EXERCISE TEST; FEMALE; GATED BLOOD-POOL IMAGING; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL STUNNING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; VENTRICULAR DYSFUNCTION, LEFT;

TETROFOSMIN TC 99M;

EID: 1842833930     PISSN: 01433636     EISSN: 14735628     Source Type: Journal    
DOI: 10.1097/00006231-200211000-00014     Document Type: Article

References (21)

1. Braunwald E, Kloner RA. The stunned myocardium: prolonged, postischaemic ventricular dysfunction. Circulation 1982; 66: 1146-1149.
2. Kloner RA, Bolli R, Marban E, et al. Medical and cellular implications of stunning, hibernation, and preconditioning: an NHLBI workshop. Circulation 1998; 97: 1848-1867.
3. Ambrosio G, Betocchi S, Pace L, et al. Prolonged impairment of regional contractile function after resolution of exercise-induced angina: evidence of myocardial stunning in patients with coronary artery disease. Circulation 1996; 94: 2455-2464.
4. Johnson LL, Verdesca SA, Aude WY, et al. Postischaemic stunning can affect left ventricular ejection fraction and regional wall motion on post-stress gated sestamibi tomograms. J Am Coll Cardiol 1997; 30: 1641-1648.
5. Paul AK, Hasegawa S, Yoshioka J, et al. Exercise-induced stunning continues for at least one hour: evaluation with quantitative gated single-photon emission tomography. Eur J Nucl Med 1999; 26: 410-415.
6. Charlat ML, O'Neill PG, Hartley CJ, Roberts R, Bolli R. Prolonged abnormalities of left ventricular diastolic wall thinning in the ‘stunned’ myocardium in conscious dogs: time course and relation to systolic function. J Am Coll Cardiol 1989; 13: 185-194.
7. Przyklenk K, Patel B, Kloner RA. Diastolic abnormalities of postischaemic ‘stunned’ myocardium. Am J Cardiol 1987; 60: 1211-1213.
8. Wijns W, Serruys PW, Slager CJ, et al. Effect of coronary occlusion during percutaneous transluminal angioplasty in human on left ventricular chamber stiffness and regional diastolic pressure-radius relations. J Am Coll Cardiol 1986; 7: 455-463.
9. Gimelli A, Marzullo P, Bartoli M, Sambuceti G, Giorgetti A, Parodi O. Ischaemia on effort is not a determinant of stunned myocardium in man: a radioisotopic study based on quantitative evaluation of ventricular dynamics. J Nucl Biol Med 1993; 37: 119-125.
10. Stoddard MF, Johnstone J, Dillon S, Kupersmith J. The effect of exercise-induced myocardial ischaemia on postischaemic left ventricular diastolic filling. Clin Cardiol 1992; 15: 265-273.
11. Fragasso G, Benti R, Sciammarella M, et al. Symptom-limited exercise-testing causes sustained diastolic dysfunction in patients with coronary disease and low effort tolerance. J Am Coll Cardiol 1991; 17: 1251-1255.
12. 99mTc-tetrofosmin myocardial SPET. Eur J Nucl Med 2001; 28: 593-601.
13. Kumita S, Cho K, Nakajo H, et al. Assessment of left ventricular diastolic function with electrocardiography-gated myocardial perfusion SPECT: comparison with multigated equilibrium radionuclide angiography. J Nucl Cardiol 2001; 8: 568-574.
14. Higuchi T, Nakajima K, Taki J, Kinuya S, Bunko H, Tonami N. Assessment of left ventricular systolic and diastolic function based on the edge detection method with myocardial ECG-gated SPET. Eur J Nucl Med 2001; 28: 1512-1516.
15. Germano G, Kiat H, Kavanagh PB, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med 1995; 36: 2138-2147.
16. 99mTc-teterofosmin myocardial SPECT. J Nucl Med 1999; 40: 1693-1698.
17. Paul AK, Hasegawa S, Yoshioka J, Yamaguchi H, Tsujimura E, Nishimura T. Assessment of left ventricular function by gated myocardial perfusion and gated blood-pool SPECT: can we use the same reference database? Ann Nucl Med 2000; 14: 75-80.
18. Massardo T, Gal RA, Grenier RP, Schmidt DH, Port SC. Left ventricular volume calculation using a count-based ratio method applied to multigated radionuclide angiography. J Nucl Med 1990; 31: 450-456.
19. Carrol JD, Hess OM, Hirzel HO, Krayenbuehl HP. Exercise-induced ischaemia: the influence of altered relaxation on early diastolic pressures. Circulation 1983; 67: 521-528.
20. 18F-fluorodeoxyglucose in postiscaemic myocardium of patients with exercise-induced angina. Circulation 1986; 74: 81-88.
21. Homans DC, Laxson DD, Sublett E, Lindstrom P, Bache RJ. Cumulative deterioration of myocardial function after repeated episodes of exercise-induced ischaemia. Am J Physiol 1989; 256: H1462-H1471.