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Singal P, Dixon I, Kirshenbaum LA, Dhalla N, (eds), Kluwer Academic Publishers, Boston: This is a thorough review of the past 20 years of pharmacologic treatment for heart failure, with an emphasis on how neurohormonally based therapy has supplanted therapy directed at hemodynamics. It also includes a discussion of the mechanisms of sympathoactivation heart failure
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Goldsmith SR: Therapeutics in congestive heart failure: from hemodynamics to neurohormones. In Cardiac Remodeling and Failure. Edited by Singal P, Dixon I, Kirshenbaum LA, Dhalla N. Boston: Kluwer Academic Publishers; 2003:17–34. This is a thorough review of the past 20 years of pharmacologic treatment for heart failure, with an emphasis on how neurohormonally based therapy has supplanted therapy directed at hemodynamics. It also includes a discussion of the mechanisms of sympathoactivation in heart failure.
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Improvement in symptoms and exercise tolerance by metoprolol in patients with dilated cardiomyopathy: a double-blind, randomized, placebo-controlled trial
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The renin-angiotensin-aldosterone system in chronic heart failure
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ATC, Secaucus, NY: This is a thorough review of the role of the RAAS heart failure, with therapeutic and mechanistic implications
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Cody RJ, Laragh JH: The renin-angiotensin-aldosterone system in chronic heart failure. In Drug Treatment of Heart Failure. Secaucus, NY: ATC; 1988:81. This is a thorough review of the role of the RAAS in heart failure, with therapeutic and mechanistic implications.
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Cody, R.J.1
Laragh, J.H.2
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0033995775
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Maximally recommended doses of angiotensin-converting enzyme (ACE) inhibitors do not completely prevent ACE-mediated formation of angiotensin II in chronic heart failure
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PID: 10694521, COI: 1:CAS:528:DC%2BD3cXhvVOgur0%3D
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Jorde UP, Ennezat PV, Lisker J, et al.: Maximally recommended doses of angiotensin-converting enzyme (ACE) inhibitors do not completely prevent ACE-mediated formation of angiotensin II in chronic heart failure. Circulation 2000, 101:844–846.
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Acute vasoconstrictor response to intravenous furosemide in patients with chronic congestive heart failure. Activation of the neurohumoral axis
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PID: 2860833, COI: 1:STN:280:DyaL2M3itlCrsA%3D%3D
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Francis GS, Siegel RM, Goldsmith SR, et al.: Acute vasoconstrictor response to intravenous furosemide in patients with chronic congestive heart failure. Activation of the neurohumoral axis. Ann Intern Med 1985, 103:1–6.
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Francis, G.S.1
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0035841607
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Beta-blockers, angiotensin II, and ACE inhibitors in patients with heart failure
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PID: 11716889, COI: 1:CAS:528:DC%2BD3MXosFKmtrg%3D, This is a good discussion of the interaction of the various neurohormonal systems clinical heart failure
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Campbell DJ, Aggarwal A, Esler M, Kaye D: Beta-blockers, angiotensin II, and ACE inhibitors in patients with heart failure. Lancet 2001, 358:1609–1610. This is a good discussion of the interaction of the various neurohormonal systems in clinical heart failure. DOI: 10.1016/S0140-6736(01)06660-0
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PID: 14608516, COI: 1:CAS:528:DC%2BD3sXpsFCmtrk%3D
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Cohn JN: Interaction of beta-blockers and angiotensin receptor blockers/ACE inhibitors in heart failure. J Renin Angiotensin Aldosterone Syst 2003, 4:137–139. DOI: 10.3317/jraas.2003.021
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PID: 12668699, COI: 1:CAS:528:DC%2BD3sXis1ehurY%3D
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Pitt B, Remme W, Zannad F, et al.: Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 2003, 348:1309–1321. DOI: 10.1056/NEJMoa030207
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Neural regulation of sympathetic nerve activity in heart failure
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PID: 7777669, COI: 1:STN:280:DyaK2M3ps1CrsA%3D%3D
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Zucker IH, Wang W, Brandle M, et al.: Neural regulation of sympathetic nerve activity in heart failure. Prog Cardiovasc Dis 1995, 37:397–414. DOI: 10.1016/S0033-0620(05)80020-9
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PID: 10404353, COI: 1:CAS:528:DyaK1MXksVOqs78%3D, This is a thorough review of the effects of angiotensin II on sympathetic activity, with an emphasis on clinical relevance to heart failure
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Goldsmith SR: Angiotensin II and sympathoactivation in heart failure. J Card Fail 1999, 5:139–145. This is a thorough review of the effects of angiotensin II on sympathetic activity, with an emphasis on clinical relevance to heart failure. DOI: 10.1016/S1071-9164(99)90036-2
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J Card Fail
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Cardiac sympathetic afferent reflex in dogs with congestive heart failure
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Prejunctional angiotensin II receptors. Facilitation of norepinephrine release in the human forearm
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PID: 8113403, COI: 1:CAS:528:DyaK2cXis1ahsL0%3D
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0025176862
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Subpressor infusions of angiotensin II do not stimulate sympathetic activity in humans
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PID: 2301607, COI: 1:CAS:528:DyaK3cXhtFars7o%3D
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Goldsmith SR, Hasking GJ: Subpressor infusions of angiotensin II do not stimulate sympathetic activity in humans. Am J Physiol 1990, 258:H179-H182.
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0027403518
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Angiotensin II and sympathetic nervous activity in patients with congestive heart failure
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PID: 8384645, COI: 1:STN:280:DyaK3s3htVansQ%3D%3D
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Goldsmith SR, Hasking GJ: Angiotensin II and sympathetic nervous activity in patients with congestive heart failure. J Am Coll Cardiol 1993, 21:1107–1113. DOI: 10.1016/0735-1097(93)90232-P
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Effect of angiotensin II on noradrenaline release in the human forearm
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PID: 8025910, COI: 1:CAS:528:DyaK2cXlslWgs7c%3D
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Goldsmith SR, Rector TS, Bank AJ, et al.: Effect of angiotensin II on noradrenaline release in the human forearm. Cardiovasc Res 1994, 28:663–666. DOI: 10.1093/cvr/28.5.663
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Goldsmith, S.R.1
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28
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Regulation of regional norepinephrine spillover in heart failure: the effect of angiotensin II and beta-adrenergic agonists in the forearm circulation
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PID: 9924852, COI: 1:CAS:528:DyaK1MXms1Kgug%3D%3D
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Goldsmith SR, Garr M, McLaurin M: Regulation of regional norepinephrine spillover in heart failure: the effect of angiotensin II and beta-adrenergic agonists in the forearm circulation. J Card Fail 1998, 4:305–310. DOI: 10.1016/S1071-9164(98)90236-6
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J Card Fail
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Goldsmith, S.R.1
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29
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0026026850
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Effect of a pressor infusion of angiotensin II on sympathetic activity and heart rate in normal humans
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PID: 1984867, COI: 1:CAS:528:DyaK3MXktVWksrY%3D
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Goldsmith SR, Hasking GJ: Effect of a pressor infusion of angiotensin II on sympathetic activity and heart rate in normal humans. Circ Res 1991, 68:263–268.
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Circ Res
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0031065432
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Angiotensin II enhances (ibid.) baroreflex control of sympathetic outflow in heart failure
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PID: 9040439, COI: 1:CAS:528:DyaK2sXhsFeltbw%3D
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Murakami H, Liu JL, Zucker IH: Angiotensin II enhances (ibid.) baroreflex control of sympathetic outflow in heart failure. Hypertension 1997, 29:564–569.
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0037454044
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Effect of spironolactone on cardiac sympathetic nerve activity and left ventricular remodeling in patients with dilated cardiomyopathy
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PID: 12598068, COI: 1:CAS:528:DC%2BD3sXitVKisLw%3D
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Kasama S, Toyama T, Kumakura H, et al.: Effect of spironolactone on cardiac sympathetic nerve activity and left ventricular remodeling in patients with dilated cardiomyopathy. J Am Coll Cardiol 2003, 41:574–581. DOI: 10.1016/S0735-1097(02)02855-3
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0030760332
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Effects of chronic ACE inhibition on sympathetic nerve traffic and baroreflex control of circulation in heart failure
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PID: 9286946, COI: 1:CAS:528:DyaK2sXlvVaqsrg%3D, This is perhaps the key paper linking therapy with ACEI to diminished activity of the sympathetic nervous system heart failure
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Grassi G, Cattaneo BM, Seravalle G, et al.: Effects of chronic ACE inhibition on sympathetic nerve traffic and baroreflex control of circulation in heart failure. Circulation 1997, 96:1173–1179. This is perhaps the key paper linking therapy with ACEI to diminished activity of the sympathetic nervous system in heart failure.
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Grassi, G.1
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33
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A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure
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PID: 2057035, COI: 1:STN:280:DyaK3M3nvV2gtg%3D%3D
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Cohn JN, Johnson G, Ziesche S, et al.: A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med 1991, 325:303–310. DOI: 10.1056/NEJM199108013250502
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0027167633
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Plasma norepinephrine, plasma renin activity, and congestive heart failure. Relations to survival and the effects of therapy in V-HeFT II. The V-HeFT VA Cooperative Studies Group
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PID: 8500238, COI: 1:STN:280:DyaK3s3nt1CgsQ%3D%3D, This is a provocative analysis linking differential outcomes of therapies the V-HEFT II trial to the effects of those therapies on plasma norepinephrine levels
-
Francis GS, Cohn JN, Johnson G, et al.: Plasma norepinephrine, plasma renin activity, and congestive heart failure. Relations to survival and the effects of therapy in V-HeFT II. The V-HeFT VA Cooperative Studies Group. Circulation 1993, 87:VI40-VI48. This is a provocative analysis linking differential outcomes of therapies in the V-HEFT II trial to the effects of those therapies on plasma norepinephrine levels.
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Circulation
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Francis, G.S.1
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Johnson, G.3
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