Novel enzymatic route for kinetic resolution of (±)1,4-benzodioxan- 2-carboxylic acid

Biochemical Engineering Journal

Volumn 27, Issue 1, 2005, Pages 66-71

  Kasture, Sangita M ^a   Varma, Rita ^a   Kalkote, Uttam R ^a   Nene, Sanjay ^a   Kulkarni, Bhaskar D ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

1,4 Benzodioxan 2 carboxylic acid; Doxazosin; Enantio selectivity; Enantiomeric ratio; Ethyl 1,4 benzodioxan 2 carboxylate; Ethyl acetate; Lipases; Transesterfication

Indexed keywords

DRUG PRODUCTS; ENZYME KINETICS; ENZYMES; ESTERIFICATION;

1,4-BENZODIOXAN-2-CARBOXYLATE; DOXAZOSIN; ENANTIO SELECTIVITY; ENANTIOMERIC RATIO; ETHYL 1,4-BENZODIOXAN-2-CARBOXYLIC ACID; ETHYL ACETATE; LIPASES; TRANSESTERIFICATION;

CARBOXYLIC ACIDS;

1,4 BENZODIOXAN DERIVATIVE; ACETIC ACID ETHYL ESTER; CARBOXYLIC ACID DERIVATIVE; TRIACYLGLYCEROL LIPASE;

ARTICLE; CANDIDA ANTARCTICA; CATALYSIS; CHEMICAL REACTION; ENANTIOMER; ENANTIOSELECTIVITY; ENZYME CHEMISTRY; KINETICS; PRIORITY JOURNAL; TRANSESTERIFICATION;

CANDIDA;

EID: 26044437897     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2005.06.014     Document Type: Article

References (15)

1. A report in Chemical weekly, August 18/25 (2004) 37.
2. R.M. Guthrie, and R.L. Siegel Clin. Ther. 21 1999 1732
3. S.F. Campbell, M.J. Davey, J.D. Hardstone, B.N. Lewis, and M.J. Palmer J. Med. Chem. 30 1987 49
4. C.H. Wong, and G.M. Whitesides J.E. Baldwin Enzymes in Synthesis of Organic Chemistry: Tetrahedron Organic Chemistry Series vol. 12 1994 Pergamon Press New York
5. K. Faber Biotransformations in Organic Chemistry second ed. 1995 Springer Verlag New York
6. M. Reetz, and K. Schimossek Chimia 50 1996 668
7. W.-C. Chou, C.-W. Tam, S.F. Chen, and H. Ku J. Org. Chem. 63 1998 10015
8. G. Kumarswamy, A.K. Das, J. Nivedita, Organic Preparations and Procedures International, Inc. 35 (2003) 603.
9. K.Q. Fang, P. Grover, Z. Han, F.X. McConville, R.F. Rossi, D.J. Olsson, D.W. Kessler, S.A. Wald, and C.H. Senanayake Tetrahedron: Asymmetry 12 2001 2169
10. M. Kordel, B. Hofman, D. Schomburg, and R.D. Schmid J. Bacteriol. 173 1991 4836
11. C.-S. Chen, Y. Fujimoto, G. Girdaukas, and C.J. Sih J. Am. Chem. Soc. 104 1982 7294
12. J.L.L. Rakels, A.J.J. Straathof, and J.J. Heijnen Enzyme Microb. Technol. 15 1993 1051
13. S. Antus, A. Gotteegen, J. Kajtar, T. Kovacs, T.S. Toth, and H. Wagner Tetrahydron: Asymmetry 4 1993 339
14. Y. Lu, X. Zhao, and Z.-N. Chen Tetrahydron: Asymmetry 6 1995 1093
15. R.A. Sheldon Chirotechnology: Industrial Synthesis of Optically Active Compound 1993 Marcel Dekker, Inc. New York