One-pot neat reactions of carboxylic esters and alkylenediamines for efficient preparation of N-acylalkylenediamines

Journal of Organic Chemistry

Volumn 63, Issue 26, 1998, Pages 10015-10017

  Chou, Wen Chih ^a   Tan, Chang Wei ^a   Chen, Shyh Fong ^a   Ku, Hao ^a  

^a DEVELOPMENT CENTER FOR BIOTECHNOLOGY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALFUZOSIN; ALIPHATIC AMINE; ANTIHYPERTENSIVE AGENT; BUNAZOSIN; DOXAZOSIN; ESTER; METAZOSIN; N ACYLALKYLENEDIAMINE DERIVATIVE; NELDAZOSIN; PRAZOSIN; TERAZOSIN; UNCLASSIFIED DRUG;

AMIDATION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; HYPERTENSION; SYNTHESIS;

EID: 0032567392     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo980830j     Document Type: Article

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42. For an actual application, the extract was concentrated and used in the subsequent coupling reaction for preparation to give Doxazosin. The U.S and R.O.C. patent applications are under review.