Methylation status of RARβ gene promoter in low and high grade cerebral glioma. Comparison with normal tissue. Immuno-histochemical study of nuclear RARβ expression in low and high grade cerebral glioma cells. Comparison with normal cells. 48 Tumors;Statut de méthylation du promoteur du gène RARb dans les tumeurs cérébrales gliales de bas et de haut grade. Comparaison avec le tissu sain. Étude immuno-histochimique du marquage au RARβ des noyaux des cellules tumorales dans les gliomes de bas et de haut grade. Comparaison avec les cellules saines, à propos de 48 tumeurs

Neurochirurgie

Volumn 51, Issue 3-4 I, 2005, Pages 147-154

  Klein, O ^a   Grignon, Y ^a   Civit, T ^a   Auque, J ^a   Marchal, J C ^a  

^a UNIVERSITY HOSPITAL OF NANCY   (France)

Author keywords

Glioblastoma; M thylation; Oligodendroglioma; Retinoic acid receptors; Retinoids

Indexed keywords

ALITRETINOIN; CELL NUCLEUS RECEPTOR; DNA; RETINOIC ACID RECEPTOR BETA; RETINOL;

ARTICLE; CANCER GRADING; CELL NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; GLIOBLASTOMA; GLIOMA; GLIOMA CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NORTHERN BLOTTING; OLIGODENDROGLIOMA; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN METHYLATION;

EID: 25844528123     PISSN: 00283770     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0028-3770(05)83470-8     Document Type: Article

References (31)

1. e ed. Paris: Flammarion Médecine-Sciences, 1990.
2. ALLENBY G, BOCQUEL MT, SA;UNDERS M, KAZMER S, SPECK J, ROSENBERGER M, et al. Retinoic acid receptors and retinoic X receptors: interactions with endogenous retinoic acids. Proc Natl: Acad Sci USA 1993; 90: 30-34.
3. ANDERSON AE, HAINES TR, ROBINSON DP, BUTCHER DT, SADIKOVIC B, RODENHISER DI. Sodium bisulfite analysis of the methylation status of DNA from small portions of paraffin slides. BioTechniques 2001; 31: 1004, 1006, 1008.
4. BAYLIN SB, HERMAN JG, GRAFF JR, VERTINO PM, ISSA JP. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res 1998; 72: 141-196.
5. BLANCHET S, MICHAILLE JJ. Les RXR ne sont pas des partenaires d'hétérodimérisation purement passifs. Med Sci 1998; 14: 1211-1216.
6. CARPENTIER AF, LEONARD M, LACOMBE J, ZASSADOWSKI F, PADUA RA, DEGOS L, et al. Retinoic acid modulate RAR alpha and RAR beta receptors in human glioma cell lines. Anticancer Res 1999; 19: 3189-3192.
7. CHAMBON P. A decade of molecular biology of retinoic acid receptors. FASEB J 1996; 10: 940-954.
8. CHEN ZX, XUE YQ, ZHANG R, TAO RF, XIA XM, LI C, et al. A clinical and experimental study on all-trans retinoic acid treated acute promyelocytic leukaemia patients. Blood 1991; 78: 1413-1419.
9. CHEUNG B, HOCKER JE, SMITH SA, NORRIS MD, HABER M, MARSHALL GM. Favorable prognostic significance of high-level retinoic acid receptor β expression in neuroblastoma mediated by effects on cell cycle regulation. Oncogene 1998; 17: 751-759.
10. CÔTE S, SINNETT D, MOMPARLER RL. Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells. Anticancer Drugs 1998; 9: 743-750.
11. DAUMAS-DUPORT C, SCHEITHAUER B, O'FALLON J, KELLY P. Grading of astrocytomas. A simple and reproducible method. Cancer 1988; 62: 2152-2165.
12. DIRKS PB, PATEL K, HUBBARD SL, ACKERLEY C, HAMEL PA, RUTKA JT. Retinoic acid and the cyclin dependent kinase inhibitors synergistically alter proliferation and morphology of U343 astrocytoma cells. Oncogene 1997; 15: 2037-2048.
13. DOLLE P, RUBERTE E, LEROY P, MORRISS-KAY G, CHAMBON P. Retinoic acid receptors and cellular retinoid binding proteins. I- A systematic study of their differential pattern of transcription during mouse organogenesis. Development 1990; 110: 1133-1151.
14. FUKUYAMA K, MATSUZAWA K, HUBBARD SL, DIRKS PB, MURAKAMI M, RUTKA JT. Analysis of glial fibrillary acidic protein gene methylation in human malignant gliomas. Anticancer Res 1996; 16: 1251-1257.
15. GIANNINI G, DAWSON MI, ZHANG X, THIELE CJ. Activation of three distinct RXR/RAR heterodimers induces growth arrest and differentiation of neuroblastoma cells. J Biol Chem 1997; 272: 26693-26701.
16. GIGUERE V. Retinoic acid receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling. Endocr Rev 1994; 15: 61-79.
17. HERMAN JG, GRAFF JR, MOYOHANEN S, NELKIN BD, BAYLIN SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996; 93: 9821-9826.
18. HOULE B, ROCHETTE-EGLY C, BRADLEY WEC. Tumor suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells. Proc Natl Acad Sci USA 1993; 90: 985-989.
19. JONES PA, LAIRD PW. Cancer epigenetics comes of age. Nat Genet 1999; 21: 163-167.
20. KLEIHUES P, BURGER PC, SCHEITHAUER BW. Histological typing of tumours of the central nervous system. World Health Organization international histological classification of tumours. 2nd ed. Berlin, Heidelberg: Springer Verlag, 1993.
21. LEID M, KASTNER P, CHAMBON P. Multiplicity generates diversity in the retinoic acid signalling pathways. TIBS 1992; 17: 427-433.
22. LIU Y, LEE MO, WANG HG, LI Y, HASHIMOTO Y, KLAUS M, et al. Retinoic acid receptor beta mediates the growth inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Mol Cell Biol 1996; 16: 1138-1149.
23. MILLER WHJ. The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer. Cancer 1998; 83: 1471-1482.
24. PHUPHANICH S, SCOTT C, FISCHBACH AJ, LANGER C, YUNG WKA. All-trans-retinoic acid: a phase II radiation therapy oncology group study (RTOG 91-13) in patients with recurrent malignant astrocytoma. J Neuro-Oncol 1997; 34: 193-200.
25. PICARD E, SEGUIN C, MONHOVEN N, ROCHETTE-EGLY C, SIAT J, BORRELLY J, et al. Expression of retinoid receptor genes and proteins in non-small-cell lung cancer. J Natl Cancer Inst 1999; 91: 1059-66.
26. PLÉNAT F, PICARD E, ANTUNES L, VIGNAUD JM, MARIE B, CHALABREYSSE P, et al. L'amplification des réactions immunologiques par dépôt catalytique aux sites de réaction de dérivés de la tyramine. Un gain décisif de sensibilité en immunohistochimie et en hybridation in situ. Ann Pathol 1997; 17: 17-23.
27. RUBERTE E, DOLLE P, CHAMBON P, MORRISS-KAY G. Retinoic acid receptors and cellular retinoid binding protein. II- Their differential pattern of transcription during early morphogenesis in mouse embryos. Development 1991; 111: 45-60.
28. RUTKA JT, DEARMOND SJ, GIBLIN JR, MCCULLOCH JR, WILSON CB, ROSENBLUM ML. Effects of retinoids on the proliferation, morphology and expression of glial fibrillary acidic protein of an anaplastic astrocytoma cell line. Int J Cancer 1988; 42: 419-427.
29. SCHMIDT EE, ICHIMURA K, MESSERLE KR, GOIKE HM, COLLINS VP. Infrequent methylation of CDKN2A (MTS1/p16) and rare mutation of both CDKN2A and CDKN2B (MTS2/p15) in primary astrocytic tumours. Br J Cancer 1997; 75: 2-8.
30. UMESONO K, MURAKAMI KK, THOMPSON CC, EVANS RM. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamine D3 receptors. Cell 1991; 65: 1255-1266.
31. VIRMANI AK, RATHI A, ZOCHBAUER-MULLER S, SACCHI N, FUKUYAMA Y, BRYANT D, et al. Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas. J Natl Cancer Inst 2000; 92: 1303-1307.