Testing the dose-response specification in epidemiology: Public health and policy consequences for lead

Environmental Health Perspectives

Volumn 113, Issue 9, 2005, Pages 1190-1195

  Rothenberg, Stephen J ^a   Rothenberg, Jesse C ^b  

^a INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Child IQ; Dose response; Health benefit; Health policy; Lead

Indexed keywords

LEAD;

ARTICLE; CALCULATION; ECONOMIC EVALUATION; ENVIRONMENTAL EXPOSURE; HEALTH CARE POLICY; HUMAN; INTELLIGENCE QUOTIENT; LEAD POISONING; MAJOR CLINICAL STUDY; MULTIPLE REGRESSION; OUTCOMES RESEARCH; PRIORITY JOURNAL; PUBLIC HEALTH; SCHOOL CHILD; STATISTICAL MODEL;

CHILD; CHILD, PRESCHOOL; COGNITION DISORDERS; CONFOUNDING FACTORS (EPIDEMIOLOGY); COST-BENEFIT ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; HUMANS; INFANT; INTELLIGENCE; LEAD; MODELS, STATISTICAL; PROSPECTIVE STUDIES; REGRESSION ANALYSIS;

EID: 25844524884     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.7691     Document Type: Article

References (27)

1. Baghurst PA, McMichael AJ, Wigg NR, Vimpani GV, Robertson EF, Roberts RJ, et al. 1992. Environmental exposure to lead and children's intelligence at the age of seven years. The Port Pirie Cohort Study. N Engl J Med 327(18):1279-1284.
2. Becher H. 1992. The concept of residual confounding in regression models and some applications. Stat Med 11:1747-1757.
3. Bellinger DC, Stiles KM, Needleman HL. 1992. Low-level lead exposure, intelligence and academic achievement: a long-term follow-up study. Pediatrics 90(6):855-861.
4. Benedetti A, Abrahamowicz M. 2004. Using generalized additive models to reduce residual confounding. Stat Med 23:3781-3801.
5. Caldwell BM, Bradley R. 1984. Home Observation for Measurement of the Environment, Little Rock, AK:University of Arkansas.
6. Canfield RL, Henderson CR Jr, Cory-Slechta DA, Cox C, Jusko TA, Lanphear BP. 2003. Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter. N Engl J Med 348(16):1517-1526.
7. CDC. 1991. Preventing Lead Poisoning in Young Children. Atlanta, GA:Centers for Disease Control and Prevention.
8. Davidson R, MacKinnon J. 1981. Several tests for model specification in the presence of alternative hypotheses. Econometrica 49:781-793.
9. Dietrich KN, Berger OG, Succop PA, Hammond PB, Bornschein RL. 1993. The developmental consequences of low to moderate prenatal and postnatal lead exposure: intellectual attainment in the Cincinnati Lead Study Cohort following school entry. Neurotoxicol Teratol 15(1):37-44.
10. Ernhart CB, Morrow-Tlucak M, Wolf AW, Super D, Drotar D. 1989. Low level lead exposure in the prenatal and early preschool periods: intelligence prior to school entry. Neurotoxicol Teratol 11(2):161-170.
11. Grosse SD, Matte TD, Schwartz J, Jackson RJ. 2002. Economic gains resulting from the reduction in children's exposure to lead in the United States. Environ Health Perspect 110:563-569.
12. Hastie TJ, Tibshirani R. 1990. Generalized Additive Models. New York:Chapman & Hall/CRC.
13. Lanphear BP, Hornung R, Khoury J, Yolton K, Baghurst P, Bellinger DC, et al. 2005. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environ Health Perspect 113:894-899; doi:10.1289/ehp.7688 [Online 18 March 2005].
14. Mielke HW, Anderson JC, Berry KJ, Mielke PW, Chaney RL, Leech M. 1983. Lead concentrations in inner-city soils as a factor in the child lead problem. Am J Public Health 73(12):1366-1369.
15. Mielke HW, Dugas D, Mielke PW Jr, Smith KS, Gonzales CR. 1997. Associations between soil lead and childhood blood lead in urban New Orleans and rural Lafourche Parish of Louisiana. Environ Health Perspect 105:950-954.
16. Mielke HW, Gonzales CR, Smith MK, Mielke PW. 1999. The urban environment and children's health: soils as an integrator of lead, zinc, and cadmium in New Orleans, Louisiana, U.S.A. Environ Res 81(2):117-129.
17. Nawrot TS, Thijs L, Den Hond EM, Roels HA, Staessen JA. 2002. An epidemiological re-appraisal of the association between blood pressure and blood lead: a mete-analysis. J Hum Hypertens 16(2):123-131.
18. Occupational Safety and Health Administration. 1979. Lead. 29CFR1910.1025.
19. Pacala SW, Bulte E, List JA, Levin SA. 2003. False alarm over environmental false alarms. Science 301:1187-1188.
20. Ramsey JB. 1969. Tests for specification errors in classical linear least squares regression analysis. J R Stat Soc Ser B 31:350-371.
21. Schnaas L, Rothenberg SJ, Perroni E, Martinez S, Hernandez C, Hernandez RM. 2000. Temporal pattern in the effect of postnatal blood lead level on intellectual development of young children. Neurotoxicol Teratol 22(6):805-810.
22. Schwartz J. 1994. Low-level lead exposure and children's IQ: a mete-analysis and search for a threshold. Environ Res 65(1):42-55.
23. Wasserman GA, Liu X, Lolacono NJ, Factor-Litvak P, Kline JK, Popovac D, et al. 1997. Lead exposure and intelligence in 7-year-old children: the Yugoslavia Prospective Study. Environ Health Perspect 105:956-962.
24. Wechsler D. 1967. Manual for Wechsler Preeschool and Primary Scale of Intelligence. San Antonio, TX:The Psychological Corporation.
25. Wechsler D. 1974. Manual for Wechsler Intelligence Scale for Children - Revised. San Antonio, TX:The Psychological Corporation.
26. Wechsler D. 1981. WISC-R-Español. Escala de intelligencia revisiada pare el nivel escolar. Mexico City:El Manual Moderno, SA.
27. Wechsler D. 1991. Manual for Wechsler Intelligence Scale for Children. 3rd ed. San Antonio, TX:The Psychological Corporation.