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Clinical Pharmacology and Therapeutics

Volumn 78, Issue 4, 2005, Pages 441-443

The CYP2C9 genotype does not influence sildenafil pharmacokinetics in healthy volunteers [3]

(6) Jetter, Alexander a Lazar, Andreas a Schömig, Edgar a Fuhr, Uwe a Kinzig Schippers, Martina b Sörgel, Fritz b

a UNIVERSITY OF COLOGNE (Germany)

b Institute for Biomedical and Pharmaceutical Research (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; DRUG METABOLITE; N NORSILDENAFIL; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; UNCLASSIFIED DRUG; WATER;

ALLELE; CONTROLLED STUDY; EXON; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENOTYPE; GRAPEFRUIT JUICE; HETEROZYGOTE; HUMAN; LETTER; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NORMAL HUMAN; PRIORITY JOURNAL; RANK SUM TEST;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ARYL HYDROCARBON HYDROXYLASES; BEVERAGES; CITRUS PARADISI; CROSS-OVER STUDIES; FOOD-DRUG INTERACTIONS; GENOTYPE; HUMANS; MALE; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PIPERAZINES; SULFONES;

EID: 25844472619 PISSN: 00099236 EISSN: None Source Type: Journal
DOI: 10.1016/j.clpt.2005.08.005 Document Type: Letter

Times cited : (7)

References (5)

1
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- In vitro biotransformation of sildenafil (Viagra): Identification of human cytochromes and potential drug interactions
- J.S. Warrington, R.I. Shader, L.L. von Moltke, D.J. Greenblatt In vitro biotransformation of sildenafil (Viagra) identification of human cytochromes and potential drug interactions Drug Metab Dispos 28 2000 392 397
- (2000) Drug Metab Dispos , vol.28 , pp. 392-397
- Warrington, J.S.¹ Shader, R.I.² Von Moltke, L.L.³ Greenblatt, D.J.⁴

2
- 0035039489
- Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil
- R. Hyland, E.G.H. Roe, B.C. Jones, D.A. Smith Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil Br J Clin Pharmacol 51 2001 239 248
- (2001) Br J Clin Pharmacol , vol.51 , pp. 239-248
- Hyland, R.¹ Roe, E.G.H.² Jones, B.C.³ Smith, D.A.⁴

3
- 0036159434
- Effects of grapefruit juice on the pharmacokinetics of sildenafil
- A. Jetter, M. Kinzig-Schippers, M. Walchner-Bonjean, U. Hering, J. Bulitta, P. Schreiner Effects of grapefruit juice on the pharmacokinetics of sildenafil Clin Pharmacol Ther 71 2002 21 29
- (2002) Clin Pharmacol Ther , vol.71 , pp. 21-29
- Jetter, A.¹ Kinzig-Schippers, M.² Walchner-Bonjean, M.³ Hering, U.⁴ Bulitta, J.⁵ Schreiner, P.⁶

4
- 2942620708
- Cytochrome P450 2C9 phenotyping using low-dose tolbutamide
- A. Jetter, M. Kinzig-Schippers, A. Skott, A. Lazar, D. Tomalik-Scharte, J. Kirchheiner Cytochrome P450 2C9 phenotyping using low-dose tolbutamide Eur J Clin Pharmacol 60 2004 165 171
- (2004) Eur J Clin Pharmacol , vol.60 , pp. 165-171
- Jetter, A.¹ Kinzig-Schippers, M.² Skott, A.³ Lazar, A.⁴ Tomalik-Scharte, D.⁵ Kirchheiner, J.⁶

5
- 11844304376
- Clinical consequences of cytochrome P450 2C9 polymorphisms
- J. Kirchheiner, J. Brockmöller Clinical consequences of cytochrome P450 2C9 polymorphisms Clin Pharmacol Ther 77 2005 1 16
- (2005) Clin Pharmacol Ther , vol.77 , pp. 1-16
- Kirchheiner, J.¹ Brockmöller, J.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.