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Volumn 13, Issue 21, 2005, Pages 6035-6044

Antitumor activity and distribution of pyrroloiminoquinones in the sponge genus Zyzzya

(11) Dijoux, Marie Geneviève a,d,e Schnabel, Peter C b,f Hallock, Yali F a,g Boswell, Jamie L a,h Johnson, Tanya R a Wilson, Jennifer A a Ireland, Chris M b Van Soest, Rob c Boyd, Michael R a,i Barrows, Louis R b Cardellina II, John H a,h

a NATIONAL CANCER INSTITUTE (United States)

b UNIVERSITY OF UTAH (United States)

c UNIVERSITY OF AMSTERDAM (Netherlands)

d Conseil Régional de Champagne Ardenne ^* (France)

e UFR de Pharmacie (France)

f Saba University (Netherlands)

g Grants and Contracts Operations Branch (United States)

h Screening Technologies Branch (United States)

i UNIVERSITY OF SOUTH ALABAMA (United States)

Author keywords

Antitumor; DNA damage; DNA intercalation; Pyrroloiminoquinone; Topoisomerase II; Zyzzya

Indexed keywords

3,7 DIMETHYLGUANINE; 6 DECHLOROBATZELLINE C; ANTINEOPLASTIC AGENT; ASCORBIC ACID; BATZELLINE C; BATZELLINE D; DAMIRONE A; DAMIRONE B; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; ISOBATZELLINE C; ISOBATZELLINE E; MAKALUVAMINE A; MAKALUVAMINE H; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CANCER CELL CULTURE; CANCER CENTER; CANCER SCREENING; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DNA CLEAVAGE; DNA DAMAGE; DRUG ACTIVATION; DRUG DISTRIBUTION; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENCY; FEMALE; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERCALATION COMPLEX; MALE; MOUSE; NONHUMAN; REDUCTION; SPONGE (PORIFERA); SUBSTITUTION REACTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DNA; HUMANS; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PORIFERA; PYRROLOIMINOQUINONES; SPECTROMETRY, FLUORESCENCE;

LATRUNCULIA; ZYZZYA;

EID: 25844453424 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2005.06.019 Document Type: Article

Times cited : (32)

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