Extremely high levels of alkaline phosphatase in hospitalized patients

Journal of Clinical Gastroenterology

Volumn 27, Issue 4, 1998, Pages 342-345

  Maldonado, Oscar ^a   Demasi, Ronald ^a   Maldonado, Yasmine ^a   Taylor, Mark ^a   Troncale, Frank ^a   Vender, Ronald ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOSPITAL OF SAINT RAPHAEL   (United States)

Author keywords

Abnormal liver tests; Alkaline phosphatase

Indexed keywords

ALKALINE PHOSPHATASE; BILIRUBIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADOLESCENT; ADULT; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BILE DUCT OBSTRUCTION; BILIRUBIN BLOOD LEVEL; CHILD; CHOLESTASIS; CLINICAL ARTICLE; COMMON BILE DUCT STONE; CYTOMEGALOVIRUS INFECTION; DISEASE ASSOCIATION; FEMALE; HEPATITIS; HOSPITAL PATIENT; HUMAN; LIVER HEMANGIOMA; LIVER METASTASIS; LIVER TOXICITY; MALE; MYCOBACTERIOSIS; PRIORITY JOURNAL; SARCOIDOSIS; SEPSIS;

ADULT; AGED; ALKALINE PHOSPHATASE; FEMALE; HOSPITALIZATION; HUMANS; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; MEDICAL RECORDS; MIDDLE AGED; RETROSPECTIVE STUDIES;

EID: 0031790558     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004836-199812000-00013     Document Type: Article

References (20)

1. Neuschwander-Tetri B. Common blood tests for liver diseases. Postgrad Med 1995;98:49-63.
2. Roberts WM. Variation of the phosphatase activity in the blood in disease. Br J Exp Pathol 1930;11:90-5.
3. Kaplan MM. Serum alkaline phosphatase: another piece is added to the puzzle. Hepatol 1986;6:256-58.
4. Wulkan RW, Leijnse B. Alkaline phosphatase and cholestasis. Ann Clin Biochem 1986;23:405-12.
5. Patton, RB. Spectacular elevations of serum alkaline phosphatase: clinical and pathological correlation. Henry Ford Hosp Med J 1970;18:211-4.
6. Payne TH, Cohn DL, et al. Marked elevation of serum alkaline phosphatase in patients with AIDS. J AIDS 1991;4:238-43.
7. Kaplan MM. Alkaline phosphatase. Gastroenterology 1972; 63:452-8.
8. Herrera JL. Abnormal liver enzyme levels: the spectrum of causes. Postgrad Med 1993;93:113-6.
9. Reischling JJ, Kaplan MM. Clinical use of serum enzymes in liver disease. Dig Dis Sci 1988;33:1601-14.
10. Sikuler E, Guetta V, Keynan A, Neumann L, Schaefter F. Abnormalities in bilirubin and liver enzyme levels in adult patients with bacteremia: a prospective study. Arch Intern Med 1989; 149:2246-8.
11. Brooks GS, Zimbler AG, Bodenheimer HC Jr, Burchard KW. Patterns of liver test abnormalities in patients with surgical sepsis. Am Surg 1991;57:656-62.
12. Fang MH, Ginsberg AL, Dobbins WO III. Marked elevation in serum alkaline phosphatase activity as manifestation of systemic infection. Gastroenterology 1980;78:592-7.
13. Chu CM, Lian YF, WU CS, et al. The hepatic manifestation in bacteremia [abstract]. Presented at the 10th annual meeting of the Gastroenterology Society of the Republic of China, March 1980.
14. Utili R, Abernathy CO, Zimmerman HJ. Inhibition of Na+, K+, ATP by endotoxin: a possible mechanism for endotoxin-induced cholestasis. J Infect Dis 1977;186:583-7.
15. Gimsom AES. Hepatic dysfunction during bacterial sepsis. Intensive Care Med 1987;13:162-6.
16. Dwirkin BM, Stahl RE, Giardina MA, et al. The liver in acquired immune deficiency syndrome: emphasis on patients with intravenous drug abuse. Am J Gastroenterol 1987;82:231-6.
17. Veitch MG, Lucas CR. Association of very high alkaline phosphatase levels with mycobacterium avium complex bacteremia in advance HIV disease [Abst Pub 7571]. Int Con AIDS 1992;8:144.
18. Mullick FG, Ishak KG. Hepatic injury associated with diphenylhydantoin therapy: a clinicopathologic study of 20 cases. Am J Clin Pathol 1980;74:442-52.
19. Spechler SJ, Spencer H Doos WG, Koff RS. Cholestasis and toxic epidermal necrolysis associated with phenytoin sodium ingestion: the role of the bile duct. Ann Intern Med 1981;95:455-6.
20. Mikhail TH, El-Snaf HA, Ibrahin KM, Anadallahr, El-Dessoukey EA. Evaluation of the effect of exposure on the liver on Egyptian tank welders. Z Ernahrunqswiss 1980;19:50-6.