Sensitivity of human cord blood cells to tetrachloroethylene: Cellular and molecular endpoints

Archives of Toxicology

Volumn 79, Issue 9, 2005, Pages 508-514

  Diodovich, Cristina ^a,b   Ferrario, Daniele ^a   Casati, Barbara ^a   Malerba, Ilaria ^a   Marafante, Erminio ^a   Parent Massin, Dominique ^b   Gribaldo, Laura ^a  

^a JOINT RESEARCH CENTRE   (Italy)

^b UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

Author keywords

Gene expression; Human cord blood cells; Macroarray; Tetrachloroethylene

Indexed keywords

ALPHA INTERFERON INDUCIBLE PROTEIN; ISOENZYME; ISOPROTEIN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 17; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C FOS; PROTEIN C JUN; TETRACHLOROETHYLENE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BLOOD CELL; BURST FORMING UNIT; CARCINOGENESIS; CELL ACTIVITY; CELL CYCLE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMING UNIT; CONTROLLED STUDY; ERYTHROCYTE; EXPOSURE; FLOW CYTOMETRY; GENE EXPRESSION; GRANULOCYTE; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; METASTASIS; MOLECULAR BIOLOGY; MOLECULAR CLONING; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STEM CELL; TIME; TUMOR; UMBILICAL CORD BLOOD;

APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ERYTHROID PROGENITOR CELLS; FETAL BLOOD; FLOW CYTOMETRY; GENES, TUMOR SUPPRESSOR; HUMANS; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SOLVENTS; TETRACHLOROETHYLENE; TETRAZOLIUM SALTS; THIAZOLES; TUMOR STEM CELL ASSAY; UP-REGULATION;

ANIMALIA;

EID: 25644446814     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-005-0662-8     Document Type: Article

References (17)

1. Diodovich C, Malerba I, Bowe G, Acquati F, Bianchi MG, Taramelli R, Parent-Massin D, Gribaldo L (2003) Naphthalene exposure: effects on gene expression and proliferation in human cord blood cells. J Biochem Mol Toxicol 17:286-294
2. EU (1999) Risk Assessment Report: Tetrachloroethylene. EU, Brussels
3. Ferroni C, Selis L, Mutti A, Folli D, Bergamaschi E, Franchini I (1992) Neurobehavioral and neuroendocrine effects of occupational exposure to perchloroethylene. Neurotoxicology 13(1):243-247
4. Ghantous H, Danielsson BR, Dencker L, Gorczak J, Vesterberg O (1986) Trichloroacetic acid accumulates in murine amniotic fluid after tri- and tetrachloroethylene inhalation. Acta Pharmacol Toxicol 58:105-114
5. Hoffmann R, Seidl T, Neeb M, Rolink A, Melchers F (2002) Changes in gene expression profiles in developing B cells of murine bone marrow. Genome Res 12:98-111
6. IARC (1999) Some halogenated hydrocarbons, vol 20. International Agency for Research on Cancer, Geneva
7. Lumpkin MH, Bruckner JV, Campbell JL, Dallas CE, White CA, Fisher JW (2003) Plasma binding of trichloroacetic acid in mice, rats, and humans under cancer bioassay and environmental exposure conditions. Drug Metab Dispos 31:1203-1207
8. Mundt KA, Birk T, Burch MT (2003) Critical review of the epidemiological literature on occupational exposure to perchloroethylene and cancer. Int Arch Occup Environ Health 76:473-491
9. Panaretakis T, Pokrovskaja K, Shoshan MC, Grander D (2003) Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax. Oncogene 22:4543-4556
10. Pessina A, Albella B, Bueren J, Brantom P, Casati S, Gribaldo L, Croera C, Gagliardi G, Foti P, Parchment R, Parent-Massin D, Sibiril Y, Van Den Heuvel R (2001) Prevalidation of a model for predicting acute neutropenia by colony forming unit granulocyte/macrophage (CFU-GM) assay. Toxicol In Vitro 15:729-740
11. Porras A, Zuluaga S, Black E, Valladares A, Alvarez AM, Ambrosino C, Benito M, Nebreda AR (2004) P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Mol Biol Cell 15:922-933
12. Puente XS, Pendas AM, Llano E, Velasco G, Lopez-Otin C (1996) Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res 56:944-949
13. Ramlow JM (1995) Apparent increased risk of leukemia in their highest category of exposure to tetrachloroethylene (PCE) in drinking water. Arch Environ Health 50:170-173
14. Reed L, Muench H (1938) A simple method of estimating fifty percent endpoints. Am J Hyg 27:493
15. Rosse T, Olivier R, Monney L, Rager M, Conus S, Fellay I et al (1998) BCL-2 prolongs cell survival after BAX-induced release of cytocrome c. Nature 391:496-499
16. Shao ZM, Nguyen M, Barsky SH (2000) Human breast carcinoma desmoplasia is PDGF initiated. Oncogene 19:4337-4345
17. Veals SA, Kessler DS, Josiah S, Leonard DG, Levy DE (1991) Signal transduction pathway activating interferon-alpha-stimulated gene expression. Br J Haematol 79:9-13