Selective down-regulation of extracellular matrix gene expression by bone marrow derived stem cell transplantation into infarcted myocardium

Circulation Journal

Volumn 69, Issue 10, 2005, Pages 1275-1283

  Xu, Xiaohua ^a   Xu, Zenglu ^a   Xu, Yuanyuan ^a   Cui, Guanghui ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Cardiac function; Cell transplantation; Hemodynamics; Myocardial infarction; Remodeling

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; INTERSTITIAL COLLAGENASE; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CORONARY ARTERY LIGATION; DOWN REGULATION; GENE EXPRESSION REGULATION; HEART HEMODYNAMICS; HEART INFARCTION; HEART LEFT VENTRICLE FILLING; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE RELAXATION; HEART VENTRICLE REMODELING; HEART WEIGHT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IN SITU HYBRIDIZATION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; UPREGULATION;

ANIMALS; BONE MARROW TRANSPLANTATION; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; RATS; RATS, WISTAR; VENTRICULAR REMODELING;

EID: 25644440687     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.69.1275     Document Type: Article

References (33)

1. Olivetti G, Capasso JM, Meggs LG, Sonnenblick EH, Anversa P. Cellular basis of chronic ventricular remodeling after myocardial infarction in rats. Circ Res 1991; 68: 856-869.
2. Weisman HF, Bush DE, Mannisi JA, Weisfeldt ML, Healy B. Cellular mechanisms of myocardial infarct expansion. Circulation 1988; 78: 186-201.
3. Lutgens E, Daemen MJ, de Muinck ED, Debets J, Leenders P, Smits JF. Chronic myocardial infarction in the mouse: Cardiac structural and functional changes. Cardiovasc Res 1999; 41: 586-593.
4. Van Kerckhoven R, Kalkman EA, Saxena PR, Schoemaker RG. Altered cardiac collagen and associated changes in diastolic function of infarcted rat hearts. Cardiovasc Res 2000; 46: 316-323.
5. Peterson JT, Li H, Dillon L, Bryant JW. Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat. Cardiovasc Res 2000; 46: 307-315.
6. Rohde LE, Ducharme A, Arroyo LH, Aikawa M, Sukhova GH, Lopez-Anaya A, et al. Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice. Circulation 1999; 99: 3063-3070.
7. Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction: Experimental observations and clinical implications. Circulation 1990; 81: 1161-1172.
8. Tomita S, Li RK, Weisel RD, Mickle DA, Kim EJ, Sakai T, et al. Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 1999; 100(Suppl): II-247-II-256.
9. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001; 410: 701-705.
10. Jain M, DerSimonian H, Brenner DA, Ngoy S, Teller P, Edge AS, et al. Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Circulation 2001; 103: 1920-1927.
11. Yoshiyama M, Hayashi T, Nakamura Y, Omura T, Izumi Y, Matsumoto R, et al. Effects of cellular cardiomyoplasty on ventricular remodeling assessed by Doppler echocardiography and topographic immunohistochemistry. Circ J 2004; 68: 580-586.
12. Tomita S, Mickle DA, Weisel RD, Jia ZQ, Tumiati LC, Allidina Y, et al. Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation. J Thorac Cardiovasc Surg 2002; 123: 1132-1140.
13. Pfeffer MA, Pfeffer JM, Fishbein MC, Fletcher PJ, Spadaro J, Kloner RA, et al. Myocardial infarct size and ventricular function in rats. Circ Res 1979; 44: 503-512.
14. Barbash IM, Chouraqui P, Baron J, Feinberg MS, Etzion S, Tessone A, et al. Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: Feasibility, cell migration, and body distribution. Circulation 2003; 108: 863-868.
15. Mulder P, Boujedaini H, Richard V, Henry JP, Renet S, Munter K, et al. Long-term survival and hemodynamics after endothelin-a receptor antagonism and angiotensin-converting enzyme inhibition in rats with chronic heart failure: Monotherapy versus combination therapy. Circulation 2002; 106: 1159-1164.
16. Whittaker P, Kloner RA, Boughner DR, Pickering JG. Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light. Basic Res Cardiol 1994; 89: 397-410.
17. Makino S, Fukuda K, Miyoshi S, Konishi F, Kodama H, Pan J, et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 1999; 103: 697-705.
18. Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002; 105: 93-98.
19. Shake JG, Gruber PJ, Baumgartner WA, Senechal G, Meyers J, Redmond JM, et al. Mesenchymal stem cell implantation in a swine myocardial infarct model: Engraftment and functional effects. Ann Thorac Surg 2002; 73: 1919-1925; discussion 1926.
20. Mangi AA, Noiseux N, Kong D, He H, Rezvani M, Ingwall JS, et al. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med 2003; 9: 1195-1201.
21. Fukuhara S, Tomita S, Yamashiro S, Morisaki T, Yutani C, Kitamura S, et al. Direct cell-cell interaction of cardiomyocytes is key for bone marrow stromal cells to go into cardiac lineage in vitro. J Thorac Cardiovasc Surg 2003; 125: 1470-1480.
22. McKay RG, Pfeffer MA, Pasternak RC, Markis JE, Come PC, Nakao S, et al. Left ventricular remodeling after myocardial infarction: A corollary to infarct expansion. Circulation 1986; 74: 693-702.
23. Yoshiyama M, Takeuchi K, Omura T, Kim S, Yamagishi H, Toda I, et al. Effects of candesartan and cilazapril on rats with myocardial infarction assessed by echocardiography. Hypertension 1999; 33: 961-968.
24. Ogawa K, Yaoita H, Okamoto M, Ikeda K, Shichishima T, Ohto H, et al. Transient improvement of left ventricular function after peripheral blood stem cell transplantation in a patient with myelodysplastic syndrome and dilated cardiomyopathy. Circ J 2004; 68: 958-960.
25. Sun Y, Zhang JQ, Zhang J, Lamparter S. Cardiac remodeling by fibrous tissue after infarction in rats. J Lab Clin Med 2000; 135: 316-323.
26. Moritani H, Kusachi S, Takeda K, Doi M, Ohnishi H, Komatsubara I, et al. Reperfusion accelerates the distribution of type I and III collagen messenger RNA expression after acute myocardial infarction: In situ hybridization in experimental infarction in rats. Coron Artery Dis 1999; 10: 89-96.
27. Thomas CV, Coker ML, Zellner JL, Handy JR, Crumbley AJ 3rd, Spinale FG. Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy. Circulation 1998; 97: 1708-1715.
28. Spinale FG, Coker ML, Heung LJ, Bond BR, Gunasinghe HR, Etoh T, et al. A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure. Circulation 2000; 102: 1944-1949.
29. Soejima H, Ogawa H, Sakamoto T, Miyamoto S, Kajiwara I, Kojima S, et al. Increased serum matrix metalloproteinase-1 concentration predicts advanced left ventricular remodeling in patients with acute myocardial infarction. Circ J 2003; 67: 301-304.
30. Spinale FG, Coker ML, Krombach SR, Mukherjee R, Hallak H, Houck WV, et al. Matrix metalloproteinase inhibition during the development of congestive heart failure: Effects on left ventricular dimensions and function. Circ Res 1999; 85: 364-376.
31. Lijnen PJ, Petrov VV, Fagard RH. Induction of cardiac fibrosis by transforming growth factor-beta (1). Mol Genet Metab 2000; 71: 418-435.
32. Deten A, Holzl A, Leicht M, Barth W, Zimmer HG. Changes in extracellular matrix and in transforming growth factor beta isoforms after coronary artery ligation in rats. J Mol Cell Cardiol 2001; 33: 1191-1207.
33. Boluyt MO, O'Neill L, Meredith AL, Bing OH, Brooks WW, Conrad CH, et al. Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure: Marked upregulation of genes encoding extracellular matrix components. Circ Res 1994; 75: 23-32.