G-protein activation by neurokinin-1 receptors is dynamically regulated during persistent nociception

Journal of Pharmacology and Experimental Therapeutics

Volumn 315, Issue 1, 2005, Pages 214-221

  Winter, Michelle K ^a   McCarson, Kenneth E ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FORMALDEHYDE; FREUND ADJUVANT; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MESSENGER RNA; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR AGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS COUPLING REACTION; DRUG RECEPTOR BINDING; HYPERALGESIA; IN SITU HYBRIDIZATION; LUMBAR SPINAL CORD; MALE; MEDICAL ASSESSMENT; NOCICEPTION; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR OCCUPANCY; RECEPTOR SENSITIVITY; SPINAL CORD DORSAL HORN; TISSUE SECTION; WITHDRAWAL REFLEX;

ANIMALS; FORMALDEHYDE; FREUND'S ADJUVANT; GTP-BINDING PROTEINS; HYPERALGESIA; INFLAMMATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-1; RNA, MESSENGER; SPINAL CORD;

EID: 25644439970     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.105.089565     Document Type: Article

References (37)

1. 1A receptor-mediated [35S]GTPγS binding in rat hippocampal membranes. Eur J Pharmacol 343:303-312.
2. Ansel JC, Kaynard AH, Armstrong CA, Olerud J, Bunnett N, and Payan D (1996) Skin-nervous system interactions. J Investig Dermatol 106:198-204.
3. Brennan TJ, Vandermeulen EP, and Gebhart GF (1996) Characterization of a rat model of incisional pain. Pain 64:493-501.
4. Collins S, Caron MG, and Lefkowitz RJ (1992) From ligand binding to gene expression: new insights into the regulation of G-protein-coupled receptors. Trends Biochem Sci 17:37-39.
5. De Felipe C, Herrero JF, O'Brien JA, Palmer JA, Doyle CA, Smith AJ, Laird JM, Belmonte C, Cervero F, and Hunt SP (1998) Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature (Lond) 392:394-397.
6. 125I]Bolton-Hunter substance P binding sites in human and rat skin. Neurosci Lett 99:287-292.
7. Dirig DM, Salami A, Rathbun ML, Ozaki GT, and Yaksh TL (1997) Characterization of variables defining hindpaw withdrawal latency evoked by radiant thermal stimuli. J Neurosci Methods 76:183-191.
8. Dubuisson D and Dennis SG (1977) The formalin test: a quantitative study of the analgesic effects of morphine, meperidine and brain stem stimulation in rats and cats. Pain 4:161-174.
9. Ferguson SS (2001) Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 53:1-24.
10. Fu KY, Light AR, and Maixner W (2000) Relationship between nociceptor activity, peripheral edema, spinal microglial activation and long-term hyperalgesia induced by formalin. Neuroscience 101:1127-1135.
11. Fu KY, Light AR, and Maixner W (2001) Long-lasting inflammation and long-term hyperalgesia after subcutaneous formalin injection into the rat hindpaw. J Pain 2:2-11.
12. Goff JR, Burkey AR, Goff DJ, and Jasmin L (1998) Reorganization of the spinal dorsal horn in models of chronic pain: correlation with behaviour. Neuroscience 82:559-574.
13. Grady EF, Garland AM, Gamp PD, Lovett M, Payan DG, and Bunnett NW (1995) Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor. Mol Biol Cell 6:509-524.
14. Henry JL, Yashpal K, Pitcher GM, Chabot J, and Coderre TJ (1999) Evidence for tonic activation of NK-1 receptors during the second phase of the formalin test in the Rat. J Neurosci 19:6588-6598.
15. Hershey AD, Dykema PE, and Krause JE (1991) Organization, structure, and expression of the gene encoding the rat substance P receptor. J Biol Chem 266:4366-4374.
16. Honore P, Menning PM, Rogers SD, Nichols ML, Basbaum AI, Besson JM, and Mantyh PW (1999) Spinal substance P receptor expression and internalization in acute, short-term and long-term inflammatory pain states. J Neurosci 19:7670-7678.
17. Hunskaar S, Fasmer OB, and Hole K (1985) Formalin test in mice, a useful technique for evaluating mild analgesics. J Neurosci Methods 14:69-76.
18. Jacques L, Couture R, Drapeau G, and Regoli D (1989) Capillary permeability induced by intravenous neurokinins: receptor characterization and mechanism of action. Naunyn-Schmiedeberg's Arch Pharmacol 340:170-179.
19. Kar S, Rees RG, and Quirion R (1994) Altered calcitonin gene-related peptide, substance P and enkephalin immunoreactivities and receptor binding sites in the dorsal spinal cord of the polyarthritic rat. Eur J Neurosci 6:345-354.
20. Krause JE, Cremins JD, Carter MS, Brown ER, and MacDonald MR (1989) Solution hybridization-nuclease protection assays for sensitive detection of differentially spliced substance P- and neurokinin A-encoding messenger ribonucleic acids. Methods Enzymol 168:634-652.
21. Krause JE, Takeda Y, and Hershey AD (1992) Structure, functions and mechanisms of substance P receptor action. J Investig Dermatol 98:2S-7S.
22. q/11, is a substrate of β-adrenergic receptor kinase 1 and 2. J Biol Chem 268:9161-9164.
23. 35S] GTPγS binding to cell membranes. Methods Mol Biol 83:107-116.
24. 2)11]substance P, a new selective radioligand for the NK1 receptor. Eur J Pharmacol 184:97-108.
25. Ma QP and Woolf CJ (1996) Progressive tactile hypersensitivity: an inflammationinduced incremental increase in the excitability of the spinal cord. Pain 67:97-106.
26. Mantyh PW, Allen CJ, Ghilardi JR, Rogers SD, Mantyh CR, Liu H, Basbaum AI, Vigna SR, and Maggio JE (1995) Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo. Proc Natl Acad Sci USA 92:2622-2626.
27. McCarson KE (1999) Central and peripheral expression of neurokinin-1 and neurokinin-3 receptor and substance P-encoding messenger RNAs: peripheral regulation during formalin-induced inflammation and lack of neurokinin receptor expression in primary afferent sensory neurons. Neuroscience 93:361-370.
28. McCarson KE and Krause JE (1994) NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increased during adjuvant or formalin-induced nociception. J Neurosci 14:712-720.
29. McCarson KE and Krause JE (1995) The formalin-induced expression of tachykinin peptide and neurokinin receptor messenger RNAs in rat sensory ganglia and spinal cord is modulated by opiate preadministration. Neuroscience 64:729-739.
30. McCarson KE and Krause JE (1996) The neurokinin-1 receptor antagonist LY306,740 blocks nociception-induced increases in dorsal horn neurokinin-1 receptor gene expression. Mol Pharmacol 50:1189-1199.
31. Radhakrishnan V and Henry JL (1991) Novel substance P antagonist, CP-96,345, blocks responses of cat spinal dorsal horn neurons to noxious cutaneous stimulation and to substance P. Neurosci Lett 132:39-43.
32. Sakurada T, Katsumata K, Yogo H, Tan-No K, Sakurada S, and Kisara K (1993) Antinociception induced by CP 96,345, a non-peptide NK-1 receptor antagonist, in the mouse formalin and capsaicin tests. Neurosci Lett 151:142-145.
33. Seabrook GR, Shepheard SL, Williamson DJ, Tyrer P, Rigby M, Cascieri MA, Harrison T, Hargreaves RJ, and Hill RG (1996) L-733,060, a novel tachykinin NK1 receptor antagonist; effects in [Ca2]i mobilisation, cardiovascular and dural extravasation assays. Eur J Pharmacol 317:129-135.
34. Sovago J, Dupuis DS, Gulyas B, and Hall H (2001) An overview on functional receptor autoradiography using [35S]GTPS. Brain Res Brain Res Rev 38:149-164.
35. Stucky CL, Galeazza MT, and Seybold VS (1993) Time-dependent changes in Bolton-Hunter-labeled 125I-substance P binding in rat spinal cord following unilateral adjuvant-induced peripheral inflammation. Neuroscience 57:397-409.
36. Tsuchida K, Shigemoto R, Yokota Y, and Nakanishi S (1990) Tissue distribution and quantitation of the mRNAs for three rat tachykinin receptors. Eur J Biochem 193:751-757.
37. Wang X and Marvizon JC (2002) Time-course of the internalization and recycling of neurokinin 1 receptors in rat dorsal horn neurons. Brain Res 944:239-247.