Altered dendritic arborization of amygdala neurons in young adult rats orally intubated with Clitorea ternatea aqueous root extract

Phytotherapy Research

Volumn 19, Issue 7, 2005, Pages 592-598

  Rai, Kiranmai S ^a   Murthy, K Dilip ^b   Rao, Muddanna S ^a   Karanth, K Sudhakar ^c  

^a KASTURBA MEDICAL COLLEGE   (India)

^b MELAKA MANIPAL MEDICAL COLLEGE   (India)

^c NITTE DEEMED TO BE UNIVERSITY   (India)

Author keywords

Amygdala neurons; Clitoria ternatea; Dendritic arborization; Learning and memory; Passive avoidance

Indexed keywords

CLITOREA TERNATEA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAMERA; CONTROLLED STUDY; DECAPITATION; DENDRITIC CELL; FEMALE; GOLGI STAIN; LEARNING; LONG TERM MEMORY; MALE; NERVE CELL; NONHUMAN; PASSIVE AVOIDANCE; PLANT ROOT; RAT;

ADMINISTRATION, ORAL; AMYGDALA; ANIMALS; AVOIDANCE LEARNING; CLITORIA; DENDRITES; MEMORY; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, WISTAR;

CLITORIA TERNATEA; RATTUS NORVEGICUS;

EID: 25444523756     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1657     Document Type: Article

References (60)

1. Abe K. 2001. Modulation of hippocampal long-term potentiation by the amygdala: a synaptic mechanism linking emotion and memory. Jpn J Pharmacol 86: 18-22.
2. Adolphs R, Cahill L, Schul R, Babinsky R. 1997. Impaired declarative memory for emotional material following bilateral amygdala damage in humans. Learn Mem 4: 291-300.
3. Alvarez EO, Ruarte MB. 2004. Glutamic acid and histamine-sensitive neurons in the ventral hippocampus and the basolateral amygdala of the rat: functional interaction on memory and learning process. Behav Brain Res 152: 209-219.
4. Antoniadis EA, McDonald RJ. 2000. Amygdala, hippocampus and discriminative fear conditioning to context. Behav Brain Res 108: 1-19.
5. Barnes CA, McNaughton BL. 1980. Spatial memory and hippocampal synaptic plasticity in middle-aged and senescent rats. In: Stein D (ed.), Psychobiology of Aging: Problems and Perspectives. Elsevier, Amsterdam 253-272.
6. Bartus RT, Dean RL, Goas JA, Lippa AS. 1980. Age-related changes in passive avoidance retention: Modulation with dietary choline. Science 209: 301-303.
7. Bharathi H, Rao MS, Murthy KD. 1999. Pyramid environment enhances learning and memory-a behavioural and morphological study. In (Abstract) International Congress on Frontiers in Pharmacology and Therapeutics in 21st Century. Indian Pharmacological Society, New Delhi, India.
8. Bharathi H, Rao MS, Murthy KD. 2000. Anti-stress effects of environment within a pyramid model - A behavioral and morphological study in mice. In (Abstract) Third Congress. Federation of Indian Physiological Societies (FIPS) Calcutta, India.
9. Cahill L, Hair RJ, Fallon J, et al. 1996. Amygdala activity at encoding correlated with long-term, free recall of emotional information. Proc Natl Acad Sci USA 93: 8016-8021.
10. Cahill L, McGaugh JL. 1998. Mechanisms of emotional arousal and lasting declarative memory. Trends Neurosci 21: 294-299.
11. Escobar C, Salas M. 1993. Neonatal undernutrition and amygdaloid nuclear complex development: an experimental study in the rat. Exp Neurol 122: 311-318.
12. Fiore M, Angelucci F, Aloe L, Ianitelli A, Korf J. 2003. Nerve growth factor and brain derived neurotrophic factor in schizophrenia and depression: Finding in humans and animal models. Curr Neuropharmacol 1: 109-123.
13. Gundappa G, Desiraju T. 1988. Deviations in brain development of F2 generation on caloric under nutrition and scope of their prevention of rehabilitation: alterations in dendritic spine production and pruning of pyramidal neurons of lower laminae of motor cortex and visual cortex. Brain Res 456: 205-223.
14. Hamann SB, Cahill L, McGaugh JL, Squire LR. 1997. Intact enhancement of declarative memory of emotional material in amnesia. Learn Mem 4: 301-309.
15. Harley CW. 1987. A role for norepinephrine in arousal, emotion and learning?: limbic modulation by norepinephrine and the Kety hypothesis. Prog Neuropsychopharmaol Biol Psychiatry 11: 419-458.
16. Himi T, Saito H, Nakajima T. 1990. Spider toxin (JSTX-3) inhibits the memory retrieval of passive avoidance tests. J Neural Transm Gen Sect 80: 79-89.
17. Huang YY, Kandel ER. 1996. Modulation of both the early and late phase of mossy fiber LTP by the activation of β-adrenergic receptors. Neuron 16: 611-617.
18. Indurwade NH, Biyani KR. 2000. Evaluation of comparative and combined depressive effect of Brahmi, Shankapushpi and Jatamansi in mice. Indian J Med Sci 54: 339-341.
19. Introini-Collision IB, Castellano C, McGaugh JL. 1994. Interaction of gabaergic and β-noradrenergic drugs in the regulation of memory storage. Behav Neural Biol 61: 150-155.
20. Introini-Collision IB, Dalmaz C, McGaugh JL. 1996. Amygdala β-noradrenergic influences on memory storage involve cholinergic activation. Neurobiol Learn Mem 65: 57-64.
21. Introini-Collision IB, Nagahara AH, McGaugh JL. 1989. Memory enhancement with intra-amygdala post-training naxalone is blocked by concurrent administration of propranolol. Brain Res 476: 94-101.
22. Jean P, Pascal R, Susan JS. 1999. Attenuation of emotional and nonemotional memories after their reactivation: Role of β adrenergic receptors. J Neurosci 19: 6623-6628.
23. Kesner RP. 1992. Learning and memory in rats with an emphasis on the role of the amygdala. In The Amygdala: Neurobiological Aspects of Emotion, Memory and Mental Dysfunction. Wiley-Liss: New York, USA; 379-399.
24. Kumar KB, Karanth KS. 1991. Enhanced retrieval of unpleasant memory in helpless rats. Biol Psychiatry 30: 493-501.
25. Mahajan DS, Desiraju T. 1988. Alterations of dendritic branching and spine densities of hippocampal CA3 pyramidal neurons induced by operant conditioning in the phase of brain growth spurt. Exp Neurol 100: 1-15.
26. McGaugh JL. 1989. Involvement of hormonal and neuromodulatory systems in the regulation of memory storage. Annu Rev Neurosci 12: 255-287.
27. McGaugh JL, Cahill L. 1997. Interaction of neuromodulatory systems in modulating memory storage. Behav Brain Res 83: 31-38.
28. McGaugh JL, Cahill L, Roozendaal B. 1996. Involvement of amygdala in memory storage interaction with other brain systems. Proc Natl Acad Sci USA 93: 13508-13514.
29. McNaughton BL, Barnes CA, Andersen P. 1981. Synaptic efficiency and EPSP summation in granule cells of rat fascia dentate studied in vitro. J Neurophysiol 46: 952-966.
30. Murthy KD, Desiraju T. 1991. Synapses in developing cingulate and hippocampal cortices in undernourished rats. Neuro Report 2: 433-436.
31. Nader K, Schafe GE, Le-Doux JE. 2000. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406: 722-726.
32. Pikkarainen M, Ronkko S, Savander V, Insausti R, Pitakenen A. 1999. Projections from the lateral, basal, and accessory basal nuclei of the amygdala to the hippocampal formation in rat. J Comp Neurol 403: 229-260.
33. Poremba A, Gabriel M. 1999. Amygdala neurons mediate acquisition but not maintenance of instrumental avoidance behavior in rabbits. J Neurosci 19: 9635-41.
34. Rai KS, Murthy KD, Karanth KS, Rao MS. 2001. Clitoria ternatea (Linn) root extract treatment during growth spurt period enhances learning and memory in rats. Indian J Physiol Pharmacol 45: 305-313.
35. Rai KS, Murthy KD, Rao MS, Karanth KS. 2000. Clitoria ternatea (Linn) root extract treatment in rats during growth spurt period affects dendritic morphology of hippocampal CA3 neurons. In Third Congress. Federation of Indian Physiological Societies (FIPS), Calcutta (Abstract no. 4.5): Calcutta, India; 45.
36. Rai KS, Murthy KD, Karanth KS, Nalini K, Rao MS, Srinivasan KK. 2002. Clitoria ternatea root extract enhances acetylcholine content in rat hippocampus. Fitoterapia 73: 685-689.
37. Rao MKG. 2002. Effect of Centella asiatica extract on rat central nervous system-a behavioral and morphological study. PhD Thesis. Submitted to MAHE-Deemed University, Manipal, India.
38. Rao BSS, Desiraju T, Raju TR. 1993. Neuronal plasticity induced by self-stimulation rewarding experiences in rats-a study on alteration in dendritic branching in pyramidal neurons of hippocampus and motor cortex. Brain Res 627: 216-224.
39. Rao BSS, Madhavi R, Sunanda, Raju TR. 2001. Complete reversal of dendritic atrophy in CA3 neurons of the hippocampus by rehabilitation in restraint stressed rats. Curr Sci 80: 653-659.
40. Richter Levin G, Akirav I. 2001. Amygdala-hippocampus dynamic interaction in relation to memory. Mol Neuro biol 22: 11-20.
41. Rolls ET. 2000. Memory systems in the brain. Annu Rev Psychol 51: 599-630.
42. Ronald SD. 2002. Regulation of neurogenesis by stress and antidepressant treatment. J Am Acad Child Adolesc Psychiatry 41: 745-748.
43. Sarvey JM. 1988. Protein synthesis in long-term potentiation and norepinephrine-induced long-lasting potentiation in hippocampus. In Long-term Potentiation: from Biophysics to Behavior. AR Liss: New York, USA; 329-353.
44. Shukia B, Khanna NK, Godhwani JL. 1987. Effect of Brahmi rasayan on central nervous system. J Ethnopharmacol 21: 65-74.
45. Singh HK, Dhawan BN. 1982. Effect of Bacopa monnieri (Linn) extract on avoidance responses in rat. J Ethnopharmacol 5: 205-214.
46. Squire LR, Schlapfer WT. 1981. Handbook of Biological Psychiatry, Vanpraag HM, Lader MH, Rafaelsen OJ, Sachar EJ (eds). Raven Press: New York, USA; 249.
47. Stancampiano R, Cocco S, Cugusi C, Sarais L, Fadda F. 1999. Serotonin and acetylcholine release response in the rat hippocampus during a spatial memory task. Neuroscience 89: 1135-1143.
48. Stough C, Lloyd J, Clarke J, et al. 2001. The chronic effects of an extract of Bacopa monnieri on cognitive function in healthy human subjects. Psychopharmacology 156: 481-484.
49. Sudha S, Lakshmana MK, Pradhan N. 1995. Changes in learning and memory, acetylcholinesterase activity and monoamines in brain after chronic carbamazepine administration in rats. Epilepsia 36: 416-422.
50. Sunanda Rao MS, Raju TR. 1995. Effects of chronic restraint stress on dendritic spines and excrescences of hipppocampal CA3 pyramidal neurons-a quantitative study. Brain Res 694: 312-317.
51. Tabert MH, Borod JC, Tang CY, et al. 2001. Differential amygdala activation during emotional decision and recognition memory tasks using unpleasant words: an MRI study. Neuropsychologia 39: 556-573.
52. Takashina K, Saito H, Nishiyama N. 1995. Preferential impairment of avoidance performances in amygdala-lesioned mice. Jpn J Pharmacol 67: 107-115.
53. Tyler WJ, Alonso M, Bramham CR, Pozzo-Miller LD. 2002. From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learning Mem 9: 224-237.
54. van-der-Zee EA, Luiten PG. 1999. Muscarinic acetylcholine receptors in the hippocampus, neocortex and amygdala: a review of immunocytochemical localizationin relation to learning and memory. Prog Neurobiol 58: 409-471.
55. Vincent R. 2002. Anti-stress effect of Ocimum sanctum on rat CNS - An experimental study. PhD Thesis. Submitted to MAHE-Deemed University, Manipal, India.
56. Vyas A, Mitra R, Rao BSS, Chattarji S. 2002. Chronic stress induces contrasting patterns of dendritic remodelling in hippocampal and amygdaloid neurons. J Neurosci 22: 6810-6818.
57. Wong ST, Athos J, Figueroa XA, et al. 1999. Calcium stimulated adenylyl cyclase activity is critical for hippocampus dependent long-term memory and late phase LTP. Neuron 23: 787-798.
58. Xu XH, Zhang ZG, Wu FM. 2000. Improving effect of NGF by intrahippocampal injection on aging-related memory impairment. Yao Xue Xue Bao 35: 729-732.
59. Yaniv D, Desmedt A, Jaffard R, Richter Levin G. 2004. The amygdala and appraisal processes: stimulus and response complexity as an organizing factor. Brain Res Rev 44: 179-186.
60. Yaniv D, Vouimbaa, Diamond DM, Richter Levin G. 2003. Simultaneous induction of long-term potentiation in the hippocampus and the amygdala by entorhinal cortex activation: mechanistic and temporal profiles. Neuroscience 120: 1125-1135.