Establishment of a germ-somatic cell coculture model for toxicity assessment of environmental endocrine disrupters

Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering

Volumn 40, Issue 10, 2005, Pages 1917-1928

  Mi, Yuling ^a   Zhang, Caiqiao ^a   Zeng, Weidong ^a   Tang, Xinyan ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

2,4 dichlorophenoxyacetic acid; Busulfan; Environmental endocrine disrupters; Polychlorinated biphenyls; Screening model; Testicular cells

Indexed keywords

CELLS; CYTOLOGY; MATHEMATICAL MODELS; POLYCHLORINATED BIPHENYLS; TOXICITY;

2,4-DICHLOROPHENOXY ACIDS; BUSULFAN; ENVIRONMENTAL ENDOCRINE DISRUPTERS; SCREENING MODELS; TESTICULAR CELLS;

BACTERIA;

2,4 DICHLOROPHENOXYACETIC ACID; AROCLOR 1254; BUSULFAN; ENDOCRINE DISRUPTOR; INSULIN; POLYCHLORINATED BIPHENYL DERIVATIVE; SELENITE; TRANSFERRIN;

ANIMAL CELL; APOPTOSIS; CELL COUNT; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CHICKEN; COCULTURE; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; ENVIRONMENT; GERM CELL; MODEL; NONHUMAN; SOMATIC CELL; TESTIS CELL; TOXICITY;

ANIMALS; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CHICK EMBRYO; CULTURE MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; GERM CELLS; MALE; TESTIS; TOXICITY TESTS;

EID: 25444477785     PISSN: 10934529     EISSN: None     Source Type: Journal    
DOI: 10.1080/10934520500184392     Document Type: Conference Paper

References (33)

1. Pan, X.; Inouye, K.; Ito, T.; Nagai, H.; Takeuchi, Y.; Miyabara, Y.; Tohyama, C.; Nohara, K. Evaluation of relative potencies of PCB126 and PCB169 for the immunotoxicities in ovalbumin (OVA)-immunized mice. Toxicology 2004, 204, 51-60.
2. Tilson, H.A.; Kodavanti, P.R.S. The neurotoxicity of polychlorinated biphenyls. Neurotoxicology 1998, 19, 517-526.
3. Hany, J.; Lilienthal, H.; Sarasin, A.; Roth-Härer, A.; Fastabend, A.; Dunemann, L.; Lichtensteiger, W.; Winneke, G. Developmental exposure of rats to a reconstituted PCB mixture or Aroclor 1254: effects on organ weights, aromatase activity, sex hormone levels, and sweet preference behavior. Toxicol. Appl. Pharmacol. 1999, 158, 231-243.
4. Faqi, A.S.; Dalsenter, P.R.; Mathar, W.; Heinrich-Hirsch, B.; Chahoud, I. Reproductive toxicity and tissue concentrations of 3,3′,4,4′- tetrachlorobiphenyl (PCB 77) in male adult rats. Hum. Exp. Toxicol. 1998, 17, 151-156.
5. Khan, I.A.; Thomas, P. Disruption of neuroendocrine function in Atlantic Croaker exposed to Aroclor 1254. Mar. Environ. Res. 1996, 42, 145-149.
6. Kuchenhoff, A.; Eckard, R.; Buff, K.; Fischer, B. Stage-specific effects of defined mixtures of polychlorinated biphenlys on in vitro development of rabbit preimplantation embryos. Mol. Reprod. Dev. 1999, 54, 126-134.
7. Pflieger-Bruss, S.; Hanf, V.; Behnisch, P.; Hagenmaier, H.; Rune, G.M. Effects of single polychlorinated biphenyls on the morphology of cultured rat tubuli seminiferi. Andrologia 1999, 31, 77-82.
8. Njiwa, J.R.K.; Müller, P.; Klein, R. Binary mixture of DDT and Arochlor1254: effects on sperm release by Danio rerio. Ecotoxicol. Environ. Safety 2004, 58, 211-219.
9. Zhang, C.; Fang, C.; Liu, L.; Xia, G.; Qiao H. Disrupting effects of polychlorinated biphenyls on gonadal development and reproductive functions in chickens. J. Environ. Sci. Health 2002, A37, 509-519.
10. Zhang, C.; Qiao, H. Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks. J. Zhejiang. Univ. (Science) 2004, 5, 193-197.
11. Gierthy, J.F.; Arcaro, K.F.; Floyd, M. Assessment of PCB estrogenicity in a human breast cancer cell line. Chemosphere 1997, 34, 1495-1505.
12. Pedernera, E.; Solis, L.; Peralta, I.; Velázquez, P.N. Proliferative and steroidogenic effects of follicle-stimulating hormone during chick embryo gonadal development. Gen. Comp. Endocrinol. 1999, 116, 213-220.
13. Pineau, C.; Dupaix, A.; Jégou, B. The co-culture of Sertoli cells and germ cells: applications in toxicology. Toxicol. In Vitro 1999, 13, 513-520.
14. Sinha, N.; Adhikari, N.; Narayan, R.; Saxena, D.K. Cytotoxic effect of endosulfan on rat Sertoli-germ cell coculture. Reprod. Toxicol. 1999, 13, 291-294.
15. Takahashi, K.L.; Aoyama, H.; Kawashima, K.; Teramoto, S. Effects of dinoseb, 4,6-dinitro-o-cresol, and 2,4-dinitrophenol on rat Sertoli-germ cell co-cultures. Reprod. Toxicol. 2003, 17, 247-252.
16. Crain, D.A.; Spiteri, I.D.; Guillette L.J. Jr. The functional and structural observations of the neonatal reproductive system of alligators exposed in ovo to atrazine, 2,4-D, or estradiol. Toxicol. Ind. Health 1999, 15, 180-185.
17. Bucci, L.R.; Meistrich, M.L. Effects of busulfan on murine spermatogenesis: cytotoxicity, sterility, sperm abnormalities, and dominant lethal mutations. Mutat. Res. 1987, 176, 259-268.
18. van Keulen, C.J.G.; de Rooij, D.G. The recovery from various gradations of cell loss in the mouse seminiferous epithelium and its implications for the spermatogonial stem cell renewal theory. Cell Tissue Kinet. 1974, 7, 549-558.
19. Xie, M.; Zhang, C. Estrogenic and toxic effects of polychlorinated biphenyls on cultured ovarian germ cells of embryonic chickens. Reprod. Toxicol. 2004, 19, 79-86.
20. Mi, Y.; Zhang, C.; Xie, M.; Zeng, W. Effects of follicle-stimulating hormone and androgen on proliferation of cultured testicular germ cells of embryonic chickens. Gen. Comp. Endocrinol. 2004, 138, 237-246.
21. Iguchi, T. Cellular effects of early exposure to sex hormones and antihormones. Int. Rev. Cytol. 1992, 139, 1-57.
22. Horii, T.; Nagao, Y.; Tokunaga, T.; Imai, H. Serum-free culture of murine primordial germ cells and embryonic germ cells. Theriogenology 2003, 59, 1257-1264.
23. Crews, C.M.; Erikson, R.L. Extracellular signals reversible protein phosphorylation: what to mek of it all. Cell 1993, 74, 215-217.
24. Oka, H.; Chatani, Y.; Hoshino, R.; Ogawa, O.; Kakehi, Y.; Terachi, T.; Okada, Y.; Kawaichi, M.; Kohno, M.; Yashida, O. Constitutive activation of mitogen-activated protein (MAP) kinases in humen renal cell carcinoma. Cancer Res. 1995, 55, 4182-4187.
25. Chaudhary, J.; Skinner, M.K. Comparative sequence analysis of the mouse and human transferrin promoters: hormonal regulation of the transferrin promoter in Sertoli cells. Mol. Reprod. Dev. 1998, 50, 273-283.
26. Cooke, P.S.; Zhao, Y.D.; Hansen, L.G. Neonatal polychlorinated biphenyl treatment increases adult testis size and sperm production in the rat. Toxicol. Appl. Pharmacol. 1996, 136, 112-117.
27. Shiraishi, F.; Okumura, T.; Nomachi, M.; Serizawa, S.; Nishikawa, J.; Edmonds, J.S.; Shiraishi, H.; Morita, M. Estrogenic and thyroid hormone activity of a series of hydroxy-polychlorinated biphenyls. Chemosphere 2003, 52, 33-42.
28. Andersson, P.L.; Blom, A.; Johannisson, A.; Pesonen, M.; Tysklind, M.; Berg, A.H.; Olsson, P.E.; Norrgren, L. Assessment of PCBs and hydroxylated PCBs as potential xenoestrogens: In vitro studies based on MCF-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. Arch. Environ. Contam. Toxicol. 1999, 37, 145-150.
29. Mi, Y.; Zhang, C. Toxic and hormonal effects of polychlorinated biphenyls on cultured testicular germ cells of embryonic chickens. Toxicol. Lett. 2005, 155, 297-305.
30. Schrader, T. J.; Cooke, G. M. Effects of Aroclors and individual PCB congeners on activation of the human androgen receptor in vitro. Reprod. Toxicol. 2003, 17, 15-23.
31. Oruc, E.O.; Sevgiler, Y.; Uner, N. Tissue-specific oxidative stress responses in fish exposed to 2,4-D and azinphosmethyl. Comp. Biochem. Physiol. Part C 2004, 137, 43-51.
32. Stebbins-Boaz, B.; Fortner, K.; Frazier, J.; Piluso, S.; Pullen, S.; Rasar, M.; Reid, W.; Sinclair, K.; Winger, E. Oocyte maturation in Xenopus laevis is blocked by the hormonal herbicide, 2,4-dichlorophenoxy acetic acid. Mol. Reprod. Dev. 2004, 67, 233-242.
33. Johnson, J.; Canning, J.; Kaneko, T.; Pru, J.K.; Tilly, J.L. Germline stem cells and follicular renewal in the postnatal mammalian ovary. Nature 2004, 428, 145-150.