The use of non-bronchoscopic brushings to study the paediatric airway

Respiratory Research

Volumn 6, Issue , 2005, Pages

  Lane, Catherine ^a   Burgess, Scott ^a,b   Kicic, Anthony ^a   Knight, Darryl A ^c   Stick, Stephen ^a,b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b PRINCESS MARGARET HOSPITAL FOR CHILDREN   (Australia)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DNA; RNA;

ARTICLE; ASTHMA; AUSTRALIA; BRONCHOSCOPY; CELL COUNT; CHILDHOOD DISEASE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; COUGHING; CYTOPATHOLOGY; DNA MICROARRAY; EPITHELIUM CELL; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; MALE; NURSING STAFF; PEDIATRIC HOSPITAL; PEDIATRIC SURGERY; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT DISEASE; RISK ASSESSMENT; RNA EXTRACTION; SAMPLING; SCHOOL CHILD; WESTERN BLOTTING; BRONCHUS; CELL SURVIVAL; CHILD; CLINICAL TRIAL; COUGH; CULTURE TECHNIQUE; CYTODIAGNOSIS; FEMALE; LABORATORY DIAGNOSIS; PATHOLOGY; PROCEDURES; RESPIRATORY TRACT MUCOSA;

ASTHMA; BRONCHI; BRONCHOSCOPY; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CHILD; COHORT STUDIES; COUGH; CYTODIAGNOSIS; EPITHELIAL CELLS; FEMALE; HUMANS; MALE; RESPIRATORY MUCOSA; SPECIMEN HANDLING;

EID: 25444449509     PISSN: 1465993X     EISSN: None     Source Type: Journal    
DOI: 10.1186/1465-9921-6-53     Document Type: Article

References (8)

1. Romagnoli M, Vachier I, Vignola AM, Godard P, Bousquet J, Chanez P: Safety and cellular assessment of bronchial brushing in airway diseases. Respir Med 1999, 93(7):461-466.
2. Doherty G, Christie S, Skibinski G, Puddicombe S, Warke T, De Courcey F, Cross A, Lyons J, Ennis M, Shields M et al: Non-bronchoscopic sampling and culture of bronchial epithelial cells in children. Clin Exp Allergy 2003, 33(9):1221-1225.
3. Lane C, Knight D, Burgess S, Franklin P, Horak F, Legg J, Moeller A, Stick S: Epithelial inducible nitric oxide synthase activity is the major determinant of nitric oxide concentration in exhaled breath. Thorax 2004, 59(9):757-760.
4. Knight DA, Lane CL, Stick SM: Does aberrant activation of the epithelial-mesenchymal trophic unit play a key role in asthma or is it an unimportant sideshow? Curr Opin Pharmacol 2004, 4(3):251-256.
5. Asher M, Keil U, Anderson H, Beasley R, Crane J, Martinez F, Mitchell E, Pearce N, Sibbald B, Stewart A et al: International Study of Asthma and 15 Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J 1995, 8(3):483-491.
6. Baugh LR, Hill AA, Brown EL, Hunter CP: Quantitative analysis of mRNA amplification by in vitro transcription. Nucleic Acids Res 2001, 29(5):E29.
7. Campbell AM, Chanez P, Vignola AM, Bousquet J, Couret I, Michel FB, Godard P, Paul-Lacoste P, Vachier I, Roux S et al: Functional characteristics of bronchial epithelium obtained by brushing from asthmatic and normal subjects. Am Rev Respir Dis 1993, 147(3):529-534.
8. Vignola AM, Campbell AM, Chanez P, Bousquet J, Paul-Lacoste P, Michel FB, Godard P, Vachier I, Roux S, Loubatiere J et al: HLA-DR and ICAM-1 expression on bronchial epithelial cells in asthma and chronic bronchitis. Am Rev Respir Dis 1993, 148(3):689-694.