Analysis of gene expressions of T cells from children with acute exacerbations of asthma

International Archives of Allergy and Immunology

Volumn 134, Issue 1, 2004, Pages 29-33

  Katsunuma, Toshio ^a   Kawahara, Hidetoshi ^b   Suda, Tomoko ^b   Ishii, Tetsuji ^b   Ohya, Yukihiro ^b   Akasawa, Akira ^b   Saito, Hirohisa ^c   Oshida, Tadahiro ^d   Sugita, Yuji ^d  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CHILDREN S HOSPITAL   (Japan)

^c NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^d Genox Research Inc   (Japan)

Author keywords

Asthma, childhood; Interleukin 4; Lipocortin II (annexin II); Rt pcr, differential display

Indexed keywords

ALPHA6 INTEGRIN; GAMMA INTERFERON; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 12 RECEPTOR BETA; INTERLEUKIN 4; INTERLEUKIN 5; LIPOCORTIN 2; MESSENGER RNA; RNA; UNCLASSIFIED DRUG;

ARTICLE; ASTHMA; BLOOD LEVEL; CELL ISOLATION; CHILD; CLINICAL ARTICLE; DIFFERENTIAL DISPLAY; DISEASE EXACERBATION; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; MALE; PRIORITY JOURNAL; REMISSION; RESPIRATORY TRACT DISEASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; T LYMPHOCYTE;

ACUTE DISEASE; ANNEXIN A2; ASTHMA; CHILD; CHILD WELFARE; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFLAMMATION MEDIATORS; INTEGRIN ALPHA6; INTERFERON TYPE II; INTERLEUKIN-4; INTERLEUKIN-5; MALE; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-12; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 2542555049     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000077530     Document Type: Article

References (18)

1. Davies DE, Wicks J, Powell RM, Puddicombe SM, Holgate ST: Airway remodeling in asthma: New insights. J Allergy Clin Immunol 2003;111:215-225.
2. Chedevergne F, Le Bourgeois M, de Blic J, Scheinmann P: The role of inflammation in childhood asthma. Arch Dis Child 2000;82(suppl 2):ii6-ii9.
3. Azzawi M, Bradley B, Jeffery PK, Frew AJ, Wardlaw AJ, Knowles G, Assoufi B, Collins JV, Durham S, Kay AB: Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis 1990;142/6/1:1407-1413.
4. Wood DW, Downes JJ, Lecks HI: A clinical scoring system for the diagnosis of respiratory failure. Am J Dis Child 1972;123:227-228.
5. Ito T, Kito K, Adati N, Mitsui Y, Hagiwara H, Sakaki Y: Fluorescent differential display: Arbitrarily primed RT-PCR fingerprinting on an automated DNA sequencer. FEBS Lett 1994;351/2:231-236.
6. Ali M, Markham AF, Isaacs JD: Application of differential display to immunological research. J Immunol Methods 2001;250/1-2:29-43.
7. Fryer RM, Randall J, Yoshida T, Hsiao LL, Blumenstock J, Jensen KE, Dimofte T, Jensen RV, Gullans SR: Global analysis of gene expression: Methods, interpretation, and pitfalls. Exp Nephrol 2002;10/2:64-74.
8. Dubois T, Oudinet JP, Russo-Marie F, Rothhut B: In vivo and in vitro phosphorylation of annexin II in T cells: Potential regulation by annexin V. Biochem J 1995;310/1:243-248.
9. Corvera S, DiBonaventura C, Shpetner HS: Cell confluence-dependent remodeling of endothelial membranes mediated by cholesterol. J Biol Chem 2000;275:31414-31421.
10. Falcone DJ, Borth W, Khan KM, Hajjar KA: Plasminogen-mediated matrix invasion and degradation by macrophages is dependent on surface expression of annexin II. Blood 2001;97:777-784.
11. Kang HM, Choi KS, Kassam G, Fitzpatrick SL, Kwon M, Waisman DM: Role of annexin II tetramer in plasminogen activation. Trends Cardiovasc Med 1999;9:92-102.
12. Benevolensky D, Belikova Y, Mohammadzadeh R, Trouve P, Marotte F, Russo-Marie F, Samuel JL, Charlemagne D: Expression and localization of the annexins II, V, and VI in myocardium from patients with end-stage heart failure. Lab Invest 2000;80:123-133.
13. Litonjua AA, Sparrow D, Guevarra L, O'Connor GT, Weiss ST, Tollerud DJ: Serum interferon-γ is associated with longitudinal decline in lung function among asthmatic patients: The normative aging study. Ann Allergy Asthma Immunol 2003;90:422-428.
14. Robinson DS, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley AM, Corrigan C, Durham SR, Kay AB: Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298-304.
15. Bentley AM, Hamid Q, Robinson DS, Schotman E, Meng Q, Assoufi B, Kay AB, Durham SR: Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa. Am J Respir Crit Care Med 1996;153:551-556.
16. Humbert M, Durham SR, Ying S, Kimmitt P, Barkans J, Assoufi B, Pfister R, Menz G, Robinson DS, Kay AB, Corrigan CJ: IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: Evidence against 'intrinsic' asthma being a distinct immunopathologic entity. Am J Respir Crit Care Med 1996;154:1497-1504.
17. Ying S, Humbert M, Barkans J, Corrigan CJ, Pfister R, Menz G, Larche M, Robinson DS, Durham SR, Kay AB: Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics. J Immunol 1997;158:3539-3544.
18. Krug N, Jung T, Napp U, Wagner K, Schultze-Werninghaus G, Heusser C, Rieger CH, Schauer U, Fabel H: Frequencies of T cells expressing interleukin-4 and interleukin-5 in atopic asthmatic children. Comparison with atopic asthmatic adults. Am J Respir Crit Care Med 1998;158:754-759.