Apoptosis induction and inhibition of H-ras overexpression by novel trans-[PtCl2(isopropylamine)(amine')] complexes

Journal of Inorganic Biochemistry

Volumn 77, Issue 1-2, 1999, Pages 37-42

  Perez J M ^a   Montero, E I ^a   Gonzalez A M ^a   Alvarez Valdes A ^a   Alonso, C ^a   Navarro Ranninger, C ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Apoptosis; Cisplatin; H ras oncogene

Indexed keywords

CISPLATIN; TRANSPLATIN; TRANSPLATIN(ISOPROPYLAMINE)BUTYLAMINE; TRANSPLATIN(ISOPROPYLAMINE)DIMETHYLAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; COMPLEX FORMATION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TRANSFORMED; CELLS, CULTURED; CISPLATIN; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; KERATINOCYTES; MICE; ONCOGENE PROTEIN P21(RAS); ORGANOPLATINUM COMPOUNDS;

EID: 2542509970     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-0134(99)00143-9     Document Type: Article

References (20)

1. Farrell N. Met. Ions Biol. Syst. 32:1996;603-639.
2. Coluccia M., Nassi A., Loseto F., Boccarelli A., Mariggiò M.A., Giordano D., Intini F.P., Caputo P., Natile G. J. Med. Chem. 36:1993;510-512.
3. Coluccia M., Boccarelli A., Mariggiò M.A., Cardellichio N., Caputo P., Intini F.P., Natile G. J. Chem. Biol. Interact. 22:1995;251-266.
4. Kelland L.R. Crit. Rev. Oncol. Hematol. 15:1993;191-219.
5. O'Neill C.F., Ormerod M.G., Robertson D., Titley J.C., Cumber-Walsweer Y., Kelland L.R. Br. J. Cancer. 74:1996;1037-1045.
6. Montero E.I., Díaz S., González-Vadillo A.M., Pérez J.M., Alonso C., Navarro-Ranniger C. J. Med. Chem. 42:1999;4264-4268.
7. Missero C., Ramón y Cajal S., Dotto G.P. Proc. Natl. Acad. Sci. USA. 88:1991;1295-1300.
8. Florin-Christensen M., Missero C., Florin J., Tranque P., Ramón y Cajal S., Dotto G.P. Exp. Cell Res. 207:1993;57-61.
9. Sánchez-Prieto R., Vargas J.A., Carnero A., Marchetti E., Romero J., Durantez A., Lacal J.C., Ramón y Cajal S. Int. J. Cancer. 60:1995;235-243.
10. Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R. Cancer Res. 48:1998;589-601.
11. Pérez J.M., Camazón M., Alvarez-Valdés A., Quiroga A.G., Kelland L.R., Alonso C., Navarro-Ranninger C. Chem.-Biol. Interact. 117:1999;99-115.
12. Jacobson M.D., Burne J.F., King M.P., Miyashita T., Reed J.C., Raff M.C. Nature. 361:1993;365-369.
13. Lowe S.W., Earl Ruley H., Jacks T., Housman D.E. Cell. 74:1993;957-967.
14. Jones N.A., Turner J., McIlwrath A.J., Brown R., Dive C. Mol. Pharmacol. 53:1998;819-826.
15. Pérez J.M., Quiroga A.G., Montero E.I., Alonso C., Navarro-Ranninger C. J. Inorg. Biochem. 73:1999;235-243.
16. Banerjee F.J., Stambrook P.J., Bertino J.R. Biochem. Pharmacol. 53:1997;1203-1209.
17. Skalr M.D. Cancer Res. 48:1988;793-797.
18. Banerjee F.J., Stambrook P.J., Bertino J.R. Biochem. Pharmacol. 53:1997;1203-1209.
19. Farrell N. Cancer Invest. 11:1993;578-589.
20. Brabec V., Vrana O., Novakova V., Kleinwachter V., Intini F.P., Coluccia M., Natile G. Nucleic Acids Res. 24:1996;336-341.