First trimester human endovascular trophoblast cells express both HLA-C and HLA-G

American Journal of Reproductive Immunology

Volumn 42, Issue 1, 1999, Pages 30-36

  Pröll, Johannes ^a   Blaschitz, Astrid ^a   Hutter, Heinz ^a   Dohr, Gottfried ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

Endovascular trophoblast; HLA class I; Human first trimester placenta; Spiral arteries

Indexed keywords

HLA C ANTIGEN; HLA G ANTIGEN;

CONFERENCE PAPER; DECIDUA; FEMALE; FETUS; FIRST TRIMESTER PREGNANCY; HLA SYSTEM; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MATERNAL BLOOD; PRIORITY JOURNAL; SYNCYTIOTROPHOBLAST; TROPHOBLAST;

EID: 2542508514     PISSN: 10467408     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0897.1999.tb00462.x     Document Type: Conference Paper

References (44)

1. Le Bouteiller P: HLA class I chromosomal region, genes, and products: Facts and questions. Crit Rev Immunol 1994; 14:89-129.
2. Hutter H, Hammer A, Blaschitz A, Hartmann M, Ebbesen P, Dohr G, Ziegler A, Uchanska-Ziegler B: Expression of HLA class I molecules in human first trimester and term placenta trophoblast. Cell Tissue Res 1996; 286:439-447.
3. King A, Boocock C, Sharkey AM, Gardner L, Beretta A, Siccardi AG, Loke YW: Evidence for the expression of HLA-C class I mRNA and protein by human first trimester trophoblast. J Immunol 1996; 156:2068-2076.
4. Blankenship TN, Enders AC, King BF: Trophoblastic invasion and the development of uteroplacental arteries in the macaque: Immunohistochemical localization of cytokeratins, desmin, type IV collagen, laminin, and fibronectin. Cell Tissue Res 1993; 272:227-236.
5. Burrows TD, King A, Loke YW: Expression of adhesion molecules by endovascular trophoblast and decidual endothelial cells: Implications for vascular invasion during implantation. Placenta 1994; 15:21-33.
6. Nanaev A, Chwalisz K, Frank HG, Kohnen G, Hegele-Hartung C, Kaufmann P: Physiological dilation of uteroplacental arteries in the guinea pig depends on nitric oxide synthase activity of extravillous trophoblast. Cell Tissue Res 1995; 282:407-421.
7. Pröll J, Blaschitz A, Hartmann M, Thalhamer J, Dohr G: Cytokeratin 17 as an immunohistochemical marker for intramural cytotrophoblast in human first trimester uteroplacental arteries. Cell Tissue Res 1997; 288:335-343.
8. Hartmann M, Blaschitz A, Hammer A, Haidacher S, Mahnert W, Watcher W, Dohr G: Immunohistochemical examination of trophoblast populations in human first trimester and term placentae and of first trimester spiral arteries with the monoclonal antibody GZ 112. Placenta 1997; 18:481-489.
9. Damsky CH, Librach C, Lim KH, Fitzgerald ML, McMaster MT, Janatpour M, Zhou Y, Logan SK, Fisher SJ: Integrin switching regulates normal trophoblast invasion. Development 1994; 120:3657-3666.
10. Pröll J, Blaschitz A, Hartmann M, Thalhamer J, Dohr G: Human first trimester placenta intra-arterial trophoblast cells express the neural cell adhesion molecule. Early Pregnancy 1996; 2:217-275.
11. Zhou Y, Fisher SJ, Janatpour M, Genbacev O, Dejana E, Wheelock M, Damsky CH: Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion? J Clin Invest 1997; 99:2139-2151.
12. Zhou Y, Damsky CH, Fisher SJ: Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome? J Clin Invest 1997; 99:2152-2164.
13. Barnstable CJ, Bodmer WF, Brown G, Galfre G, Milstein C, Williams AF, Ziegler A: Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens - new tools for genetic analysis. Cell 1978; 14:9-20.
14. Uchanska-Ziegler B, Nossner E, Schenk A, Ziegler A, Schendel DJ: Soluble T cell receptor-like properties of an HLA-B35-specific monoclonal antibody (TU165). Eur J Immunol 1993; 23:734-738.
15. Damjanovich S, Vereb G, Schaper A, Jenei A, Matko J, Starink JP, Fox GQ, Arndt-Jovin DJ, Jovin DJ, Jovin TM: Structural hierarchy in the clustering of HLA class I molecules in the plasma membrane of human lymphoblastoid cells. Proc Natl Acad Sci USA 1995; 92:1122-1126.
16. Lemonnier FA, Le Bouteiller P, Malissen B, Golstein P, Malissen M, Mishal Z, Caillol DH, Jordan BR, Kourilsky FM: Transformation of murine LMTK- cells with purified HLA class I genes. I. Modification of conformation of murine beta 2-microglobulin upon its association with HLA heavy chains. J Immunol 1983; 130:1432-1438.
17. Stam NJ, Spits H, Ploegh HL: Monoclonal antibodies raised against denatured HLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products. J Immunol 1986; 137:2299-2306.
18. Giacomini P, Beretta A, Nicotra MR, Ciccarelli G, Martayan A, Cerboni C, Lopalco L, Bini D, Delino L, Ferrara GB, Siccardi AG, Natali PG: HLA-C heavy chains free of β2-microglobulin: Distribution in normal tissues and neoplastic lesions of non-lymphoid origin and interferon-γ responsiveness. Tissue Antigens 1997; 50:555-566.
19. Schnabel E, Stockinger H, Maydic O, Gaugitsch H, Lindley IJ, Maurer D, Hajek-Rosenmayr A, Knapp W: Activated human T lymphocytes express MHC class I heavy chains not associated with beta 2-microglobulin. J Exp Med 1990; 171:1431-1442.
20. Stam NJ, Vroom TM, Peters PJ, Pastoors EB, Ploegh HL: HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy. Int Immunol 1990; 2:113-125.
21. Odum N, Ledbetter JA, Martin P, Geraghty D, Tsu T, Hansen JA, Gladstone P: Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies. Eur J Immunol 1991; 21:2121-2131.
22. Loke YW, King A, Burrows T, Gardner L, Bowen M, Hilby S, Hewlett S, Holmes N, Jacobs D: Evaluation of trophoblast HLA-G antigen with a specific monoclonal antibody. Tissue Antigens 1997; 50:135-146.
23. Bensussan A, Mansur IG, Mallet V, Rodriguez AM, Girr M, Weiss EH, Brem G, Boumsell L, Gluckman E, Dausset J, Carosella E, Le Bouteiller P: Detection of membrane-bound HLA-G translated products with a specific monoclonal antibody. Proc Natl Acad Sci USA 1995; 92:10292-10296.
24. Lee N, Malacko AR, Ishitani A, Chen MC, Bajorath J, Marquardt H, Geraghty DE: The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association. Immunity 1995; 3:591-600.
25. Daya D, Sabet L: The use of cytokeratin as a sensitive and reliable marker for trophoblastic tissue. Am J Clin Pathol 1991; 95:137-141.
26. Blaschitz A, Lenfant F, Mallet V, Hartmann M, Bensussan A, Geraghty DE, Le Bouteiller P, Dohr G: Endothelial cells in chorionic fetal vessels of first trimester placenta express HLA-G. Eur J Immunol 1997; 27:3380-3388.
27. Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, Svejeaard A, Terasaki PI: Nomenclature for factors of the HLA System, 1996. Hum Immunol 1997; 53:98-128.
28. Singer DS, Maguire JE: Regulation of the expression of class I MHC genes. Crit Rev Immunol 1990; 10:235-257.
29. Srivastava R, Lambert ME: Molecular organization and expression of class I HLA gene family. In Immunogenetics of the Major Histocompatibility Complex, R Srivastava, BP Ram, P Tyle (eds). New York, VCH Publishers, 1991, p. 100.
30. Reinhardt C, Falk C, Steinle A, Schendel DJ: MHC class I allorecognition: The likes and dislikes of CTL and NK cells. Behring Inst Mitt 1994; 94:61-71.
31. Falk CS, Steinle A, Schendel DJ: Expression of HLA-C molecules confers target cell resistance to some non-major histocompatibility complex-restricted T cells in a manner analogous to allospecific natural killer cells. J Exp Med 1995; 182:1005-1018.
32. Colonna M, Borsellino G, Falco M, Ferrara GB, Strominaer JL: HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells. Proc Natl Acad Sci USA 1993; 90:12000-12004.
33. Bishara A, Amar A, Brautbar C, Condiotti R, Lazarovitz V, Nagler A: The putative role of HLA-C recognition in graft versus host disease (GVHD) and graft rejection after unrelated bone marrow transplantation (BMT). Exp Hematol 1995; 23:1667-1675.
34. Grundschober C, Rufer N, Sanchez-Mazas A, Madrigal A, Jeannet M, Roosnek E, Tiercy JM: Molecular characterization of HLA-C incompatibilities in HLA-ABDR-matched unrelated bone marrow donor-recipient pairs. Sequence of two new Cw alleles (Cw*02023 and Cw*0707) and recognition by cytotoxic T lymphocytes. Tissue Antigens 1997; 49:612-623.
35. Matzinger P: Tolerance, danger and the extended family. Ann Rev Immunol 1994; 12:991-1045.
36. Mackay CR, Imhof BA: Cell adhesion in the immune system. Immunol Today 1993; 14:99-102.
37. Kündig TM, Bachmann MF, Oehen S, Hoffmann UW, Simard JJ, Kalberer CP, Pircher H, Ohashi PS, Hengartner H, Zinkernagel RM: On the role of antigen in maintaining cytotoxic T-cell memory. Proc Natl Acad Sci USA 1996; 93:9716-9723.
38. Chumberley G, King A, Robertson K, Holmes N, Loke YW: Resistance of HLA-G and HLA-A2 transfectants to lysis by decidual NK cells. Cell Immunol 1994; 155:312-322.
39. Rouas-Freiss N, Marchai RE, Kirszenbaum M, Dausset J, Carosella ED: The al domain of HLA-G1 and HLA-G2 inhibits cytotoxicity induced by natural killer cells: Is HLA-G the public ligand for natural killer cell inhibitory receptors? Proc Natl Acad Sci USA 1997; 94:5249-5254.
40. Ishitani A, Geraghty DE: Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens. Proc Natl Acad Sci USA 1992; 89:3947-3951.
41. Fujii T, Ishitani A, Geraghty DE: A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4. J Immunol 1994; 153:5516-5524.
42. Kirszenbaum M, Moreau P, Gluckman E, Dausset J, Carosella E: An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes. Proc Natl Acad Sci USA 1994; 91:4209-4213.
43. Kovats S, Main EK, Librach C, Stubblebine M, Fisher SJ, DeMars R: Expression and possible function of the HLA-G α chain in human cytotrophoblast. In Cellular and Molecular Biology of the Materno-Fetal Relationship, Vol. 212, G Chaouat, J Mowbray (eds). Paris, Colloque INSERM/John Libbey Eurotext Ltd, 1991.
44. Chu W, Fant ME, Geraghty DE, Hunt JS: Soluble HLA-G in human placentas: Synthesis in trophoblasts and interferon-gamma-activated macrophages but not placental fibroblasts. Hum Immunol 1998; 59:435-442.