Time-of-flight secondary ion mass spectrometry can replace histochemistry demonstration of fatty acids in the retina

Japanese Journal of Ophthalmology

Volumn 48, Issue 3, 2004, Pages 287-293

  Amemiya, Tsugio ^a   Tozu, Miyako ^b   Ohashi, Yoshiharu ^b  

^a NAGASAKI UNIVERSITY   (Japan)

^b ULVAC PHI Inc   (Japan)

Author keywords

Fatty acids; Histochemistry; Retina; Time of flight secondary ion mass spectrometry

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; FATTY ACID; LIQUID NITROGEN; MALEIC ACID; OLEIC ACID; PALMITIC ACID; PENTOBARBITAL; SILICON; STEARIC ACID;

AIR; ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CALCULATION; CONTROLLED STUDY; ENUCLEATION; HISTOCHEMISTRY; MOLECULAR WEIGHT; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RAT; RAT STRAIN; RETINA; TIME OF FLIGHT MASS SPECTROMETRY; TISSUE SLICE;

ANIMALS; FATTY ACIDS; HISTOCYTOCHEMISTRY; PHOTORECEPTORS; RATS; RATS, INBRED WKY; RETINA; SPECTROMETRY, MASS, SECONDARY ION;

EID: 2542487542     PISSN: 00215155     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10384-003-0062-7     Document Type: Article

References (36)

1. Kulkarni P, Cai J, Hurst HE. Lipids and nitric oxide in porcine retinal and choroidal blood vessels. J Ocul Pharmacol Ther 2002;18:265-275.
2. Sellner PA, Clough JA. Fatty acid composition of phospholipids from chick neural retina during development. Exp Eye Res 1992;54:725-730.
3. Bazan HE, Bazan NG, Feeney-Burns L, Berman ER. Lipids in human lipofuscin-enriched subcellular fractions of two age populations. Comparison with rod outer segments and neural retina. Invest Ophthalmol Vis Sci 1990;31:1433-1443.
4. Cagianut B, Sandri G, Zilla P, Theiler K. Studies on hereditary retinal degeneration. The rd gene in the mouse. Graefes Arch Clin Exp Ophthalmol 1985;223:16-22.
5. Nourooz-Zadeh J, Pereira P. Age-related accumulation of free polyunsaturated fatty acids in human retina. Ophthalmic Res 1999;31:273-279.
6. Wiegand RD, Joel CD, Rapp LM, et al. Polyunsaturated fatty acids and vitamin E in rat rod outer segments during light damage. Invest Ophthalmol Vis Sci 1986;27:727-733.
7. Linton RW, Goldsmith JG. The role of secondary ion mass spectrometry (SIMS) in biological microanalysis: technique comparisons and prospects. Biol Cell 1992;74:147-160.
8. Oba K, Gong H, Amemiya T, Baba K, Takaya K. Applying secondary ion mass spectrometry to the analysis of elements in goblet cells of conjunctiva. J Electron Microsc 2001;50:325-332.
9. Ausserer WA, Chandra S, Morrison GH. Morphological and elemental integrity of freeze-fractured, freeze-dried cultured cells during ion microscopic analysis. J Microsc 1989;154 (Pt 1):39-57.
10. Hatchinson TH, Somlym AP. Microprobe analysis of biological systems. New York: Academic Press; 1981.
11. Burns MS. Applications of secondary ion mass spectrometry (SIMS) in biological research: a review. J Microsc 1982;127(Pt 3):237-258.
12. Galle P, Escaig F, Dantin F, Zhang L. Mapping the subcellular distribution of biomolecules at the ultrastructural level by ion microscopy. Cell Mol Biol 1996;42:325-334.
13. Fragu P, Briancon C, Fourre C, et al. SIMS microscopy in the biomedical field. Biol Cell 1992;74:5-18.
14. Hill R. Primary ion beam systems. In: Vickerman JC, Briggs D, editors. ToF-SIMS: surface analysis by mass spectrometry. West Sussex: IM; 2001. p. 95-111.
15. Schueler BW. Time-of-Flight mass analysers. In: Vickerman JC, Briggs D, editors. ToF-SIMS: surface analysis by mass spectrometry. West Sussex: IM; 2001. p. 75-94.
16. Fragu P, Clerc J, Briancon C, et al. Recent developments in medical applications of SIMS microscopy. Micron 1994;25:361-370.
17. Vickerman JC. ToF-SIMS: an overview. In: Vickerman JC, Briggs D, editors. ToF-SIMS: surface analysis by mass spectrometry. West Sussex: IM; 2001. p. 1-40.
18. Jabs HU, Assmann G, Greifendorf D, Benninghoven A. High performance liquid chromatography and time-of-flight secondary ion mass spectrometry: a new dimension in structural analysis of apolipoproteins. J Lipid Res 1986;27:613-621.
19. Pacholski ML, Cannon DM Jr, Ewing AG, Winograd N. Static time-of-flight secondary ion mass spectrometry imaging of freeze-fractured, frozen-hydrated biological membranes. Rapid Commun Mass Spectrom 1998;12:1232-1235.
20. Clerc J, Fourre C, Fragu P. SIMS microscopy: methodology, problems and perspectives in mapping drugs and nuclear medicine compounds. Cell Biol Int 1997;21:619-633.
21. Cullen P, Fobker M, Tegelkamp K, et al. An improved method for quantification of cholesterol and cholesteryl esters in human monocyte-derived macrophages by high performance liquid chromatography with identification of unassigned cholesteryl ester species by means of secondary ion mass spectrometry. J Lipid Res 1997;38:401-409.
22. Mony MC, Larras-Regard E. Imaging of subcellular structures by scanning ion microscopy and mass spectrometry. Advantage of cryofixation and freeze substitution procedure over chemical preparation. Biol Cell 1997;89:199-210.
23. Lowry OH, Roberts NR, Lewis C. The quantitative histochemistry of the retina. J Biol Chem 1956;220:879-892.
24. Fliesler SJ, Schroepfer GJ Jr. Sterol composition of bovine retinal rod outer segment membranes and whole retinas. Biochim Biophys Acta 1982;711:138-148.
25. Bazan NG, Reddy TS, Redmond TM, Wiggert B, Chader GJ. Endogenous fatty acids are covalently and noncovalently bound to interphotoreceptor retinoid-binding protein in the monkey retina. J Biol Chem 1985;260:13677-13680.
26. Anderson RE, Maude MB, Zimmerman W. Lipids of ocular tissues. X. Lipid composition of subcellular fractions of bovine retina. Vision Res 1975;15:1087-1090.
27. Bergman ER. Biochemistry of the eye. New York: Plenum; 1991. p. 343-345.
28. Chandra S, Morrison GH. Sample preparation of animal tissues and cell cultures for secondary ion mass spectrometry (SIMS) microscopy. Biol Cell 1992;74:31-42.
29. Reddy TS, Birkle DL, Armstrong D, Bazan NG. Change in content, incorporation and lipoxygenation of docosahexaenoic acid in retina and retinal pigment epithelium in canine ceroid lipofuscinosis. Neurosci Lett 1985;59:67-72.
30. Reddy TS, Bazan NG. Synthesis of docosahexaenoyl-, arachidonoyl- and palmitoyl-coenzyme A in ocular tissues. Exp Eye Res 1985;41:87-95.
31. Fliesler SJ, Anderson RE. Chemistry and metabolism of lipids in the vertebrate retina. Prog Lipid Res 1983;22:79-131.
32. Rotstein NP, Aveldano MI. Labeling of lipids of retina subcellular fractions by [1-14C] eicosatetraenoate [20:4(n-6)] docosapentaenoate [22:5(n-3)] and docosahexaenoate [22:6(n-3)]. Biochim Biophys Acta 1987;921:221-234.
33. Amemiya T, Gong H, Takaya K, Tozu M, Ohashi Y. Changes of vitamin A and E in the rat under light and dark conditions detected with TOF-SIMS. Appl Surf Sci 2003;203-204:738-741.
34. Gong H, Amemiya T, Takaya K. Retinal changes in magnesium-deficient rats. Exp Eye Res 2001;72:23-32.
35. Kinoshita A, Gong H, Amemiya T, Takaya K, Tozu M, Ohashi Y. Trace elements in lenses of normal Wistar Kyoto rats. Appl Surf Sci 2003;203-204:742-744.
36. Kishikawa Y, Gong H, Kitaoka T, et al. Elements and organic substances in epiretinal proliferative tissue excised during vitreous surgery: analysis by time-of-flight secondary-ion mass spectrometry. J Electron Microsc 2003;52:349-354.