Gas exchange responses to constant work-rate exercise in patients with glycogenosis type V and VII

American Journal of Respiratory and Critical Care Medicine

Volumn 169, Issue 11, 2004, Pages 1238-1244

  Ong, Hean Yee ^b   O'Dochartaigh, Conor S ^b   Lovell, Sharon ^b   Patterson, Victor H ^b   Wasserman, Karlman ^b   Paul Nicholls, D ^b   Riley, Marshall S ^a  

^a BELFAST CITY HOSPITAL   (United Kingdom)

^b NONE

Author keywords

Acidosis, lactic; Exercise; Glycogen storage disease; Oxygen consumption

Indexed keywords

6 PHOSPHOFRUCTOKINASE; LACTIC ACID;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EXERCISE TEST; FEMALE; GAS EXCHANGE; GLYCOGEN STORAGE DISEASE TYPE 5; GLYCOGEN STORAGE DISEASE TYPE 7; HUMAN; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RANK SUM TEST; STEADY STATE;

EID: 2542476180     PISSN: 00030805     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200307-974oc     Document Type: Article

References (48)

1. Wasserman K, Whipp BJ, Koyal SN, Beaver WL. Anaerobic threshold and respiratory gas exchange during exercise. J Appl Physiol 1973;35: 236-243.
2. Whipp BJ, Wasserman K. Oxygen uptake kinetics for various intensities of constant-load work. J Appl Physiol 1972;33:351-356.
3. Poole DC, Schaffartzik W, Knight DR, Derion T, Kennedy B, Guy HJ, Prediletto R, Wagner PD. Contribution of excising legs to the slow component of oxygen uptake kinetics in humans. J Appl Physiol 1991; 71:1245-1260.
4. Riley MS, Cooper CB. Ventilatory and gas exchange responses during heavy constant work-rate exercise. Med Sci Sports Exerc 2002;34:98-104.
5. Riley MS, Pórszász J, Engelen MP, Shapiro SM, Brundage BH, Wasserman K. Responses to constant work rate bicycle ergometry exercise in primary pulmonary hypertension: the effect of inhaled nitric oxide. J Am Coll Cardiol 2000;36:547-556.
6. Otsuka T, Kurihara N, Fujii T, Fujimoto S, Yoshikawa J. Effect of exercise training and detraining on gas exchange kinetics in patients with chronic obstructive pulmonary disease. Clin Physiol 1997;17:287-297.
7. Casaburi R, Porszasz J, Burns MR, Carithers ER, Chang RSY, Cooper CB. Physiologic benefits of exercise training in rehabilitation of patients with severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1997;155:1541-1551.
8. 2 uptake kinetics in response to exercise: a measure of tissue anaerobiosis in heart failure. Chest 1993;103:735-741.
9. Roston WL, Whipp BJ, Davis JA, Cunningham DA, Effros RM, Wasserman K. Oxygen uptake kinetics and lactate concentration during exercise in humans. Am Rev Respir Dis 1987;135:1080-1084.
10. Poole DC, Ward SA, Gardner GW, Whipp BJ. Metabolic and respiratory profile of the upper limit for prolonged exercise in man. Ergonomics 1988;31:1265-1279.
11. Gollnick PD, Hermansen L. Biochemical adaptation to exercise: anaerobic metabolism. In: Wilmore JH, editor. Exercise and sports sciences reviews. New York: Academic Press; 1973. p. 1-43.
12. Talmadge RJ, Scheide JI, Silverman H. Glycogen synthesis from lactate in a chronically active muscle. J Appl Physiol 1989;66:2231-2238.
13. Poortmans JR, Delescaille-Vanden Bossche J, Leclercq R. Lactate uptake by inactive forearm during progressive leg exercise. J Appl Physiol 1978;45:1581-1586.
14. Gladden LB. Net lactate uptake during progressive steady-level contractions in canine skeletal muscle. J Appl Physiol 1991;71:514-520.
15. Wasserman K, Hansen JE, Sue DY. Facilitation of oxygen consumption by lactic acidosis during exercise. News Physiol Sci 1991;6:29-34.
16. McArdle B. Myopathy due to a defect in muscle glycogen breakdown. Clin Sci 1951;10:13-18.
17. Schmid R, Mahler R. Chronic progressive myopathy and myoglobinuria- demonstration of a glycogenolytic defect in muscle. J Clin Invest 1959; 38:2044-2058.
18. Mommaerts WFHM, Ilingworth B, Pearson CM. A functional disorder of muscle associated with the absence of phosporylase. Proc Natl Acad Sci USA 1959;45:791-797.
19. Lewis SF, Haller RG, Cook JD, Blomqvist CG. Metabolic control of cardiac output response to exercise in McArdle's disease. J Appl Physiol 1984;57:1749-1753.
20. Riley M, Nicholls DP, Nugent AM, Steele IC, Bell N, Davies PM, Stanford CF, Patterson VH. Respiratory gas exchange and metabolic responses during exercise in McArdle's disease. J Appl Physiol 1993;75: 745-754.
21. Tarui S, Kono N, Nasu T, Nishikawa M. Enzymatic basis for the coexistence of myopathy and hemolytic disease in inherited muscle phosphofructokinase deficiency. Biochem Biophys Res Commun 1969;34:77-83.
22. Ong HY, O'Dochartaigh C, Lovell S, Riley MS, Nicholls DP. Rise in oxygen consumption during high intensity constant work rate exercise in patients with McArdle's disease [abstract]. Eur J Clin Invest 2000; 30:4.
23. Buchfuhrer ML, Hansen JE, Robinson TE, Sue DY, Wasserman K, Whipp BJ. Optimizing the exercise protocol for cardiopulmonary assessment. J Appl Physiol 1983;55:1558-1564.
24. Beaver WL, Lamarra N, Wasserman K. Breath-by-breath measurement of true alveolar gas exchange. J Appl Physiol 1981;51:1662-1675.
25. Beaver WL, Wasserman K, Whipp BJ. A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 1986;60:2020-2027.
26. Maehara K, Riley M, Galassetti P, Barstow TJ, Wasserman K. Effect of hypoxia and carbon monoxide on muscle oxygenation during exercise. Am J Respir Crit Care Med 1997;155:229-235.
27. 2 during heavy exercise. J Appl Physiol 1987;62:199-207.
28. Poole DC, Ward SA, Whipp BJ. The effects of training on the metabolic and respiratory profile of high-intensity cycle ergometer exercise. Eur J Appl Physiol 1990;59:421-429.
29. Ryan WJ, Sutton WJ, Toews CJ, Jones NL. Metabolism of infused L(+) lactate during exercise. Clin Sci 1979;56:139-146.
30. 2 slow component. J Appl Physiol 1994;76:787-792.
31. 2 uptake kinetics during heavy exercise in humans. J Appl Physiol 1994;77:2413-2419.
32. 2 slow component: physiological and functional significance. Med Sci Sports Exerc 1994;26:1354-1358.
33. 2 uptake between the on- and off-transients of moderate- and high-intensity exercise in humans. J Physiol 2002;541:991-1002.
34. 2 uptake and heart rate kinetics during heavy exercise. J Appl Physiol 1996;81:2500-2508.
35. Willis WT, Jackman MR. Mitochondrial function during heavy exercise. Med Sci Sports Exerc 1994;26:1347-1353.
36. Koga S, Shiojiri T, Kondo N, Barstow TJ. Effect of increased muscle temperature on oxygen uptake kinetics during exercise. J Appl Physiol 1997;83:1333-1338.
37. Lovell SL, Maguire SM, Turtle F, McDowell G, Campbell NPS, Riley MS, Nicholls DP. Comparative physiological study of arbutamine with exercise in humans. Clin Sci 2000;98:489-494.
38. Saltin B. Muscle fibre recruitment and metabolism in prolonged exhaustive dynamic exercise. Ciba Found Symp 1981;82:41-58.
39. Barstow TJ, Jones AM, Nguyen PH, Casaburi R. Influence of muscle fiber type and pedal frequency on oxygen uptake kinetics of heavy exercise. J Appl Physiol 1996;81:1642-1650.
40. 2 slow component for severe exercise depends on type of exercise and is not correlated with time to fatigue. J Appl Physiol 1998;85:2118-2124.
41. Carter H, Jones AM, Barstow TJ, Burnley M, Williams C, Doust JH. Oxygen uptake kinetics in treadmill running and cycle ergometry: a comparison. J Appl Physiol 2000;89:899-907.
42. Saunders MJ, Evans EM, Arngrimsson SA, Allison JD, Warren GL, Cureton KJ. Muscle activation and the slow component rise in oxygen uptake during cycling. Med Sci Sports Exerc 2000;32:2040-2045.
43. 2 slow component dependent on progressive recruitment of fast-twitch fibers in trained runners? J Appl Physiol 2001;90:2212-2220.
44. Pringle JSM, Doust JH, Carter H, Tolfrey K, Jones AM. Effect of pedal rate on primary and slow-component oxygen uptake responses during heavy-cycle exercise. J Appl Physiol 2003;94:1501-1507.
45. Stringer W, Wasserman K, Casaburi R, Pórszász J, Maehara K, French W. Lactic acidosis as a facilitator of oxyhemoglobin dissociation during exercise. J Appl Physiol 1994;76:1462-1467.
46. Koike A, Wasserman K, Taniguchi K, Hiroe M, Marumo F. Critical capillary oxygen partial pressure and lactate threshold in patients with cardiovascular disease. J Am Coll Cordial 1994;23:1640-1650.
47. O'Dochartaigh C, Ong HY, Lovell S, Riley MS, Nicholls DP. Physiological responses to incremental exercise in McArdle's disease. Am J Respir Crit Care Med 2001;163:A20. (abstract).
48. Haller RG, Lewis SF, Cook JD, Blomqvist CG. Hyperkinetic circulation during exercise in neuromuscular disease. Neurology 1983;33:1283-1287.