Two simple and different approaches to the synthesis of new 2,4-dialkylamino substituted 6,7-dihydro-5H-benzocyclohepta[1,2-d]pyrimidines

Tetrahedron

Volumn 60, Issue 25, 2004, Pages 5475-5479

  Herrera, Antonio ^a   Martínez Álvarez, Roberto ^a   Chioua, Rachid ^a,b   Benabdelouahab, Fouad ^b   Chioua, Mourad ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b FACULTÉ DES SCIENCES   (Morocco)

Author keywords

1 Benzosuberone; Benzocycloheptapyrimidines; Cyanamides; Triflic anhydride

Indexed keywords

6,7 DIHYDRO 5H BENZOCYCLOHEPTA[1,2 D]PYRIMIDINE DERIVATIVE; AMINE; ANTIDEPRESSANT AGENT; ANTITHROMBOCYTIC AGENT; CYANAMIDE; MESYLIC ACID DERIVATIVE; PYRIMIDINE DERIVATIVE; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL; REACTION ANALYSIS; SUBSTITUTION REACTION;

EID: 2542466767     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.04.058     Document Type: Article

References (23)

1. Brown D.J. Taylor E.C., Weissberger A. The Pyrimidines. 1994;Wiley, New York
2. Katrizky A., Rees C.W. Comprehensive Heterocyclic Chemistry. Vol. 3:1984;Pergamon, Oxford. p 111
3. Nakayama, T.; Takashi, H. Jpn Kokai. Tokkyo Koho JP 03167178 A2, 1991; Chem. Abstr. 1991, 115, 256204.
4. Sasaki K., Arimoto Y., Ohtomo H., Nakaya T., Takashi H. J. Heterocycl. Chem. 30:1993;993
5. Sasaki K., Arimoto Y., Ohtomo H., Nakayama T., Takashi H. J. Heterocycl. Chem. 30:1993;989
6. Sasaki K., Hirota T., Arimoto Y., Satoh Y., Ohtomo H., Nakayama T. J. Heterocycl. Chem. 27:1990;1771
7. Troschuetz R. Arch. Pharm. 321:1988;765-766
8. Robl, J. A.; Bang-Chi, C.; Chong-Qing, S. US Patent US 20002061901; Chem. Abstr., 2001, 136, 401651.
9. Ganguly A.K., Doll A.K., Girijavallabhan V.M. Curr. Med. Chem. 8:2001;1419
10. Herrera A., Martínez-Álvarez R., Chioua R., Chioua M. Tetrahedron Lett. 2003;2149
11. Garcia Martinez A., Herrera Fernandez A., Moreno Jimenez F., Garcia Fraile A., Subramanian L.R., Hanack M. J. Org. Chem. 57:1992;1627
12. Baraznekok L., Nenajdenko V.G., Balenkova E. Tetrahedron. 56:2000;3077
13. Corbin P.S., Zimmerman S.C., Thiessen P.A., Hawryluk N.A., Murray T.J. J. Am. Chem. Soc. 123:2001;10475
14. Ma Y., Kolotuchin S.V., Zimmerman S.C. J. Am. Chem. Soc. 124:2002;13757
15. Marczak R., Hoang V.T., Noworyta K., Zandler M.E., Kutmer W., D'Souza F. J. Chem. Mater. 12:2002;2123
16. Herrera A., Martínez-Alvarez R., Ramiro P., Chioua R., Chioua M. Synthesis. 2004;503
17. García Martinez A., Herrera Fernández A., Martínez-Álvarez R., Teso Vilar E., García Fraile A., Osío Barcina J., Pargada Iglesias L. Tetrahedron Lett. 1987;1929
18. García Martínez A., Herrera Fernández A., Martínez-Álvarez R., Teso Vilar E., García Fraile A., Osío Barcina J., Pargada Iglesias L., Unanue R., Subramanian L.R., Hanack M. J. Heterocycl. Chem. 25:1988;1237
19. Ritter J.J., Minieri P.P. J. Am. Chem. Soc. 70:1948;4045
20. Stang P.J., Hanack M., Subramanian L.R. Synthesis. 1982;85
21. Cacchi S., Lupi A. Tetrahedron Lett. 1992;3939
22. Kwon H.B., McKee B.H., Stille J.K. J. Org. Chem. 55:1990;3114
23. Hanack M., Subramanian L.R. Houben-Weyl, Methoden der Organischen Chemie, Carbokationen, Carbokationen-Radikale. E19c:1990;Georg Thieme, Stuttgart. p 98