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Volumn 346, Issue 5, 2004, Pages 573-578

Polymer-supported indium lewis acid: Highly versatile catalyst for regio- and stereoselective ring-opening of epoxides

Author keywords

Asymmetric catalysis; Heterogeneous catalysis; Immobilization; Indium; Ring opening

Indexed keywords

CARBON; EPOXIDE; INDIUM; LEWIS ACID; POLYMER; SULFUR;

EID: 2542454583     PISSN: 16154150     EISSN: None     Source Type: Journal    
DOI: 10.1002/adsc.200303236     Document Type: Article
Times cited : (53)

References (38)
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    • EP was calculated as: (In content x 3)/proton exchange capacity (≅ 4.7 mmol/g).
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    • note
    • 2O, rt, 24 h) was carried out. Under these optimal conditions the desired β-indolyl alcohol 3aa was isolated only in traces, 1,1-bisindolyl-2-phenylethane being the major reaction product (yield: 85%), derived from the double addition of 2a to phenylacetaldehyde (rearrangement of 1a).
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    • 1st cycle: yield = 53%, ee = 98%; 2nd cycle: yield = 67%, ee = 98%; 3rd cycle: yield = 57%, ee = 98%; 4th cycle: yield = 52%, ee = 96%; 5th cycle: yield = 56%, ee = 96%.
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