Thrombospondin-1 up-regulates tumor cell invasion through the urokinase plasminogen activator receptor in head and neck cancer cells

Journal of Surgical Research

Volumn 120, Issue 1, 2004, Pages 21-26

  Albo, D ^a   Tuszynski, G P ^b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b Temple University   (United States)

Author keywords

head and neck; plasmin; squamous cell carcinoma; thrombospondin 1; TSP 1; tumor cell invasion; uPAR; urokinase plasminogen activator receptor

Indexed keywords

AMINOCAPROIC ACID; COLLAGEN; GLYCOSYLPHOSPHATIDYLINOSITOL; LIGAND; NEUTRALIZING ANTIBODY; PHOSPHOLIPASE C; PLASMINOGEN; THROMBOSPONDIN 1; UROKINASE RECEPTOR;

ADENOCARCINOMA; ARTICLE; BINDING AFFINITY; CANCER CELL; CELL INVASION; CELL STRAIN KB; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SPECIFICITY; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; SQUAMOUS CELL CARCINOMA; TUMOR CELL; UPREGULATION;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; HEAD AND NECK NEOPLASMS; HUMANS; NEOPLASM INVASIVENESS; RECEPTORS, CELL SURFACE; THROMBOSPONDIN 1; UP-REGULATION;

EID: 2542436741     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jss.2004.03.007     Document Type: Article

References (51)

1. Mignatti P., Rifkin D.B. Biology and biochemistry of proteinases in tumor cell invasion. Physiol. Rev. 73:1993;161
2. Blasi F. Molecular mechanisms of protease-mediated tumor invasiveness. J. Surg. Oncol. 3:(Suppl.):1993;21
3. Testa J.E., Quigley J.P. The role of urokinase-type plasminogen activator in aggressive tumor cell behavior. Cancer Metast. Rev. 9:1990;353
4. Plow E., Freaney D.E., Plescia J., Miles L.A. The plasminogen system and cell surfaces Evidence for plasminogen and urokinase receptors on the same cell type. J. Cell. Biol. 103:1986;2411
5. Vassalli J., Sappino A.P., Belin D. The plasminogen activator/plasmin system. J. Clin. Invest. 88:1991;1067
6. Mignatti P., Rifkin D. Biology and biochemistry of proteinases in tumor invasion. Physiol. Rev. 73:1993;161
7. Vassalli J., Baccino D., Belin D. A cellular binding site for the Mr 55, 000 form of the human plasminogen activator, urokinase. J. Cell. Biol. 100:1985;86
8. Roldan A., Cubellis M.V., Masucci N., Behrendt L.R., Lund K., Dano E., Appela E., Blasi F. Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J. 9:1990;467
9. Blasi F., Behrendt N., Cubellis M.V., Ellis V., Lund L.R., Masucci M.T. The urokinase receptor and regulation of cell surface plasminogen activation. Cell. Diff. Dev. 32:1990;247
10. Ploug M., Kjalke M., Ronne E., et al. Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins. J. Biol. Chem. 268:1993;17539
11. Ossowski L., Clunie G., Masucci M.T., Blasi F. In vivo paracrine interaction between urokinase and its receptor Effect on tumor cell invasion. J. Cell Biol. 115:1991;1107
12. Ossowski L. Invasion of connective tissue by human carcinoma cell lines Requirement for urokinase, urokinase receptor, and interstitial collagenase. Cancer Res. 52:1992;6754
13. Yu W., Kim J., Ossowski L. Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy. J. Cell Biol. 137:1997;767
14. Kook Y.H., Adamski J., Zelent A., Ossowski L. The effect of antisense inhibition of urokinase receptor in human squamous cell carcinoma on malignancy. EMBO J. 13:1994;3983
15. Mohanam S., Sawaya R., McCutcheon I., et al. Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody. Cancer Res. 53:1993;4143
16. Mohanam S., Sawaya R.E., Yamamoto M., et al. Proteolysis and invasiveness of brain tumors Role of urokinase-type plasminogen activator receptor. J. Neurooncol. 22:1994;153
17. Kariko K., Kuo A., Boyd D., et al. Overexpression of urokinase receptor increases matrix invasion without altering cell migration in a human osteosarcoma cell line. Cancer Res. 53:1993;3109
18. Costantini V., Sidoni A., Deveglia R., et al. Combined overexpression of urokinase, urokinase receptor, and plasminogen activator inhibitor-1 is associated with breast cancer progression An immunohistochemical comparison of normal, benign, and malignant breast tissues. Cancer. 77:1996;1079
19. Graeff H., Harbeck N., Pache L., Wilhelm O., Janicke F., Schmitt M. Prognostic impact and clinical relevance of tumor associated proteases in breast cancer. Fibrinolysis. 6:1992;45
20. Foekens J., Schmitt M., Van Putten W.L., Peters H.A., Kramer M.D., Janicke F. Prognostic value of urokinase-type plasminogen activator in 671 primary breast cancer patients. Cancer Res. 1992:1992;6101
21. Tuszynski G.P., Nicosia R.F. Localization of thrombospondin and its cysteine-serine-valine-threonine-cysteine-glycine-specific receptor in human breast carcinoma. Lab. Invest. 70:1994;228
22. Clezardin P., Frappart L., Clerget M., et al. Expression of thrombospondin (TSP1) and its receptors (CD36 and CD51) in normal, hyperplastic, and neoplastic human breast. Cancer Res. 53:1993;1421
23. Tuszynski G.P. The role of thrombospondin in malignancy and tumor cell metastasis. Lahav J. Thrombospondin. 1993;209-225 CRC Press, Boca Raton, FL
24. Tuszynski G.P., Gasic T.B., Rothman V.L., et al. Thrombospondin, a potentiator of tumor cell metastasis. Cancer Res. 47:1987;4130
25. Yabkowitz R., Mansfield P.J., Dixit V.M., Suchard S.J. Motility of human carcinoma cells in response to thrombospondin Relationship to metastatic potential and thrombospondin structural domains. Cancer Res. 53:1993;378
26. Albo D., Arnoletti J.P., Castiglioni A., et al. Thrombospondin (TSP) and transforming growth factor beta 1 (TGF-beta) promote human A549 lung carcinoma cell plasminogen activator inhibitor type 1 (PAI-1) production and stimulate tumor cell attachment in vitro. Biochem. Biophys. Res. Commun. 203:1994;857
27. Arnoletti J., Albo D., Granick M.S., Solomon M.P., Castiglioni A., Rothman V.L., Tuszynski G.P. Thrombospondin and transforming growth factor-beta 1 increase expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in human MDA-MB-231 breast cancer cells. Cancer. 76:1995;998
28. Albo D., Berger D.H., Wang T.N., et al. Thrombospondin-1 and transforming growth factor-beta l promote breast tumor cell invasion through up-regulation of the plasminogen/plasmin system. Surgery. 122:1997;493. discussion 499
29. Albo D., Berger D.H., Tuszynski G.P. The effect of thrombospondin-1 and TGF-beta 1 on pancreatic cancer cell invasion. J. Surg. Res. 76:1998;86
30. Wang T.N., Qian X., Granick M.S., et al. Thrombospondin-1 (TSP-1) promotes the invasive properties of human breast cancer. J. Surg. Res. 63:1996;39
31. Wang T.N., Qian X.H., Granick M.S., et al. Inhibition of breast cancer progression by an antibody to a thrombospondin-1 receptor. Surgery. 120:1996;449
32. Arnoletti J.P., Albo D., Jhala N., et al. Computer-assisted image analysis of tumor sections for a new thrombospondin receptor. Am. J. Surg. 168:1994;433
33. Tuszynski G.P., Srivastava S., Switalska H.I., et al. The interaction of human platelet thrombospondin with fibrinogen. J. Biol. Chem. 260:1985;12240
34. Schultz-Cherry S., Ribeiro S., Gentry L., Murphy-Ullrich J.E. Thrombospondin binds and activates the small and large forms of latent transforming growth factor-b in a chemically defined system. J. Biol. Chem. 269:1994;26775
35. Keski-Oja J., Koli K., Lohi L., Laiho M. Growth factors in the regulation of the plasminogen plasmin-system in tumor cells. Semin. Thromb. Hemost. 17:1991;231
36. Laiho M., Keski-Oja J. Growth factors in the regulation of pericellular proteolysis. Cancer Res. 49:1989;2533
37. Schultz-Cherry S., Chen H., Mosher D.F., et al. Regulation of transforming growth factor-b activation by discrete sequences of thrombospondin 1. J. Biol. Chem. 270:1995;7304
38. Schultz-Cherry S., Lawler J., Murphy-Ullrich J.E. The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-b. J. Biol. Chem. 269:1994;26783
39. Schultz-Cherry S., Murphy-Ullrich J.E. Thrombospondin causes activation of latent transforming growth factor-b secreted by endothelial cells by a novel mechanism. J. Cell Biol. 122:1993;923
40. Albo D., Rothman V.L., Roberts D.D., Tuszynski G.P. Tumour cell thrombospondin-1 regulates tumour cell adhesion and invasion through the urokinase plasminogen activator receptor. Br. J. Cancer. 83:2000;298
41. Albo D., Berger D.H., Rothman V.L., Tuszynski G.P. Role of urokinase plasminogen activator receptor in thrombospondin 1-mediated tumor cell invasion. J. Surg. Res. 82:1999;331
42. Weinstat-Saslow D.L., Zabrenetzky V.S., VanHoutte K., et al. Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. Cancer Res. 54:1994;6504
43. Varani J., Riser B.L., Hughes L.A., et al. Characterization of thrombospondin synthesis, secretion and cell surface expression by human tumor cells. Clin. Exp. Metastasis. 7:1989;265
44. Castle V., Varani J., Fligiel S., et al. Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma. J. Clin. Invest. 87:1991;1883
45. Bornstein P. Diversity of function is inherent in matricellular proteins An appraisal of thrombospondin 1. J. Cell Biol. 130:1995;503
46. r 80, 000/105, 000 receptor. Cancer Res. 51:1991;3648
47. Roth J.J., Reiver D.M., Granick M.S., et al. Histopathology and clinical assessment correlate with the cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) receptor of thrombospondin-1 in breast tumors. Histol. Histopathol. 12:1997;1013
48. Tuszynski G.P., Rothman V.L., Deutch A.H., et al. Biological activities of peptides and peptide analogues derived from common sequences present in thrombospondin, properdin, and malarial proteins. J. Cell Biol. 116:1992;209
49. Tuszynski G.P., Rothman V.L., Papale M., et al. Identification and characterization of a tumor cell receptor for CSVTCG, a thrombospondin adhesive domain. J. Cell Biol. 120:1993;513
50. Tuszynski G.P., Nicosia R.F. The role of thrombospondin-1 in tumor progression and angiogenesis. Bioessays. 18:1996;71
51. Wakiyama T., Shinohara T., Shirakusa T., et al. The localization of thrombospondin-1 (TSP-1), cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) TSP receptor, and matrix metalloproteinase-9 (MMP-9) in colorectal cancer. Histol. Histopathol. 16:2001;345