Specific molecular alterations in the norpA-encoded phospholipase C of Drosophila and their effects on electrophysiological responses in vivo

Journal of Neurochemistry

Volumn 89, Issue 4, 2004, Pages 998-1008

  Yoon, Jaeseung ^b   Leung, Hung Tat ^a   Lee, Seunghee ^b,c   Geng, Chaoxian ^a,d   Kim, Younkyung ^b   Baek, Kwanghee ^b   Pak, William L ^a  

^a PURDUE UNIVERSITY   (United States)

^b Kyung Hee University   (South Korea)

^c PanGen Biotech Inc   (South Korea)

^d Cambria Pharmaceuticals Inc   (United States)

Author keywords

Drosophila mutants; Functional domains; GTPase activating protein; Phospholipase C; Phototransduction; Structure function analysis

Indexed keywords

AMINO ACID; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MUTANT PROTEIN; PHOSPHOLIPASE C; DROSOPHILA PROTEIN; NORPA PROTEIN, DROSOPHILA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; ELECTRORETINOGRAPHY; ENZYME ACTIVITY; LATENT PERIOD; NONHUMAN; PHOTOSENSITIVITY; PHOTOTRANSDUCTION; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; ANIMAL; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHOTORECEPTOR; PHYSIOLOGY; REACTION TIME; SEQUENCE HOMOLOGY;

ANIMALIA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ELECTROPHYSIOLOGY; ELECTRORETINOGRAPHY; ENZYME ACTIVATION; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHOLIPASE C; PHOTORECEPTORS, INVERTEBRATE; REACTION TIME; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 2542431394     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02384.x     Document Type: Article

References (37)

1. Bairoch A. and Cox J. A. (1990) EF-hand motifs in inositol phospholipid-specific phospholipase C. FEBS Lett. 269, 454-456.
2. Berridge M. J. (1993) Inositol trisphosphate and calcium signaling. Nature 361, 315-325.
3. q/II, its physiologic regulator. Cell 70, 411-418.
4. Bloomquist B. T., Shortridge R. D., Schneuwly S., Perdew M., Montell C., Steller H., Rubin G. and Pak W. L. (1988) Isolation of a putative phospholipase C gene of Drosophila, norpA, and its role in phototransduction. Cell 54, 723-733.
5. Cheng H. F., Jiang M. J., Chen C. L., Liu S. M., Wong L. P., Lomasney J. W. and King K. (1995) Cloning and identification of amino acid residues of human phospholipase Cδ1 essential for catalysis. J. Biol. Chem. 270, 5495-5505.
6. Cook B., Bar-Yaacov M., Cohen Ben-Ami H.; Goldstein R. E., Paroush Z., Selinger Z. and Minke B. (2000) Phospholipase C and termination of G-protein-mediated signaling in vivo. Nat. Cell Biol. 2, 296-301.
7. Ellis M. V., Katan S.U. and Katan M. (1995) Mutations within a highly conserved sequence present in the X region of phosphoinositide-specific phospholipase C-δ1. Biochem. J. 307, 69-75.
8. Essen L. O., Perisic O., Cheung R., Katan M. and Williams R. L. (1996) Crystal structure of a mammalian phosphoinositide-specific phospholipase Cδ. Nature 380, 595-602.
9. Ferguson K. M., Lemmon M. A., Schlessinger J. and Sigler P. B. (1995) Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain. Cell 83, 1037-1046.
10. 2+ channel in Drosophila photoreceptors. Neuron 8, 643-651.
11. 2+-channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC, and InaD. EMBO J. 15, 7036-7045.
12. van Huizen R., Miller K., Chen D. M., Li Y., Lai Z. C., Raab R. W., Stark W. S., Shortridge R. D. and Li M. (1998) Two distantly positioned PDZ. domains mediate multivalent INAD-phospholipase C interactions essential for G protein-couple signaling. EMBO J. 17, 2285-2297.
13. Larrivee D. C., Conrad S. K., Stephenson R. S. and Pak W. L. (1981) Mutation that selectively affects rhodopsin concentration in the peripheral photoreceptors of Drosophila melanogaster. J. Gen. Physiol. 78, 521-545.
14. Minke B. and Hardie R. C. (2000) Genetic dissection of Drosophila phototransduction, In: Handbook of Biology Physics (Stavenga, D. G., DeGrip, W. J. and Pugh, E. N. Jr, eds), Vol. 3, pp. 449-525. Elsevier Science B.V., Amsterdam.
15. Montell C. (1999) Visual transduction in Drosophila. Annu. Rev. Cell. Dev. Biol. 15, 231-268.
16. Naka K. I. and Rushton W. A. (1968) S-potential and dark adaptation in fish. J. Physiol. 194, 259-269.
17. Niemeyer B. A., Suzuki E., Scott K., Jalink K. and Zuker C. S. (1996) The Drosophila light-activated conductance is composed of the two channels TRP and TRPL. Cell 85, 651-659.
18. Pak W. L. and Leung H. T. (2003) Genetic approaches to visual transduction in Drosophila melanogaster. Receptor Channels 9, 149-167.
19. Pak W. L., Ostroy S. E., Deland M. C. and Wu C. F. (1976) Photoreceptor mutant of Drosophila: is protein involved in intermediate steps of phototransduction? Science 194, 956-959.
20. Paulssen R. H., Woodson J., Liu Z. and Ross E. M. (1996) Carboxyl-terminal fragments of phospholipase C-β1 with intrinsic Gq GTPase-activating protein (GAP) activity. J. Biol. Chem. 271, 26622-26629.
21. Pearn M. T., Randall L. L., Shortridge R. D., Burg M. G. and Pak W. L. (1996) Molecular, biochemical, and electrophysiological characterization of Drosophila norpA mutants. J. Biol. Chem. 271, 4937-4945.
22. Prasanna Murthy S. N., Lomasney J. W., Mak E. C. and Lorand L. (1999) Interactions of G(h)/transglutaminase with phospholipase Cdelta1 and with GTP. Proc. Natl Acad. Sci. USA 96, 11815-11819.
23. Rameh L. E., Rhee S. G., Spokes K., Kazlauskas A., Cantley L. C. and Cantley L. G. (1998) Phosphoinositide 3-kinase regulates phospholipase Cgamma-mediated calcium signaling. J. Biol. Chem. 273, 23750-23757.
24. Reuss H., Mojet M. H., Chyb S. and Hardie R. C. (1997) In vivo analysis of the Drosophila light-sensitive channels, TRP and TRPL. Neuron 19, 1249-1259.
25. Rhee S. G., Suh P. G., Ryu S. H. and Lee S. Y. (1989) Studies of inositol phospholipid-specific phospholipase C. Science 244, 546-550.
26. Ross E. M., Berstein G. and Karandikar M. (1994) Endothelium-Derived Factors and Vascular Functions. (Masaki, T., ed.), pp. 211-218. Elsevier. Science Publishers, B.V., Amsterdam.
27. Sanger F., Nicklen S. and Coulson A. R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA 74, 5463-5467.
28. Saraste M. and Hyvönen M. (1995) Pleckstrin homology domains: a fact file. Curr. Opin. Struct. Biol. 5, 403-408.
29. Scott K., Sun Y., Beckingham K. and Zuker C. S. (1997) Calmodulin regulation of Drosophila light-activated channels and receptor function mediates termination of the light response in vivo. Cell 91, 375-383.
30. Shieh B. H., Zhu M. Y., Lee J. K., Kelly I. M. and Bahiraei F. (1997) Association of INAD with NORPA is essential for controlled activation and deactivation of Drosophila phototransduction in vivo. Proc. Natl Acad. Sci. USA 94, 12682-12687.
31. Simões A. P., Camps M., Schnabel P. and Gierschik P. (1995) Mutational analysis of a putative phosphoinositide binding site in phospholipase C-beta 2. FEBS Lett. 365, 155-158.
32. Singer W. D., Brown H. A. and Sternweis P. C. (1997) Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D. Annu. Rev. Biochem. 66, 475-509.
33. Tsunoda S., Sierralta J., Sun Y., Bodner R., Suzuki E., Becker A., Socolich M. and Zuker C. S. (1997) A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade. Nature 388, 243-249.
34. Wahl M. I., Jones G. A., Nishibe S., Rhee S. G. and Carpenter G. (1992) Growth factor stimulation of phospholipase C-gamma 1 activity: comparative properties of control and activated enzymes. J. Biol. Chem. 267, 10447-10456.
35. Wang T., Pentyala S., Elliot J. T., Dowal L., Gupta E., Rebecchi M. J. and Scarlata S. (1999) Selective interaction of the C2 domains of phospholipase C-beta1 and -beta2 with activated Gαq subunits: an alternative function for C2-signaling modules. Proc. Natl Acad. Sci. USA 96, 7843-7846.
36. Williams R. L. and Katan M. (1996) Structural views of phosphoinositide-specific phospholipase C: signalling the way ahead. Structure 4, 1387-1394.
37. Zhu L., McKay R. R. and Shortridge R. D. (1993) Tissue-specific expression of phospholipase C encoded by the norpA gene of Drosophila melanogaster. J. Biol. Chem. 268, 15994-16001.