Acute ischemic cardiac dysfunction is attenuated via gene transfer of a peptide inhibitor of the β-adrenergic receptor kinase (βARK1)

Journal of Gene Medicine

Volumn 7, Issue 9, 2005, Pages 1172-1177

  Tevaearai, Hendrik T ^a   Walton, G Brant ^b   Keys, Janelle R ^b   Koch, Walter J ^c   Eckhart, Andrea D ^c  

^a PSI   (Switzerland)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

adrenergic receptor; adrenergic receptor kinase; Gene therapy; Myocardial ischemia; Off pump coronary artery bypass graft

Indexed keywords

ADENOVIRUS VECTOR; ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR KINASE INHIBITOR; BUFFER; PHOSPHATE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; ENZYME ACTIVITY; GENE TRANSFER; HEART HEMODYNAMICS; HEART INFARCTION SIZE; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE RELAXATION; HEART MUSCLE ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RECEPTOR DENSITY; SUTURE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS PARTICLE;

ADENOVIRIDAE; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; CORONARY ARTERY BYPASS, OFF-PUMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; GENE THERAPY; GENETIC VECTORS; HEART VENTRICLES; MYOCARDIAL ISCHEMIA; PEPTIDES; POSTOPERATIVE COMPLICATIONS; PREMEDICATION; RABBITS; RECEPTORS, ADRENERGIC, BETA; RECOMBINANT PROTEINS; TRANSGENES; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

ORYCTOLAGUS CUNICULUS;

EID: 25144521715     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.770     Document Type: Article

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