Generic method for systematic phase selection and method development of biochromatographic processes: Part I. Selection of a suitable cation-exchanger for the purification of a pharmaceutical protein

Journal of Chromatography A

Volumn 1092, Issue 1-2, 2005, Pages 89-100

  Lohrmann, Martin ^a,c   Schulte, Michael ^b   Strube, Jochen ^c  

^a TU DORTMUND UNIVERSITY   (Germany)

^b MERCK KGAA   (Germany)

^c BAYER AG   (Germany)

Author keywords

Biochromatography; Ion exchange chromatography; Pharmaceutical protein; Phase screening; Phase selection; Preparative chromatography

Indexed keywords

ADSORBENTS; CHROMATOGRAPHIC ANALYSIS; DRUG THERAPY; HYDROPHOBICITY; ION EXCHANGE; POSITIVE IONS; SEPARATION; SYNTHESIS (CHEMICAL);

ION-EXCHANGE CHROMATOGRAPHY; PHARMACEUTICAL PROTEIN; PHASE SCREENING; PHASE SELECTION; PREPARATIVE CHROMATOGRAPHY;

PROTEINS;

ADSORBENT;

ADSORPTION; ANALYTIC METHOD; CATION EXCHANGE; CHEMICAL PROCEDURES; CHROMATOGRAPHY; CONFERENCE PAPER; HYDROPHOBICITY; MOLECULAR SIZE; MOLECULAR WEIGHT; PHASE TRANSITION; PRESSURE; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN TARGETING; SEPARATION TECHNIQUE; SIGNAL TRANSDUCTION;

CATION EXCHANGE RESINS; CHROMATOGRAPHY, ION EXCHANGE; PHARMACEUTICAL PREPARATIONS; PRESSURE; PROTEINS;

EID: 25144498993     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2005.05.067     Document Type: Conference Paper

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