Inhalation devices

CMAJ. Canadian Medical Association Journal

Volumn 173, Issue 6 SUPPL., 2005, Pages

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; FENOTEROL; FLUORINATED HYDROCARBON; FLUTICASONE; FORMOTEROL; PROPELLANT; TIOTROPIUM BROMIDE;

ASTHMA; COGNITION; CONFERENCE PAPER; DRY POWDER; FACE MASK; HUMAN; INHALER; MAINTENANCE THERAPY; METERED DOSE INHALER; NEBULIZER; PATIENT CARE; PATIENT EDUCATION;

EID: 25144488288     PISSN: 08203946     EISSN: 14882329     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (81)

1. Busse WW, Brazinsky S, Jacobson K, Stricker W, Schmitt K, Vanden Burgt J, et al. Efficacy response of inhaled beclomethasone dipropionate in asthma is proportional to dose and is improved by formulation with a new propellant. J Allergy Clin Immunol 1999;104(6):1215-22.
2. Farmer IS, Middle M, Savic J, Perri VL, Herdman MJ. Therapeutic equivalence of inhaled beclomethasone diproprionate with CFC and non-CFC (HFA 134a) propellants both delivered via the Easibreathe inhaler for the treatment of paediatric asthma. Respir Med 2000;94(1):57-63.
3. Leach CL, Davidson PJ, Hasselquist BE, Boudreau RJ. Lung depostion of hydrofluoroalkane-134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chloroflourocarbon beclomethasone. Chest 2002;122(2):510-6.
4. Leach CL, Davidson PJ, Bredow TS, Boudreau RJ. Patient factors influencing the deposition of HFA-beclomethasone dipropionate metered dose inhaler. Eur Respir J 1998;12:66s.
5. Bleecker ER, Tinkelman DG, Ramsdell J, Ekholm BP, Klinger NM, Colice GL, et al. Proventil HFA provides bronchodilation comparable to ventolin over 12 weeks of regular use in asthmatics. Chest 1998;113(2):283-9.
6. Dolovich M, Leach C. Drug delivery devices and propellants. In: Busse W, Holgate S, editors. Asthma and rhinitis. 2nd ed. London: Blackwell Science; 2000. p. 1719-31.
7. Hirst PH, Pitcairn GR, Richards JC, Rohatagi S, Gillen MS, Newman SP. Deposition and pharmacokinetics of an HFA formulation of triamcinolone acetonide delivered by pressurized metered dose inhaler. J Aerosol Med 2001;14(2):155-65.
8. Richards J, Hirst P, Pitcairn G, Mahashabde S, Abramowitz W, Nolting A, et al. Deposition and pharmacokinetics of flunisolide delivered from pressurized inhalers containing non-CFC and CFC propellants. J Aerosol Med 2001;14(2):197-208.
9. Pedersen S, Warner J, Wahn U, Staab D, Le Bourgeois M, Van Essen-Zandvliet E, et al. Growth, systemic safety, and efficacy during 1 year of asthma treatment with different beclomethasone diproprionate formulations: an open-label, randomized comparison of extrafine and conventional aerosols in children. Pediatrics 2002;109(6):e92.
10. Zanen P, Go LT, Lammers JW. Optimal particle size for beta 2 agonist and anticholinergic aerosols in patients with severe airflow obstruction. Thorax 1996;51(10):977-80.
11. Kleerup EC, Tashkin DP, Cline AC, Ekholm BP. Commutative does-response study of non-CFC propellant HFA 134a salbutamol sulfate metered-dose inhaler in patients with asthma. Chest 1996;109(3):702-7.
12. Ramsdell JW, Colice GL, Ekholm BP, Klinger NM. Cumulative dose response study comparing HFA-134a albuterol sulfate and conventional CFC albuterol in patients with asthma. Ann Allergy Asthma Immunol 1998;81(6):593-9.
13. Dockhorn R, Vanden Burgt JA, Ekholm BP, Donnell D, Cullen MT. Clinical equivalence of a novel non-chloroflourocarbon-containing salbutamol sulfate metered-dose inhaler and a conventional chloroflourocarbon inhaler in patients with asthma. J Allergy Clin Immunol 1995;96(1):50-6.
14. Mitchell JP, Nagel MW. In vitro performance testing of three small volume-holding chambers under conditions that correspond with use by infants and small children. J Aerosol Med 1997;10(4):341-9.
15. Sennhauser FH, Sly PD. Pressure flow characteristics of the valve in spacer devices. Arch Dis Child 1989;64(9):1305-7.
16. Bisgaard H. Future options for aerosol delivery to children. Allergy 1999;54 Suppl 49:97-103.
17. Finlay WH, Zuberbuhler P. In vitro comparison of beclomethasone and salbutamol metered-dose inhaler aerosols inhaled during pediatric tidal breathing from four valved holding chambers. Chest 1998;114(6):1676-80.
18. Dubus JC, Rhem R, Dolovich M. Delivery of HFA and CFC salbutamol from spacer devices used in infancy. Int J Pharm 2001;222(1):101-8.
19. Bisgaard H, Anhoj J, Klug B, Berg E. A non-electrostatic spacer for aerosol delivery. Arch Dis Child 1995;73(3):226-30.
20. Janssens HM, Devadason SG, Hop WC, LeSoeuf PN, De Jongste JC, Tiddens HA. Variability of aerosol delivery via spacer devices in young asthmatic children in daily life. Eur Respir J 1999;13(4):787-91.
21. Bisgaard H. A metal aerosol holding chamber devised for young children with asthma. Eur Respir J 1995;8(5):856-60.
22. Pierart F, Wildhaber JH, Vrancken I, Devadason SG, Le Souef PN. Washing plastic spacers in household detergent reduces electrostatic charge and greatly improves delivery. Eur Respir J 1999;13(3):673-8.
23. Clark DJ, Lipworth BJ. Effect of multiple actuations, delayed inhalation and antistatic treatment on the lung bioavailability of salbutamol via spacer device. Thorax 1996;51(10):981-4.
24. Barry PW, O'Callaghan C. The effect of delay, multiple actuations and spacer static charge on the in vitro delivery of budesonide from the Nebuhaler. Br J Clin Pharmacol 1995;40(1):76-8.
25. Pedersen JZ, Bundgaard A. Comparative efficacy of different methods of nebulizing terbutaline. Eur J Clin Pharmacol 1983;25(6):739-42.
26. Madsen EB, Bundgaard A, Hidinger KG. Cumulative does-response study comparing terbutaline pressurized aerosol administered via a pearshaped spacer and terbutaline in a nebulized solution. Eur J Clin Pharmacol 1982; 23(1):27-30.
27. Rubin BK, Nakanishi AK, Lamb BM, Kabance E, Johnston P, Hawkins J. Dose equivalence of salbutamol given by metered dose aerosol with AeroChamber or by wet nebulization in children with stable asthma. Eur Respir J 1993;6(suppl. 17):353S.
28. Gappa M, Gartner M, Poets CF, von der Hardt H. Effects of salbutamol delivery from a metered dose inhaler versus jet nebulizer on dynamic lung mechanics in very preterm infants with chronic lung disease. Pediatr Pulmonol 1997;23:442-8.
29. Salmon B, Wilson NM, Silverman M. How much aerosol reaches the lungs of wheezy infants and toddlers? Arch Dis Child 1990;65(4):401-3.
30. Laberge S, Spier S, Drblik SP, Turgeon JP. Comparison of inhaled terbutaline administered by either Turbuhaler dry powder inhaler to metered-dose inhaler with spacer in preschool children with asthma. J Pediatr 1994;124(5 pt 1):815-7.
31. Drblik S, Lapierre G, Thivierge R, Turgeon J, Gaudreault P, Cummins-McMannus B, et al. Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurized metered dose inhale with Nebuhaler spacer in children during an acute asthma episode. Arch Dis Child 2003;88(4):319-23.
32. Thorsson L, Edsbacker S, Conradson TB. Lung deposition of budesonide from Turbuhaler is twice that from a pressurized metered-dose inhaler P-MDI. Eur Respir J 1994;7(10):1839-44.
33. Agertoft L, Pedersen S. Importance of the inhalation device on the effect of budesonide. Arch Dis Child 1993;69(1):130-3.
34. Mellen A, Arvidsson P, Palmqvist M, Lotvall J. Equivalent bronchodilation with salbutamol given via pMDI or turbuhaler. Am J Respir Crit Care Med 1999;159(5 pt 1):1663-5.
35. Borgstrom L, Derom E, Stahl E, Wahlin-Boll E, Pauwels R. The inhalation device influences lung deposition and bronchodilation effect of terbutaline. Am J Respir Crit Care Med 1996;153(5):1636-40.
36. Lundback B, Alexander M, Day J, Herbert J, Holzer R, Van Uffelen R, et al. Evaluation of fluticasone propionate (500 micrograms/day) administered either as dry powder via a Diskhaler inhaler or pressurized inhaler and compared with beclomethasone dipropionate (1000 microgram/day) administered by pressurized inhaler. Respir Med 1993;87(8):609-20.
37. Bisgaard H, Klug B, Sumby BS, Burnell PK. Fine particle mass from the Diskus inhaler and Turbuhaler inhaler in children with asthma. Eur Respir J 1998;11(5):1111-5.
38. Ahrens R, Lux C, Bahl T, Han SH. Choosing the metered-dose inhaler spacer or holding chamber that matches the patient's need: evidence that the specific drug being delivered is an important consideration. J Allergy Clin Immunol 1995;96(2):288-94.
39. Barry PW, O'Callaghan C. Inhalational drug delivery from seven different spacer devices. Thorax 1996;51:835-40.
40. Everard ML, Devadason SG, Le Souef PN. Particle size selection device for use with Turbohaler. Thorax 1996;51(5):537-9.
41. Agertoft L, Pedersen S. Importance of training for correct Turbuhaler use in preschool children. Acta Paediatr 1998;87(7):842-7.
42. Gleeson JG, Price JF. Nebuhaler technique. Br J Dis Chest 1988;82(2):172-4.
43. James RW, Masters IB. Single breath versus panting technique in salbutamol delivery through a 750 mL spacing device. Pediatr Pulmonol 1990;8(4):263-7.
44. Pedersen S, Hansen OR, Fuglsang G. Influence of inspiratory flow rate upon the effect of the turbuhaler. Arch Dis Child 1990;65(3):308-10.
45. Hansen OR, Pedersen S. Optimal inhalation technique with terbutaline Turbuhaler. Eur Respir J 1989;2(7):637-9.
46. Lenney J, Innes JA, Crompton GK. Inappropriate inhaler use: assessment of use and patient preference of seven inhalation devices. Respir Med 2000; 94(5):496-500.
47. Hilton S. An audit of inhaler technique among asthma patients of 34 general practitioners. Br J Gen Pract 1990;40:505-6.
48. Chen SH, Yin, Huang JL. An exploration of the skills needed for inhalation therapy in schoolchildren with asthma in Taiwan. Ann Allergy Asthma Immunol 2002;9:311-5.
49. Cochrane MG, Bala MV, Downs KE, Mauskopf J, Ben-Joseph RH. Inhaled corticosteroids for asthma therapy. Chest 2000;117:542-50.
50. Kamps AW, Brand PL, Roorda RJ. Determinants of correct inhalational technique in children attending a hospital-based asthma clinic. Acta Paediatr 2002;91:159-63.
51. Giraud V, Roche N. Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability. Eur Respir J 2002;19:246-51.
52. Kamps AW, van Ewijk B, Roorda RJ, Brand PL. Por inhalation technique even after inhalation instructions, in children. Pediatr Pulmonol 2000;29:39-42.
53. Vodoff MV, Gilbert B, De Lumley L, Dutau G. Method for using inhalational chambers with facial masks in asthma. Evaluation in 60 children below 4 years of age. Arch Pediatr 2001;8:598-603.
54. Van der Palen J, Klein JJ, Van Herwaarden CL, Zielhuis GA, Seydel ER. Multiple inhalers confuse asthma patients. Eur Respir J 1999;14:1034-7.
55. Brocklebank D, Ram F, Wright J, Barry P, Cates C, Davies L, et al. Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature. Health Technol Assess 2001;5:1-149.
56. Dolovich MB, Ahrens RC, Hess DR, Anderson P, Dhand R, Rau JL, et al. Device selection and outcomes of aerosol therapy: evidence-based guildelines: American College of Chest Physicians/American College of Asthma, Allergy and Immunology. Chest 2005;127(1):335-71.
57. Wildhaber JH, Devadason SG, Wilson JM, Roller C, Lagana T, Borgstrom L, et al. Lung deposition of budesonide from Turbuhaler in asthmatic children. Eur J Pediatr 1998;157:1017-22.
58. Goren A, Novishi N, Avital A, Maayan C, Stahl E, Godfrey S, et al. Assessment of the ability of young children to use a powder inhaler device (Turbuhaler). Pediatr Pulmonol 1994;18:77-80.
59. Onhoj J, Thorsson L, Bisgaard H. Lung deposition of inhaled drugs increases with age. Am J Respir Crit Care Med 2000;162:1819-22.
60. Tal A, Golan H, Grauer N, Aviram M, Albin D, Quastrel MR. Deposition pattern of radiolabeled salbutamol inhaled from a metered-dose inhaler by means of a spacer with a mask in younger children with airway obstruction. J Pediatr 1996;128:479-84.
61. Wildhaber J, Devadson SG, Hayden MJ, Eber E, Summers QA, Le Souef PN. Aerosol delivery to wheezy infants; a comparison between nebulizers and two small volume spacers. Pediatr Pulmonol 1997;23:212-6.
62. Chua HL, Collis GG, Newbury AM, Chan K, Bower GD, Sly PD, et al. The influence of age on aerosol deposition in children with cystic fibrosis. Eur Respir J 1994;7:2185-91.
63. Wildhaber JH, Dore ND, Wilson JM, Devadason SG, Lesouef P. Inhalation therapy in asthma: nebulizer or pressurised metered-dose inhaler with holding chamber? In vivo comparison of lung deposition in children. J Pediatr 1999;135:28-33.
64. Lodrup Carlsen KC, Nikander K, Carlsen K-H. How much nebulised budesonide reaches infants and toddlers? Arch Dis Child 1992;67(9):1077-79.
65. Collis GG, Cole CH, Le Soef PN. Dilution of nebulized aerosols by air entrainment in children. Lancet 1990;336:341-3.
66. Iles R, Lister P, Edmunds AT. Crying significantly reduces absorption of aerosolised drug in infants. Arch Dis Child 1999;81:163-5.
67. Marguet C, Coudere L, Le Roux P, Jeannot E, Lefay V, Mallet E. Inhalation treatment: erors in application and difficulties in acceptance of the devices are frequent in wheezy infants and young children. Pediatr Allergy Immunol 2001;12:224-30.
68. Fok TF, Monkman S, Dolovich M, Gray S, Coates G, Paes B, et al. Efficiency of aerosol medication delivery from a metered dose inhaler versus jet nebulizer in infants with bronchopulmonary dysplasia. Pediatr Pulmonol 1996;21:301-9.
69. Mallol J, Ratttray S, Walker G, Cook D, Robertson C. Aerosol deposition in infants with cystic fibrosis. Pediatr Pulmonol 1996;21:276-81.
70. Esposito-Festen JE, Ates B, van Vliet FJ, Verbraak AF, De Jongste JC, Tiddens HA. Effect of a facemaske leak on aerosol delivery from a pMDI-spacer system. J Aerosol Med 2004;17:1-6.
71. Sangwan S, Gurses BK, Smaldone GC. Facemasks and facial deposition of aerosols. Pediatr Pulmonol 2004;37:447-52.
72. Mandelberg A, TseHori S, Houri S, Gilad E, Morag B, Priel IE. Is nebulized aerosol treatment necessary in the pediatric emergency department? Chest 2000;117(5):1309-13.
73. Delgado A, Chou KJ, Silver EJ, Crain EF. Nebulizers vs metered-dose inhalers with spacers for bronchodilator therapy to treat wheezing in children ages 2 to 24 months in a pediatric emergency department. Arch Pediatr Adolesc Med 2003;157:76-80.
74. Rubilar L, Castro-Rodriguez JA, Girardi F. Randomized trail of salbutamol via metered-dose inhaler with spacer versus nebulizer for acute wheezing in children less than 2 years of age. Pediatr Pulmonol 2000;29:264-9.
75. Closa RM, Ceballos JM, Gomez-Papi A, Galiana AS, Gutierrez C, Marti-Henneber C. Efficacy of bronchodilators administered by nebulizers versus spacer devices in infants with acute wheezing. Pediatr Pulmonol 1998;26:344-8.
76. Cates CJ, Rowe BH, Bara A. Holding chambers versus nebulizers for beta-agonist treatment of acute asthma [Cochrane review]. In: The Cochrane Library; Issue 2, 2002. Oxford: Update Software.
77. Chou KJ, Cunningham SJ, Crain EF. Metered-dose inhalers with spacers vs nebulizers for pediatric asthma. Arch Pediatr Adolesc Med 1995;149:201-4.
78. Schuh S, Johnson DW, Stephens D, Callahan S, Winders P, Canny GJ. Comparison of albuterol delivered by metered dose inhaler with spacer versus a nebulizer in children with mild acute asthma. J Pediatr 1999;135:22-7.
79. Turner MO, Garni A, Swan D, Fitzgerald JM. A review and economic evaluation of bronchodilator delivery methods in hospitalized patients. Arch Intern Med 1996;156:2113-8.
80. Loffert DT, Ikle D, Nelson HS. A comparison of commercial jet nebulizers. Chest 1994;106:1788-93.
81. Newman SP, Pellow PG, Clarke SW. Droplet size distribution of nebulised aerosols for inhalation therapy. Clin Phys Physiol Meas 1986;7:139-46.