Academic medical centers and medical research: The challenges ahead

JAMA

Volumn 294, Issue 11, 2005, Pages 1367-1372

  Cohen, Jordan J ^a   Siegel, Elisa K ^a  

^a ASSOCIATION OF AMERICAN MEDICAL COLLEGES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COST; CULTURAL FACTOR; FINANCIAL MANAGEMENT; HEALTH CARE POLICY; HEALTH INSURANCE; HUMAN; MEDICAL RESEARCH; PHYSICIAN; PRIORITY JOURNAL; REIMBURSEMENT; RESEARCH ETHICS; REWARD; TEACHING HOSPITAL; TRUST; UNIVERSITY HOSPITAL; CONFLICT OF INTEREST; ECONOMICS; ETHICS; INDUSTRY; INTERDISCIPLINARY COMMUNICATION; MANPOWER; ORGANIZATION AND MANAGEMENT; UNITED STATES;

ACADEMIC MEDICAL CENTERS; BIOMEDICAL RESEARCH; CONFLICT OF INTEREST; INDUSTRY; INTERDISCIPLINARY COMMUNICATION; RESEARCH SUPPORT; UNITED STATES;

EID: 25144477547     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.294.11.1367     Document Type: Article

References (40)

1. Association of American Medical Colleges. What Americans Say About the Nation's Medical Schools and Teaching Hospitals: Key Findings. Washington, DC: AAMC2004 Public and Congressional Staff Opinion Research Project; 2004.
2. Byers T, Byyny R. Medical science's flip-flops: news media, anxious public feed apparent contradictions. Denver Post. May 22, 2005:E-01.
3. Hwang WS, Roh SI, Lee BC, et al. Patient-specific embryonic stem cells derived from human SCNT blastocysts. Science. 2005;308:1777-1783.
4. United States Attorney's Office. US settlement of gene therapy study that ended with teen's death. Available at: http://www.usdoj.gov/usao/pae/News/Pr/ 2005/feb/UofPSettlement%20release.html. Accessed August 3, 2005.
5. Willman D. The National Institutes of Health: public servant or private marketer? Los Angeles Times. December 22, 2004;A1.
6. Office of Research Integrity Annual report 2004. Washington, DC: Dept of Health and Human Services. Available at: http://ori.dhhs.gov/documents /annual_reports/ori_annual_report_2004.pdf. Accessed August 3, 2005.
7. Association of American Medical Colleges. Protecting subjects, preserving trust, promoting progress: policy and guidelines for the oversight of individual financial interests in human subjects research. Available at: http://www.aamc.org/members/coitf /firstreport.pdf. Accessed July 20, 2005.
8. Association of American Medical Colleges. Protecting subjects, preserving trust, promoting progress, II: principles and recommendations for oversight of an institution's financial interests in human subjects research. Available at: http://www.aamc.org/members/coitf/2002coireport.pdf. Accessed July 22, 2005.
9. Association for the Accreditation of Human Research Protection Programs Inc Standards and principles. Available at: http://www.aahrpp.org. Accessed July 26, 2005.
10. Washburn J. University, Inc: The Corporate Corruption of American Higher Education. New York, NY: Basic Books; 2004.
11. Kassirer JP. On the Take: How America's Complicity With Big Business Can Endanger Your Health. New York, NY: Oxford University Press; 2005.
12. Angell M. The Truth About Drug Companies: How They Deceive Us and What to Do About It. New York, NY: Random House; 2004.
13. US Public Health Service. Responsibility of applicants for promoting objectivity in research for which PHS funding is sought. 45 CFR Subpart F (1995).
14. US Department of Health and Human Services Human subject protection: financial relationships and interests in research involving human subjects [notice]. May 12, 2004. 69 Federal Register 26393-26397 [04-10849].
15. Task Force on Research Accountability. Report on Individual and Institutional Financial Conflict of Interest: Report and Recommendations. Washington, DC: Association of American Universities; October 2001.
16. American Medical Association. E-8.0315: Managing conflicts of interest in the conduct of clinical trials. Available at: http://www.ama-assn.org/ama/pub/ category/print/8471.html. Accessed June 16, 2005.
17. American Society of Gene Therapy Policy of the American Society of Gene Therapy: financial conflict of interest in clinical research. Adopted April 5, 2000. Available at: http://www.asgt.org/position_statements/ conflict_of_interest.html. Accessed July 28, 2005.
18. Ehringhaus S, Korn D. US medical school policies on individual conflicts of interest: results of an AAMC survey. Available at: http://www.aamc.org/ members/coitf/coiresults2003.pdf. Accessed July 28, 2005.
19. The Bayh-Dole Act. Pub L 96-517.
20. Association of University Technology Managers. AUTM Licensing Survey: FY 2003. Northbrook, Ill: AUTM; 2005.
21. National Institutes of Health; US Public Health Service Principles and guidelines for recipients of NIH research grants and contracts on obtaining and disseminating biomedical research resources. December 23, 1999. 64 Federal Register 72090.
22. Davidoff F, DeAngelis CD, Drazen JM, et al. Sponsorship, authorship, and accountability. JAMA. 2001;286:1232-1233.
23. DeAngelis CD, Drazen JM, Frizelle FA, et al. Is this clinical trial fully registered? a statement from the International Committee of Medical Journal Editors. JAMA. 2005;293:2927-2929.
24. DeAngelis C, Drazen JM, Frizelle FA, et al. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. N Engl J Med. 2004;351:1250-1251.
25. National Institutes of Health Enhancing public access to archived publications resulting from NIHfunded research [notice]. February 9, 2005. 70 Federal Register 6891-6900 [05-2542].
26. Nathan DG. Clinical research, perceptions, reality, and proposed solutions. JAMA. 1998;280:1427-1431.
27. Zerhouni E. A strong foundation: building a home for clinical and translational sciences. Available at: http://www.ncrr.nih.gov/roadmap/meeting/ EZ-May23 .pdf. Accessed June 16, 2005.
28. Fishburn J National Institutes of Health in the FY 2006 Budget: AAAS Report XXX: Research and Development, FY 2006. Washington, DC: American Association for the Advancement of Science; 2005:83.
29. Executive Office of the President Office of Management and Budget, circular No. A-21: principles for determining costs applicable to grants, contracts, and other agreements with educational institutions, section G 8. Available at: http://www.whitehouse.gov/omb/circulars/ao21/a21_2004.html. Accessed July 29, 2005.
30. Report of the Working Group on the Cost of Doing Business. Council on Governmental Relations Web site. Available at: http://www.cogr.edu/docs/CODB %20FINAL%206-02-03.doc. Accessed May 26, 2005.
31. Goldman CA, Williams T. Paying for university research facilities and administration [RAND Web site]. Available at: http://www.rand.org/publications/ MR/MR1135.1. Accessed May 26, 2005.
32. US Office of Science and Technology; US Office of Management and Budget Notice on proposed policy on research and research-related grant terms and conditions. January 28, 2005. 70 Federal Register 4159-4161.
33. Baltimore D. Promoting quality and creativity in faculty and students. Paper presented at: Spring meeting of the Council of Academic Societies, Association of American Medical Colleges; October 12, 2004; Santa Monica, Calif.
34. Lander ES, Weinberg RA. Genomics: journey to the center of biology. Science. 2000;287:1777-1782.
35. Manning FJ, McGeary MG, Estabrook RW, eds. NIH Extramural Center Programs: Criteria for Initiation and Evaluation. Washington, DC: National Academies Press; 2004.
36. National Academy of Science. Facilitating Interdisciplinary Research. Washington, DC: National Academies Press; 2004.
37. Zerhouni E. Medicine: the NIH roadmap. Science.2003;302:63-72.
38. Adams JD, Black GC, Clemmons JR, Stephan PE. Scientific teams and institution collaborations: evidence from U.S. universities, 1981-1999: National Bureau of Economic Research Working Paper 10640. Available at: http://www.nber.org/papers/w10640. Accessed May 24, 2005.
39. Mallon WT, Bunton SA. Research centers and institutes at U.S. medical schools: a descriptive analysis. Acad Med. In press.
40. Marburger J. Policy concerning the treatment of principal investigators [memorandum]. Washington, DC: Executive Office of the President, Office of Science and Technology Policy; January 4, 2005.