Camptothecin binds to a synthetic peptide identified by a T7 phage display screen

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 21, 2005, Pages 4850-4853

  Takakusagi, Yoichi ^a   Kobayashi, Susumu ^a   Sugawara, Fumio ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Binding peptide; Camptothecin; QCM; SPR

Indexed keywords

ASPARAGINYLSERYLSERYLGLUTAMINYLSERYLALANYLARGINYLARGININE; CAMPTOTHECIN; CPT 20 B; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIOPHAGE T7; BINDING AFFINITY; BINDING KINETICS; BIOTINYLATION; DISSOCIATION CONSTANT; DRUG PROTEIN BINDING; PHAGE DISPLAY; PROTEIN ANALYSIS; PROTEIN BINDING; SENSOR; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BACTERIOPHAGE T7; BINDING SITES; CAMPTOTHECIN; HUMANS; MOLECULAR WEIGHT; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE;

T7 PHAGE;

EID: 25144477048     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.017     Document Type: Article

References (13)

1. A.E. Wakeling, A.J. Barker, D.H. Davies, D.S. Brown, L.R. Green, S.A. Cartlidge, and J.R. Woodburn Breast Cancer Res. Treat. 38 1996 67
2. E. Buchdunger, J. Zimmermann, H. Mett, T. Meyer, M. Muller, B.J. Druker, and N.B. Lydon Cancer Res. 56 1996 100
3. B.J. Druker, S. Tamura, E. Buchdunger, S. Ohno, G.M. Segal, S. Fanning, J. Zimmermann, and N.B. Lydon Nat. Med. 2 1996 561
4. Y. Takakusagi, K. Ohta, K. Kuramochi, K. Morohashi, S. Kobayashi, K. Sakaguchi, and F. Sugawara Bioorg. Med. Chem. Lett. 15 2005 4846
5. D.J. Rodi, R.W. Janes, H.J. Sanganee, R.A. Holton, B.A. Wallace, and L. Makowski J. Mol. Biol. 285 1999 197
6. P.P. Sche, K.M. McKenzie, J.D. White, and D.J. Austin Chem. Biol. 6 1999 707
7. Y. Jin, J. Yu, and Y.G. Yu Chem. Biol. 9 2002 157
8. J.S. Shim, J. Lee, H.J. Park, S.J. Park, and H.J. Kwon Chem. Biol. 11 2004 1455
9. T. Yamazaki, S. Aoki, K. Ohta, S. Hyuma, K. Sakaguchi, and F. Sugawara Bioorg. Med. Chem. Lett. 14 2004 4343
10. S. Aoki, K. Ohta, T. Yamazaki, F. Sugawara, and K. Sakaguchi FEBS J. 272 2005 2132
11. K. Morohashi, A. Yoshino, A. Yoshimori, S. Saito, S. Tanuma, K. Sakaguchi, and F. Sugawara Biochem. Pharmacol. 70 2005 37
12. Y. Okahata, K. Niikura, Y. Sugiura, M. Sawada, and T. Morii Biochemistry 37 1998 5666
13. H. Matsuno, K. Niikura, and Y. Okahata Chemistry 7 2001 3305