Increased oxygen consumption caused by cAMP- and Ca2+-mediated chloride secretion in rat distal colon

Acta Gastroenterologica Latinoamericana

Volumn 35, Issue 1, 2005, Pages 13-18

  Saraví, Fernando D ^a,b   Cincunegui, Liliana M ^a   Saldeña, Teobaldo A ^a   Carra, Graciela E ^a   Ibáñez, Jorge E ^a  

^a UNIVERSIDAD NACIONAL DE CUYO   (Argentina)

^b FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

Chloride secretion; Descending colon; Oxygen consumption

Indexed keywords

CALCIUM; CARBACHOL; CHLORIDE; CYCLIC AMP; ISOBUTYLMETHYLXANTHINE; MUSCARINIC AGENT; SEROTONIN;

ANIMAL; ARTICLE; COLON; DRUG INTERACTION; INTESTINE MUCOSA; MALE; METABOLISM; OXYGEN CONSUMPTION; PHYSIOLOGY; RAT; WISTAR RAT;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; CALCIUM; CARBACHOL; CHLORIDES; COLON; CYCLIC AMP; DRUG INTERACTIONS; INTESTINAL MUCOSA; MALE; MUSCARINIC AGONISTS; OXYGEN CONSUMPTION; RATS; RATS, WISTAR; SEROTONIN;

EID: 25144473963     PISSN: 03009033     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Mandel LJ, Balaban RS. Stoichiometry and coupling of active transport to oxidative metabolism in epithelial tissues. Am J Physiol 1981;240:F357-F371.
2. Silverthorn SU, Eaton DC. Respiration and sodium transport in rabbit urinary bladder. Biochim Biophys Acta 1982;689:299-308.
3. Welsh MJ. Energetics of chloride secretion in canine tracheal epithelium. Comparison of the metabolic cost of chloride transport with the metabolic cost of sodium transport. J Clin Invest 1984;74:262-268.
4. Soltoff SP. Coupling renal metabolism to ion transport in renal epithelia. Semin Nephrol 1987;7:20-28.
5. Durand J, Durand-Arczynska W, Wankmiller D. Coupling of active sodium transport to oxidative metabolism in rabbit distal colon. J Physiol (London) 1988;396:55-64.
6. Saraví FD, Saldeña TA, Cincunegui LM. Colon epithelial electrical responses to acute hypoxia and reoxygenation in vitro. Acta Gastroenterol Latinoam 1996;26:159-165.
7. Hinterleitner TA, Valentich JD, Cha JH, Will P, Welton A, Powell DW. Platelet-activating factor contributes to immune cell and oxidant-mediated intestinal secretion. J Pharmacol Exp Ther 1997;281:1264-1271.
8. Saraví FD, Saldeña TA, Tonn EF, Cincunegui LM, Carra GM, Ibáñez JE. Sodium-deprived rat distal colon epithelial response to acute hypoxia and reoxygenation. Acta Gastroenterol Latinoam 2001;31:123-130.
9. Vahl AC. Endoluminal pulse oximetry in the sigmoid colon: An experimental study in pigs and a prospective study in patients after aortic grafting. Amsterdam: VU University Press, 1994.
10. Burns BJ, Brandt LJ. Intestinal ischemia. Gastroenterol Clin North Am 2003;32:1127-1143.
11. Chan KL, Ng SP, Chan KW, Wo YH, Tam PKH. Pathogenesis of neonatal necrotizing enterocolitis: a study of the role of intraluminal pressure, age and bacterial concentration. Pediatr Surg Int 2003;19:573-577.
12. Olson DW, Jijon H, Madsen KL, Al-Saghier M, Zeng J, Jewell LD, Bigam DL, Churchill TA. Human small bowel storage: the role for luminal preservation solutions. Transplantation 2003;76:709-714.
13. Saraví FD, Saldeña TA, Carrera CA, Ibáñez JE, Cincunegui LM, Carra GE. Oxygen consumption and chloride secretion in rat distal colon isolated mucosa. Digest Dis Sci 2003;48:1767-1773.
14. Bern MJ, Sturbaum CW, Karayalcin SS, Berschneider HM, Wachsman JT, Powell DW. Immune system control of rat and rabbit colonic electrolyte transport. Role of prostaglandins and enteric nervous system. J Clin Invest 1989;83:1810-1820.
15. Hörger S, Schultheiss G, Diener M. Segment-specific effects of epinephrine on ion transport in the colon of the rat. Am J Physiol 1998;275:G1367-G1376.
16. Eto B, Boisset M, Griesmar B, Desjeux JF. Effect of sorbin on electrolyte transport in rat and human intestine. Am J Physiol 1999;276:G107-G114.
17. Condliffe SB, Doolan CM, Harvey BJ. 17 beta-Oestradiol acutely regulates Cl- secretion in rat distal colon epithelium. J Physiol (London) 2001;530:47-54.
18. Saldeña TA, Sasso AJC, Cincunegui LM, Carra GE, Codina MV, Saraví FD. Pharmacological suppression of rat distal colon chloride transport requires two blockers. Acta Gastroenterol Latinoam 2003;33:119-127.
19. Barrett KE, Keely SJ. Chloride secretion by the intestinal epithelium: molecular basis and regulatory aspects. Annu Rev Physiol 2000;62:535-572.
20. Kunzelmann K, Mall M. Electrolyte transport in the mammalian colon: Mechanisms and implications for disease. Physiol Rev 2002;82:245-289.
21. Ning Y, Zhu JX, Chan HC. Regulation of ion transport by 5-hydroxytryptamine in rat colon. Clin Exp Pharmacol Physiol 2004;31:424-428.
22. Budhoo MR, Harris RP, Kellum JM. 5-Hydroxytryptamine-induced Cl- transport is mediated by 5-HT3 and 5-HT4 receptors in the rat distal colon. Eur J Pharmacol 1996;298:137-144.
23. Albuquerque FC Jr, Smith EH, Kellum JM. 5-HT induces cAMP production in crypt colonocytes at a 5-HT4 receptor. J Surg Res 1998;77:137-140.
24. Brzuszczak IM, Zhao J, Bell C, Stiel D, Fielding I, Percy J, Smith R, O'Loughlin EV. Cyclic AMP-dependent anion secretion in human small and large intestine. J Gastroenterol Hepatol 1996;11:804-810.
25. Schultz BD, Singh AK, Devor DC, Bridges RJ. Pharmacology of CFTR chloride channel activity. Physiol Rev 1999; 79 (Suppl):S109-S144.
26. Warth R, Riedemann N, Bleich M, Van Driessche W, Busch AE, Greger R. The cAMP-regulated and 293B-inhibited K+ conductance of rat colonic crypt base cells. Pflügers Arch 1996;432: 81-88.
27. Mall M, Bleich M, Schurlein M, Kuhr J, Seydewitz HH, Brandis M, Greger R, Kunzelmann K. Cholinergic ion secretion in human colon requires coactivation by cAMP. Am J Physiol 1998;275:G1472-G1281.
28. Schultheiss G, Ribeiro R, Schäfer KH, Diener M. Activation of apical K+ conductances by muscarinic receptor stimulation in rat distal colon: fast and slow components. J Membrane Biol 2003;195:183-196.
29. Fuller CM, Benos DJ. Ca2+-activated Cl- channels: A newly emerging anion transport family. News Physiol Sci 2000;15:165-171.
30. Sánchez de Medina F, Pérez R, Martínez-Augustin O, González R, Lorente MD, Gálvez J, Zarzuelo A. Disturbances of colonic ion secretion in inflammation: role of the enteric nervous system and cAMP. Pflügers Arch 2002;444:378-388.