Interaction of serotonin with Candida albicans selectively attenuates fungal virulence in vitro

International Journal of Antimicrobial Agents

Volumn 26, Issue 4, 2005, Pages 335-337

  Mayr, A ^a   Hinterberger, G ^a   Dierich, M P ^a   Lass Florl C ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

5 Hydroxytryptamine (5 HT); Antifungal activity; Candida albicans; Virulence factor

Indexed keywords

PHOSPHOLIPASE; SEROTONIN;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; DRUG EFFECT; ENZYME ACTIVITY; FUNGAL VIRULENCE; FUNGUS HYPHAE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

ASPARTIC ENDOPEPTIDASES; CANDIDA ALBICANS; FREE RADICAL SCAVENGERS; HYPHAE; MICROBIAL SENSITIVITY TESTS; PHOSPHOLIPASES; SEROTONIN; VIRULENCE FACTORS;

EID: 25144447742     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2005.07.006     Document Type: Article

References (18)

1. R. Mössner, and K.P. Lesch Role of serotonin in the immune system and in neuroimmune interactions Brain Behav Immun 12 1998 249 271
2. K. Hellstrand, and S. Hermodsson Serotonergic 5-HT1A receptors regulate a cell contact-media interaction between natural killer cells and monocytes Scand J Immunol 37 1993 7 18
3. W.B. Essmann Serotonin distribution in tissue and fluids 1991 Spectrum New York, NY
4. H. Holmsen, and H.J. Weiss Secretable storage pools in platelets Annu Rev Med 30 1979 119 134
5. C. Lass-Flörl, D. Fuchs, M. Ledochowski, C. Speth, M.P. Dierich, and R. Würzner Antifungal properties of 5-hydroxytryptamine (serotonin) against Candida species in vitro J Med Microbiol 52 2003 169 171
6. P. Schuff-Werner, and W. Splettstoesser Antioxidative properties of serotonin and the bactericidal function of polymorphonuclear phagocytes G. Huether T. Kochen T.J. Simat H. Steinhart Tryptophan, serotonin and melaton: basic aspects and applications 1999 Kluwer Academic Plenum Publishers New York, NY
7. National Committee for Clinical Laboratory Standards. Reference method for broth dilution antifungal susceptibility testing of yeasts, document M 27-A. Villanova, PA: NCCLS; 1995.
8. A. Gruber, E. Lukasser-Vogl, M. Borg-von Zepelin, M.P. Dierich, and R. Würzner Human immunodeficiency virus type 1 gp160 and gp41 binding to Candida albicans selectively enhances candidal virulence in vitro J Infect Dis 177 1998 1057 1063
9. M.W. Ollert, C. Wende, and M. Gorlich Increased expression of Candida albicans secretory proteinase, a putative virulence factor, in isolates from human immunodeficiency virus-positive patients J Clin Microbiol 33 2001 2543 2549
10. J.D. Sobel, G. Muller, and H.R. Buckley Critical role of germ tube formation in the pathogenesis of candidal vaginitis Infect Immun 44 1984 576 580
11. D.W. Denning Invasive aspergillosis Clin Infect Dis 26 1998 781 803
12. M.A. Ghannoum Potential role of phospholipases in virulence and fungal pathogenesis Clin Microbiol Rev 13 2000 122 143
13. M. Birch, G. Robson, D. Law, and D. Denning Evidence of multiple extracellular phospholipase activities of Aspergillus fumigatus Infect Immun 64 1996 751 755
14. A. Salyers, and D. Witt Virulence factors that promote colonization A. Salyers D. Witt Bacterial pathogenesis: a molecular approach 1994 ASM Press Washington, DC
15. M. Schaller, B. Hube, and M.W. Ollert In vivo expression and localisation of Candida albicans secreted aspartyl proteinases during oral candidiasis in HIV-infected patients J Invest Dermatol 112 2001 383 386
16. T.C. White, and N. Agabian Candida albicans secreted aspartyl proteinases: isoenzyme pattern is determined by cell type, and levels are determined by environmental factors J Bacteriol 177 2001 5215 5221
17. J. Tu, and H. Zellweger Blood-5-HT deficiency in Down syndrome Lancet 11 1965 715 716
18. M. Larsson, L. Hagberg, G. Norkans, and A. Forsman Indole amine deficiency in blood and cerebrospinal fluid from patients with human immunodeficiency virus infection J Neurosci Res 23 1989 441 446