GATA-2 and HNF-3β regulate the human alcohol dehydrogenase 1A (ADH1A) gene

DNA and Cell Biology

Volumn 24, Issue 9, 2005, Pages 543-552

  Dannenberg, Luke O ^a   Chen, Hui Ju ^a   Edenberg, Howard J ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE 1A; CIS ACTING ELEMENT; HEPATOCYTE NUCLEAR FACTOR 3; HEPATOCYTE NUCLEAR FACTOR 3BETA; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG;

ADH1A GENE; ALCOHOL METABOLISM; ANIMAL CELL; ARTICLE; CELL LINE; CELL STRAIN CV 1; CELL STRAIN H4IIE C3; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE; GENE CONTROL; GENETIC TRANSCRIPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; RAT; TISSUE SPECIFICITY; TRANSLATION INITIATION;

ALCOHOL DEHYDROGENASE; CELL LINE; DNA FOOTPRINTING; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GATA2 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; OLIGONUCLEOTIDES; REGULATORY ELEMENTS, TRANSCRIPTIONAL;

EID: 25144442698     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.2005.24.543     Document Type: Article

References (37)

1. BESNARD, V., WERT, S.E., HULL, W.M., and WHITSETT, J.A. (2004). Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues. Gene Expr. Patterns 2, 193-208.
2. BOSRON, W.F., EHRIG, T., and LI, T.K. (1993). Genetic factors in alcohol metabolism and alcoholism. Semin. Liver Dis. 13, 126-135.
3. BROWN, C.J., ZHANG, L., and EDENBERG, H.J. (1994). Tissue-specific differences in the expression of the human ADH2 alcohol dehydrogenase gene and in binding of factors to cis-acting elements in its promoter. DNA Cell Biol. 13, 235-247.
4. BROWN, C.J., ZHANG. L., and EDENBERG, H.J. (1996). Gene expression in a young multigene family: Tissue-specific differences in the expression of the human alcohol dehydrogenase genes ADH1, ADH2, and ADH3. DNA Cell Biol. 15, 187-196.
5. BULUN, S.E., SEBASTIAN, S., TAKAYAMA, K., SUZUKI, T., SASANO, H., and SHOZU, M. (2003). The human CYP19 (aromatase P450) gene: Update on physiologic roles and genomic organization of promoters. J. Steroid Biochem. Mol. Biol. 86, 219-224.
6. CARTHEW, R.W., CHODOSH, L.A., and SHARP, P.A. (1985). An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell 43, 439-448.
7. CEREGHINI, S. (1996). Liver-enriched transcription factors and hepatocyte differentiation. FASEB J. 10, 267-282.
8. CHEN, H.-J., CARR, K., JEROME, R.E., and EDENBERG, H.J. (2002). A retroviral repetitive element confers tissue-specificity to the human alcohol dehydrogenase 1C (ADH1C) gene. DNA Cell Biol., 21, 793-801.
9. CLARK, K.L., HALAY, E D., LAI, E., and BURLEY, S.K. (1993). Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364, 412-420.
10. COSTA, R.H., GRAYSON, D.R., and DARNELL, J.E., JR. (1989). Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes. Mol. Cell. Biol. 9, 1415-1425.
11. DORFMAN, D.M., WILSON, D.B., BRUNS, G.A., and ORKIN, S.H. (1992). Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells. J. Biol. Chem. 267, 1279-1285.
12. EDENBERG, H.J. (2000). Regulation of the mammalian alcohol dehydrogenase genes. Prog. Nucleic Acid Res. Mol. Biol. 64, 295-341.
13. EDENBERG, H.J., and BROWN, C.J. (1992). Regulation of human alcohol dehydrogenase genes. Pharmacogenetics 2, 185-196.
14. EDENBERG, H.J., and JEROME, R.E. (2000). Mapping of the human alcohol dehydrogenase genes: ADH7 is adjacent to the ADH1-ADH2-ADH3 cluster. Alcohol Clin. Exp. Res. 24(Suppl.), 26A.
15. EDENBERG, H.J., BROWN, C.J., and ZHANG, L. (1994). Alcohol dehydrogenases: Molecular biology and gene regulation. Alcohol Suppl. 2, 121-125.
16. GAO, N., ZHANG, J., RAO, M.A., CASE, T.C., MIROSEVICH, J., WANG, Y., JIN, R., GUPTA, A., RENNIE, P.S., and MATUSIK, R.J. (2003). The role of hepatocyte nuclear factor-3α (forkhead box A1) and androgen receptor in transcriptional regulation of prostatic genes. Mol. Endocrinol. 17, 1484-1507.
17. HEINEMEYER, T., WINGENDER, E., REUTER, I., HERMJAKOB, H., KEL, A.E., KEL, O.V., IGNATIEVA, E.V., ANANKO, E.A., PODKOLODNAYA, O.A., KOLPAKOV, F.A., et al. (1998). Data-bases on transcriptional regulation: TRANSFAC, TRRD, and COMPEL. Nucleic Acids Res. 26, 364-370.
18. MARTIN, D.I.K., and ORKIN, S.H. (1990). Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf1. Genes Dev. 4, 1886-1898.
19. MINEGISHI, N., OHTA, J., YAMAGIWA, H., SUZUKI, N., KAWAUCHI, S., ZHOU, Y., TAKAHASHI, S., HAYASHI, N., ENGEL, J.D., and YAMAMOTO, M. (1999). The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region. Blood 12, 4196-4207.
20. MIYAMOTO, N.G., MONCOLLIN, V., EGLY, J.M., and CHAMBON, P. (1985). Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter. EMBO J. 4, 3563-3570.
21. NORDEEN, S.K. (1988). Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6, 454-458.
22. OVERDIER, D.G., PORCELLA, A., and COSTA, R.H. (1994). The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helix. Mol. Cell. Biol. 14, 2755-2766.
23. PHILIPPE, J., MOREL, C., and PREZIOSO, V.R. (1994). Glucagon gene expression is negatively regulated by hepatocyte nuclear factor 3 beta. Mol. Cell. Biol. 14, 3514-3523.
24. SAWADOGO, M., and ROEDER, R.G. (1985). Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell 43, 165-175.
25. SMITH, M. (1986). Genetics of human alcohol and aldehyde dehydrogenases. Adv. Hum. Genet. 15, 249-290.
26. SMITH, M., HOPKINSON, D.A., and HARRIS, H. (1971). Developmental changes and polymorphism in human alcohol dehydrogenase. Ann. Hum. Genet. 34, 251-271.
27. SMITH, M., HOPKINSON, D.A., and HARRIS, H. (1972). Alcohol dehydrogenase isozymes in adult human stomach and liver: Evidence for activity of the ADH3 locus. Ann. Hum. Genet. 35, 243-253.
28. SMITH, M., HOPKINSON, D.A., and HARRIS, H. (1973). Studies on the properties of the human alcohol dehydrogenase isozymes determined by the different loci ADH1, ADH2, ADH3. Ann. Hum. Genet. Lond. 37, 49-67.
29. STEWART, M.J., MCBRIDE, M.S., WINTER, L.A., and DUESTER, G. (1990a). Promoters for the human alcohol dehydrogenase genes ADH1, ADH2, and ADH3: Interaction of CCAAT/enhancer-binding protein with elements flanking the ADH2 TATA box. Gene 90, 271-279.
30. STEWART, M.J., SHEAN, M.L., and DUESTER, G. (1990b). trans Activation of human alcohol dehydrogenase gene expression in hepatoma cells by C/EBP molecules bound in a novel arrangement just 5′ and 3′ to the TATA box. Mol. Cell. Biol. 10, 5007-5010.
31. VAN OOIJ, C., SNYDER, R.C., PAEPER, B.W., and DUESTER, G. (1992). Temporal expression of the human alcohol dehydrogenase gene family during liver development correlates with differential promoter activation by hepatocyte nuclear factor 1, CCAAT/enhancer binding protein α, liver activator protein, and D-element-binding protein. Mol. Cell. Biol. 12, 3023-3031.
32. WADE, D.P., PUCKEY, L.H., KNIGHT, B.L., ACQUATI, F., MIHALICH, A., and TARAMELLI, R. (1997). Characterization of multiple enhancer regions upstream of the apolipoprotein(a) gene. J. Biol. Chem. 272, 30387-30399.
33. WANG, N.D., FINEGOLD, M.J., BRADLEY, A., OU, C.N., ABDELSAYED, S.V., WILDE, M.D., TAYLOR, L.R., WILSON, D.R., and DARLINGTON, G.J. (1995). Impaired energy homeostasis in C/EBP alpha knock-out mice. Science 246, 911-916.
34. WOLFLA, C.E., ROSS, R.A., and CRABB, D.W. (1988). Induction of alcohol dehydrogenase activity and mRNA in hepatoma cells by dexamethasone. Arch. Biochem. Biophys. 263, 69-76.
35. YASUNAMI, M., KIKUCHI, I., SARAPATA, D., and YOSHIDA, A. (1990). The human class I alcohol dehydrogenase gene cluster: Three genes are tandemly organized in an 80-kb-long segment of the genome. Genomics 7, 152-158.
36. YINDEEYOUNGYEON, W., and SCHELL, M.A. (2000). Footprinting with an automated capillary DNA sequencer. Biotechniques 29, 1034-1036, 1038, 1040-1041.
37. ZHANG, S.B., HE, Q.Y., ZHAO, H., GUI, C.Y., JIANG, C., and QIAN, R.L. (2001). Function of GATA transcription factors in hydroxurea-induced HEL cells. Cell Res. 11, 301-310.