Pesticides and essential minerals modify endogenous antioxidants and cytochrome P450 in tissues of rats

Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes

Volumn 40, Issue 5, 2005, Pages 769-784

  Bebe, Frederick N ^a   Panemangalore, Myna ^a  

^a KENTUCKY STATE UNIVERSITY   (United States)

Author keywords

Calcium; Copper; Cytochrome P450; Glutathione; Glutathione peroxidase; Pesticides; Rats; Superoxide dismutase; Zinc

Indexed keywords

ANTIOXIDANTS; CALCIUM; CONCENTRATION (PROCESS); COPPER; ENZYMES; PEST CONTROL; ZINC;

CYTOCHROME P450; GLUTITHIONE PEROXIDASE; RATS; SUPEROXIDE DISMUTASE;

PESTICIDES;

ACEPHATE; ANTIOXIDANT; CALCIUM; COPPER; CYTOCHROME P450; ENDOSULFAN; ETHOXYRESORUFIN DEETHYLASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MINERAL; PESTICIDE; SUPEROXIDE DISMUTASE; THIRAM; ZINC;

ANTIOXIDANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; DIET; DIETARY INTAKE; ENZYME ACTIVITY; ERYTHROCYTE; FOOD INTAKE; LD 50; LIVER; NONHUMAN; PLASMA; RAT; SMALL INTESTINE; WEIGHT GAIN;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INTESTINAL MUCOSA; LIVER; MALE; PESTICIDES; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE;

EID: 24944588767     PISSN: 03601234     EISSN: None     Source Type: Journal    
DOI: 10.1080/03601230500189709     Document Type: Article

References (34)

1. Klaunig, J.E.; Xu, Y.; Isenberg, J.S.; Bachowski, S.; Kolaja, K.L.; Kiang, J.; Stevenson, D.; Salborg, E.F., Jr. The role of oxidative stress in chemical carcinogenesis. Environ. Health Persp. 1998, 106, 289-295.
2. Ray, D.E.; Richards, P.G. The potential for toxic effects of chronic, low-dose exposure to organophosphates. Toxicol. Lett. 2001, 120, 343-351.
3. Tordoir, W.F.; Sittert, N.J. Organochlorines. Toxicology 1994, 91, 51-57.
4. Gupta, R.C. Carbofuran toxicity. J. Toxicol. Environ. Health 1994, 43, 383-418.
5. Heidli C.C.; Snyder R.; Kinoshita, R.; Steinberg, N. Investigation of cytochrome P-450 enzyme induction and DNA adduct formation in male CD/1 mice following oral administration of toxophene. J. Appl. Toxicol. 1998, 18, 173-178.
6. Janssen, Y.M.N.; Van Houton, B.; Bonn, P.J.A.; Mossman, B.T. Cell and tissue responses to oxidative stress. Lab. Invest. 1993, 69, 261-274.
7. Banks, D.; Soliman, M.R. Protective effects of antioxidants against benomyl-induced lipid peroxidation and glutathione depletion in rats. Toxicology 1997, 116, 177-181.
8. Panemangalore, M.; Bebe, F.N. Dermal exposure to pesticides modifies antioxidant enzymes in tissues of rats. J. Environ. Sci. Health 2000, B35, 399-416.
9. Bebe, F.N.; Panemangalore, M. Exposure to low doses of endosulfan and chlorpyrifos modifies endogenous antioxidants in tissues of rats. J. Environ. Sci. Health 2003, B38, 349-363.
10. Panemangalore, M.; Bebe, F.N. Effect of high dietary zinc on plasma ceruloplasmin nd erythrocyte superoxide dismutase in copper depleted and repleted rats. Biol. Trace Elem. Res. 1996, 55, 111-126.
11. Alaimo, K.; McDowell, M.A.; Briefel, R.R.; Bischof, A.M.; Caughman, C.R.; Loria, C.M.; Johnson, C.L. Dietary Intake of Mineral, Vitamins and Fiber of Persons Aged 2 Months and Over in the United States: Third National Health and Nutrition Examination Survey, Phase I, 1988-1991. Bulletin 258, DHHS (PHS), publication number 95-1250-4-2511; National Center for Health Statistics, U.S. Department for Health and Human Services: Hyattsville, MD, 1994.
12. Budavari, S.; O'Neil, M.J.; Smith, A.; Heckelman, P.E.; Kinneary, J.F., Eds.; The Merck Index, 12th Ed.; Merck Research Laboratories: Whitehouse Station, NJ, 1996.
13. ATSDR: Agency for Toxic Substances and Disease Registry. Toxic Profile for Endosulfan, 22-26. U.S. Department of Health and Human Services, Public Health Service: Atlanta, GA, 2000.
14. Reeves, P.G.; Nielson, F.H.; Fahey, G.G. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on reformulation of the 1976 rodent diet. J. Nutr. 1993, 123, 1939-1951.
15. Sun, Y.; Oberley, LW.; Li, Y. A simple clinical assay of superoxide dismutase. Clin. Chem. 1988, 34, 497-500.
16. Smith, P.K.; Krohn, R.L.; Hermanson, G.T.; Mallia, A.K.; Gartner, F.H.; Provenzano, M.D.; Fujimoto, E.K.; Goeke, N.M.; Olson B.J.; Klenk, D.C. Measurement of protein using bicinchoninic acid. Anal. Biochem. 1985, 150, 76-85.
17. Flohé, L.; Gunzler, W.A. Assay of glutathione peroxidase. Methods Enzymol. 1984, 105, 114-120.
18. Baker, M.A.; Cerniglia, G.J.; Zaman, A. Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples. Anal. Biochem. 1990, 190, 360-365.
19. Lubet, R.A.; Mayer, R.T.; Cameron, J.W.; Nims, R.W.; Burke, D.M.; Wolfe, T.; Guengerich, P.F. Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. Arch. Biochem. Biophys. 1985, 238, 43-48.
20. Azzalis, L.A.; Junquiera, V.B.C.; Simon, K.; Giavarotti, L.; Silva, M.A.; Simizu, K.; Barros, S.B.M.; Farga, C.; Porta, E.A. Prooxidant and antioxidant hepatic factors in rats chronically fed an ethanol regimen and treated with an acute dose of lindane. Free Radic. Biol. Med. 1995, 19, 147-159.
21. Junqueira, V.B.C.; Kosh, O.R.; Arisi, A.C.; Fusaro, A.P.; Azzalis, L.A.; Barros, S.B.; Cravero, A.; Farre, S.; Videla, L.A. Regression of morphological alterations and oxidative stress-related parameters after acute lindane-induced hepatotoxicity in rats. Toxicology 1997, 111, 199-205.
22. Nasuti, C.; Cantalamessa, F.; Falcioni, G.; Gabbianelli, R. Different effects of Type I and Type II pyrethroids on erythrocyte plasma membrane properties and enzymatic activities in rats. Toxicology 2003, 191, 233-244.
23. DiSilvestro, R.A. Copper activation of superoxide dismutase in rat erythrocytes. Arch. Biochem. Biophys. 1989, 274, 298-303.
24. Gabbianelli, R.; Falcioni, G.; Nasuti, C.; Cantalamessa, F. Cypermethrin-induced plasma membrane perturbation on erythrocytes from rats: Reduction of fluidity in the hydrophobic core and in glutathione peroxidase activity. Toxicology 2002, 175, 91-101.
25. Gultekin, F.; Ozturk, M.; Akdogan, M. The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro). Arch. Toxicol. 2000, 74, 533-538.
26. Brigelius-Flohé, R. Tissue specific functions of individual glutathione peroxidases. Free Radic. Biol. Med. 1999, 27, 951-965.
27. Klotz, L.; Kroncke, K.; Buchczyk, D.P.; Sies, H. Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress. J. Nutr. 2003, 133, 1448S-1451S.
28. Sies, H. Glutathione and its role in cellular functions. Free Radic. Biol. Med. 1999, 27, 916-921.
29. Lu, S.C. Regulation of glutathione synthesis. In Current Topics in Cellular Regulation, Vol. 36; Stadtman, E.R., Chock, P.B., Eds.; Academic Press: San Diego, CA, 2000; 95-116.
30. Mahboob, M.; Siddiqui, M.K. Alterations in hepatic detoxifying enzymes by new organophosphorus insecticides following sub-chronic exposure in rats. J. Appl. Toxicol. 2001, 21 (6), 501-505.
31. Guengerich, F.P. Influence of nutrients and other dietary material on cytochrome P-450 enzymes. Am. J. Clin. Nutr. 1995, 61, 951S-958S.
32. Vakharia, D.D.; Liu, N.; Pause, R.; Fasco, M.; Bessette, E.; Zhang, Q.Y.; Kaminsky, L.S. Effects of metals on polycyclic aromatic hydrocarbon induction of CYP1A1 and CYP1A2 in human hepatocyte cultures. Toxicol. Appl. Pharmacol. 2001, 170, 93-103.
33. Gallo, M.A.; Lawryk, N.J. Organophosphorus pesticides. In Handbook of Pesticide Toxicology, Vol. 2; Hayes, E.J., Laws, E. R., Eds.; Academic Press: San Diego, CA, 1991; 917-1123.
34. Panemangalore, M.; Bebe, F.N. Interaction between pesticides and essential metals modifies tissue copper homeostasis in rats. Biol. Trace. Elem. Res. 2005, 70 (in press).