Prophylaxis for invasive candidiasis in the intensive care unit: Is it time?

Critical Care Medicine

Volumn 33, Issue 9, 2005, Pages 2121-2122

  Ostrosky Zeichner, Luis ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Fluconazole; Intensive care unit, prophylaxis; Invasive candidiasis; Meta analysis

Indexed keywords

FLUCONAZOLE;

CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDIASIS; CLINICAL TRIAL; DRUG CHOICE; EDITORIAL; ENVIRONMENTAL PROTECTION; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; META ANALYSIS; PRIORITY JOURNAL; PROPHYLAXIS; RISK ASSESSMENT; SYSTEMATIC REVIEW;

EID: 24944578687     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000178342.24744.82     Document Type: Editorial

References (24)

1. Shorr AF, Chung K, Jackson WL, et al: Fluconazole prophylaxis in critically ill surgical patients: A meta-analysis. Crit Care Med 2005; 33:1928-1935
2. Jarvis WR: Epidemiology of nosocomial fungal infections, with emphasis on Candida species. Clin Infect Dis 1995; 20:1526-1530
3. Rangel-Frausto MS, Wiblin T, Blumberg HM, et al: National epidemiology of mycoses survey (NEMIS): Variations in rates of bloodstream infections due to Candida species in seven surgical intensive care units and six neonatal intensive care units. Clin Infect Dis 1999; 29:253-258
4. Blumberg HM, Jarvis WR, Soucie JM, et al: Risk factors for candidal bloodstream infections in surgical intensive care unit patients: The NEMIS prospective multicenter study. The National Epidemiology of Mycosis Survey. Clin Infect Dis 2001; 33:177-186
5. Diekema DJ, Messer SA, Brueggemann AB, et al: Epidemiology of candidemia: 3-Year results from the emerging infections and the epidemiology of Iowa organisms study. J Clin Microbiol 2002; 40:1298-1302
6. Blot SI, Vandewoude KH, Hoste EA, Colardyn FA: Effects of nosocomial candidemia on outcomes of critically ill patients. Am J Med 2002; 113:480-485
7. Gudlaugsson O, Gillespie S, Lee K, et al: Attributable mortality of nosocomial candidemia, revisited. Clin Infect Dis 2003; 37:1172-1177
8. Rentz AM, Halpern MT, Bowden R: The impact of candidemia on length of hospital stay, outcome, and overall cost of illness. Clin Infect Dis 1998; 27:781-788
9. Sobel JD, Rex JH: Invasive candidiasis: Turning risk into a practical prevention policy? Clin Infect Dis 2001; 33:187-190
10. Garbino J, Lew DP, Romand JA, et al: Prevention of severe Candida infections in non-neutropenic, high-risk, critically ill patients: A randomized, double-blind, placebo-controlled trial in patients treated by selective digestive decontamination. Intensive Care Med 2002; 28:1708-1717
11. Eggimann P, Francioli P, Bille J, et al: Fluconazole prophylaxis prevents intra-abdominal candidiasis in high-risk surgical patients. Crit Care Med 1999; 27:1066-1072
12. Pelz RK, Hendrix CW, Swoboda SM, et al: Double-blind placebo-controlled trial of fluconazole to prevent candidal infections in critically ill surgical patients. Ann Surg 2001; 233:542-548
13. Pappas PG, Rex JH, Sobel JD, et al: Guidelines for treatment of candidiasis. Clin Infect Dis 2004; 38:161-189
14. Wenzel RP: Nosocomial candidemia: risk factors and attributable mortality. Clin Infect Dis 1995; 20:1531-1534
15. Garbino J, Kolarova L, Rohner P, et al: Secular trends of candidemia over 12 years in adult patients at a tertiary care hospital. Medicine (Baltimore) 2002; 81:425-433
16. Pappas PG, Rex JH, Lee J, et al: A prospective observational study of candidemia: Epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients. Clin Infect Dis 2003; 37:634-643
17. Snydman DR. Shifting patterns in the epidemiology of nosocomial Candida infections. Chest 2003;123:500S-503S.
18. Rex JH, Sobel JD: Prophylactic antifungal therapy in the intensive care unit. Clin Infect Dis 2001; 32:1191-1200
19. National Institute of Allergy and Infectious Disease. Caspofungin study. http://clinicaltrials.gov/ct/show/NCT00095316?order=1
20. Ostrosky-Zeichner L, Sable C, Sobel J, et al: Multicenter retrospective development and validation of a clinical prediction rule for invasive candidiasis (IC) in the intensive care setting. Abstr. 51. In: Focus on Fungal Infections 14, New Orleans, LA, 2004
21. Paphitou NI, Ostrosky-Zeichner L, Rex JH: Rules for identifying patients at increased risk for candidal infections in the surgical intensive care unit: An approach to developing practical criteria for systematic use in antifungal prophylaxis trials. Med Mycol 2005; 43:235-243
22. Piarroux R, Grenouillet F, Balvay P, et al: Assessment of pre-emptive treatment to prevent severe candidiasis in critically ill surgical patients. Crit Care Med 2004; 32:2443-2449
23. Dupont H, Bourichon A, Paugam-Burtz C, et al: Can yeast isolation in peritoneal fluid be predicted in intensive care unit patients with peritonitis? Crit Care Med 2003; 31:752-757
24. De Waele JJ, Vogelaers D, Blot S, et al: Fungal infections in patients with severe acute pancreatitis and the use of prophylactic therapy. Clin Infect Dis 2003; 37:208-213.