Augmented humoral and cellular immune responses to hepatitis B DNA vaccine adsorbed onto cationic microparticles

Journal of Controlled Release

Volumn 107, Issue 2, 2005, Pages 357-372

  He, Xiaowen ^a   Jiang, Lei ^a   Wang, Fang ^a   Xiao, Zhenyu ^a   Li, Jun ^b   Liu, Shankui Liu ^a   Li, Dean ^a   Ren, Ding ^a   Jin, Xiaoqin ^b   Li, Kai ^a   He, Yin ^a   Shi, Ke ^a   Guo, Yingjun ^a   Zhang, Yanan ^a   Sun, Shuhan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b NAVAL MEDICAL RESEARCH INSTITUTE   (China)

Author keywords

Cetyltrimethylammonium bromide; DNA vaccine; HBsAg; Hepatitis B virus; Immunogenicity; Poly(lactide co glycolide acid) microparticle

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; CYTOLOGY; IMMUNOLOGY; NEAR FIELD SCANNING OPTICAL MICROSCOPY; VIRUSES;

CETYLTRIMETHYLAMMONIUM BROMIDE; DNA VACCINE; HBSAG; HEPATITIS B VIRUS; IMMNOGENECITY; POLY (LACTIDE-CO-GLYCOLIDE-ACID) (PLGA);

DNA SEQUENCES;

CATION; CETRIMIDE; DNA VACCINE; GAMMA INTERFERON; GLYCOPROTEIN P 15095; HEPATITIS B SURFACE ANTIGEN; NAKED DNA; PLASMID DNA; POLYGLACTIN; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVITY; CELL TRANSPLANTATION; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONFOCAL LASER MICROSCOPY; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DRUG ADSORPTION; DRUG RELEASE; FEMALE; FLOW CYTOMETRY; HEPATITIS B; HUMORAL IMMUNITY; IMMUNITY; IMMUNIZATION; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE; MOUSE; NONHUMAN; PARTICLE SIZE; PLASMID; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TUMOR CELL; VACCINATION;

ADSORPTION; ANIMALS; ANTIBODY FORMATION; BLOTTING, WESTERN; CATIONS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CETRIMONIUM COMPOUNDS; EXCIPIENTS; FEMALE; FLOW CYTOMETRY; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; IMMUNITY, CELLULAR; INTERFERON TYPE II; LACTIC ACID; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; NANOSTRUCTURES; PLASMIDS; POLYGLYCOLIC ACID; POLYMERS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VACCINES, DNA;

EID: 24944567410     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.06.020     Document Type: Article

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