Optimization of crystals of an inhibitory antibody of urokinase plasminogen activator receptor (uPAR) with hydrogen peroxide and low protein concentration

Protein and Peptide Letters

Volumn 12, Issue 7, 2005, Pages 655-658

  Li, Yongdong ^a   Shi, Xiaoli ^a   Parry, Graham ^b   Chen, Liqing ^c   Callahan, Jennifer A ^b   Mazar, Andrew P ^b   Huang, Mingdong ^a  

^a FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER   (China)

^b Attenuon LLC   (United States)

^c University of Alabama in Huntsville   (United States)

Author keywords

Antibody; Crystal optimization; Hydrogen peroxide; uPAR

Indexed keywords

ANTIBODY; CELL SURFACE RECEPTOR; HYDROGEN PEROXIDE; PLASMINOGEN ACTIVATOR, UROKINASE RECEPTORS;

ARTICLE; CHEMISTRY; CRYSTALLIZATION; DRUG ANTAGONISM; HUMAN; IMMUNOLOGY; METHODOLOGY; X RAY CRYSTALLOGRAPHY;

ANTIBODIES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN PEROXIDE; RECEPTORS, CELL SURFACE;

EID: 24944551386     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929866054696073     Document Type: Article

References (20)

1. Schubert, H. L., Raux, E., Warren, M. J. and Wilson, K. S. (2001) Acta Crystallogr. D. Biol. Crystallogr., 57, 867-9.
2. Kadirvelraj, R., Harris, P., Poulsen, J. C., Kauppinen, S. and Larsen, S. (2002) Acta Crystallogr. D. Biol. Crystallogr., 58, 1346-9.
3. Lartigue, A., Gruez, A., Briand, L., Pernollet, J. C., Spinelli, S., Tegoni, M. and Cambillau, C. (2003) Acta Crystallogr. D. Biol. Crystallogr., 59, 919-21.
4. Cudney, R. (1994) Acta Crystallogr. D. Biol. Crystallogr., 50, 414-23.
5. Stoppelli, M. P., Corti, A., Soffientini, A., Cassani, G., Blasi, F. and Assoian, R. K. (1985) Proc. Natl. Acad Sci. USA, 82, 4939-43.
6. Vassalli, J. D., Baccino, D. and Belin, D. (1985) J. Cell Biol., 100, 86-92.
7. Wei, Y., Waltz, D. A., Rao, N., Drummond, R. J., Rosenberg, S. and Chapman, H. A. (1994) J. Biol. Chem., 269, 32380-8.
8. Wei, Y., Lukashev, M., Simon, D. I., Bodary, S. C., Rosenberg, S., Doyle, M. V. and Chapman, H. A. (1996) Science, 273, 1551-5.
9. Simon, D. I., Wei, Y., Zhang, L., Rao, N. K., Xu, H., Chen, Z., Liu, Q., Rosenberg, S. and Chapman, H. A. (2000) J. Biol. Chem., 275, 10228-34.
10. Nguyen, D. H., Catling, A. D., Webb, D. J., Sankovic, M., Walker, L. A., Somlyo, A. V., Weber, M. J. and Gonias, S. L. (1999) J. Cell Biol., 146, 149-64.
11. Carriero, M. V., Del Vecchio, S., Capozzoli, M., Franco, P., Fontana, L., Zannetti, A., Botti, G., D'aiuto, G., Salvatore, M. and Stoppelli, M. P. (1999) Cancer Res., 59, 5307-14.
12. Wei, Y., Eble, J. A., Wang, Z., Kreidberg, J. A. and Chapman, H. A. (2001) Mol. Biol. Cell., 12, 2975-86.
13. Aguirre Ghiso, J. A., Alonso, D. F., Farias, E. F., Gomez, D. E. and De Kier Joffe, E. B. (1999) Eur. J. Biochem., 263, 295-304.
14. Mazar, A. P. (2001) Anticancer Drugs, 12, 387-400.
15. Ploug, M., Gardsvoll, H., Jorgensen, T. J., Lonborg Hansen, L. and Dano, K. (2002) Biochem. Soc. Trans., 30, 177-83.
16. Otwinowski, Z. and Minor, W., (1997) Methods Enzymol., 276, 307-26.
17. Carter, D. C., He, X. M., Munson, S. H., Twigg, P. D., Gernert, K. M., Broom, M. B. and Miller, T. Y. (1989) Science, 244, 1195-8.
18. Thomazeau, K., Curien, G., Thompson, A., Dumas, R. and Biou, V. (2001) Acta Crystallogr. D. Biol. Crystallogr., 57, 1337-40.
19. Kristensen, O., Laurberg, M. and Gajhede, M. (2002) Acta Crystallogr. D. Biol. Crystallogr., 58, 1198-200.
20. Dar, I., Bonny, C., Pedersen, J. T., Gajhede, M. and Kristensen, O. (2003) Acta Crystallogr. D. Biol. Crystallogr., 59, 2300-2.