Early steps in bilirubin-mediated apoptosis in murine hepatoma (Hepa 1c1c7) cells are characterized by aryl hydrocarbon receptor-independent oxidative stress and activation of the mitochondrial pathway

Journal of Biochemical and Molecular Toxicology

Volumn 19, Issue 4, 2005, Pages 244-255

  Oakes, Garth H ^a   Bend, John R ^a  

^a WESTERN UNIVERSITY   (Canada)

Author keywords

Aryl Hydrocarbon Receptor; Bilirubin; Caspase 2, 3, and 9; Glutathione; Hepa 1c1c7; Mitochondrial Membrane Potential; Oxidative stress

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BILIRUBIN; CARRIER PROTEIN; CASPASE 2; CASPASE 3; CASPASE 9; DYE; ENZYME PRECURSOR; GLUTATHIONE; HEME; PROCASPASE 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ASSAY; HEPATOMA CELL; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; APOPTOSIS; BILIRUBIN; CASPASES; CELL LINE, TUMOR; MICE; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION;

MURINAE;

EID: 24944549081     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.20086     Document Type: Article

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