Optical resolution by preferential crystallization of (1RS,3RS)-1,2,3,4- tetrahydro-6,7-dihydroxy-1-methyl-3-isoquinolinecarboxylic acid

Chemical and Pharmaceutical Bulletin

Volumn 53, Issue 9, 2005, Pages 1197-1199

  Shiraiwa, Tadashi ^a   Kiyoe, Ryuuichi ^a  

^a KANSAI UNIVERSITY   (Japan)

Author keywords

1,2,3,4 tetrahydroisoquinoline; Conglomerate; Optical resolution; Preferential crystallization

Indexed keywords

1,2,3,4 TETRAHYDRO 6,7 DIHYDROXY 1 METHYL 3 ISOQUINOLINECARBOXYLIC ACID; CARBOXYLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLIZATION; MELTING POINT; OPTICAL RESOLUTION; PURIFICATION; SOLUBILITY; SPECTROSCOPY; STRUCTURE ANALYSIS;

ALKALOIDS; CARBOXYLIC ACIDS; CRYSTALLIZATION; FREE RADICAL SCAVENGERS; ISOQUINOLINES; MAGNETIC RESONANCE SPECTROSCOPY; MUCUNA; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STEREOISOMERISM;

EID: 24944491199     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.53.1197     Document Type: Article

References (9)

1. Daxenbichler M. E., Kleiman R., Weisleder D., VanEtten C. H., Carlson K. D., Tetrahedron Lett., 18, 1801-1802 (1972).
2. Siddhuraju P., Becker K., J. Sci. Food Agr., 83, 1517-1524 (2003).
3. Dean R. T., Rapoport H., J. Org. Chem., 43, 4183-4189 (1978).
4. Brossi A., Focella A., Teitel S., Helv. Chim. Acta, 55, 15-21 (1972).
5. Bruderer H., Brossi A., Focella A., Teitel S., Helv. Chim. Acta, 58, 795-800 (1975).
6. Collet A., Brienne M. J., Jacques J., Chem. Rev., 80, 215-230 (1980).
7. Jacques J., Collet A., Wilen S. H., "Enantiomers, Racemates, and Resolutions," John Wiley and Sons, New York, 1981, pp. 217-241.
8. Shiraiwa T., Suzuki M., Sakai Y., Nagasawa H., Takatani K., Noshi D., Yamanashi K., Chem. Pharm. Bull., 50, 1362-1366 (2002).
9. Shiraiwa T., Saijoh R., Suzuki M., Yoshida K., Nishimura S., Nagasawa H., Chem. Pharm. Bull., 51, 1363-1367 (2003).