In vitro detection of differential and cell-specific hepatobiliary toxicity induced by geldanamycin and 17-allylaminogeldanamycin using dog liver slices

Toxicological Sciences

Volumn 87, Issue 2, 2005, Pages 442-450

  Amin, Khalid ^a   Ip, Carmen ^a   Jimenez, Lucita ^a   Tyson, Charles ^a   Behrsing, Holger ^a  

^a SRI INTERNATIONAL   (United States)

Author keywords

17 AAG; Dog; Geldanamycin; Liver slices; Toxicity

Indexed keywords

17 ALLYLAMINOGELDANAMYCIN; ALKALINE PHOSPHATASE; ANTINEOPLASTIC ANTIBIOTIC; GAMMA GLUTAMYLTRANSFERASE; GELDANAMYCIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL LOSS; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DOG; DRUG SENSITIVITY; EPITHELIUM CELL; HEPATOBILIARY SYSTEM; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CULTURE; LIVER NECROSIS; LIVER TOXICITY; NONHUMAN;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIMETABOLITES; BENZOQUINONES; BILIARY TRACT; BIOLOGICAL MARKERS; BROMODEOXYURIDINE; DOGS; HEPATITIS, TOXIC; IMMUNOHISTOCHEMISTRY; LACTAMS, MACROCYCLIC; LIVER; LIVER FUNCTION TESTS; QUINONES; RIFABUTIN;

CANIS FAMILIARIS;

EID: 24944469984     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi254     Document Type: Article

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