메뉴 건너뛰기




Volumn 72, Issue SPEC. ISS., 2005, Pages 51-57

Role of progesterone metabolites in mammary cancer

Author keywords

3 dihydroprogesterone; 5 dihydroprogesterone; 5 reductase; Cell adhesion; Cell proliferation; Hydroxysteroid oxidoreductases

Indexed keywords

20ALPHA HYDROXYSTEROID DEHYDROGENASE; 3 ALPHA HYDROXYSTEROID DEHYDROGENASE (B SPECIFIC); 3ALPHA HYDROXYSTEROID DEHYDROGENASE; MESSENGER RNA; PREGNANE DERIVATIVE; PROGESTERONE; STEROID 5ALPHA REDUCTASE;

EID: 24944469767     PISSN: 00220299     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0022029905001214     Document Type: Review
Times cited : (10)

References (46)
  • 2
    • 0030931653 scopus 로고    scopus 로고
    • Acute, nongenomic actions of the neuroactive gonadal steroid, 3α-hydroxy-4-pregnen-20-one (3αHP), on FSH release in perifused rat anterior pituitary cells
    • Beck CA, Wolfe M, Murphy LD & Wiebe JP 1997 Acute, nongenomic actions of the neuroactive gonadal steroid, 3α-hydroxy-4-pregnen-20-one (3αHP), on FSH release in perifused rat anterior pituitary cells. Endocrine 6 221-229
    • (1997) Endocrine , vol.6 , pp. 221-229
    • Beck, C.A.1    Wolfe, M.2    Murphy, L.D.3    Wiebe, J.P.4
  • 4
    • 0029553143 scopus 로고
    • Effect of progestin treatment on estradiol- and growth factor-stimulated breast cancer cell lines
    • Cappelletti V, Miodini P, Fiovaranti L & Di Fronzo G 1995 Effect of progestin treatment on estradiol- and growth factor-stimulated breast cancer cell lines. Anticancer Research 15 2551-2556
    • (1995) Anticancer Research , vol.15 , pp. 2551-2556
    • Cappelletti, V.1    Miodini, P.2    Fiovaranti, L.3    Di Fronzo, G.4
  • 5
    • 24944512479 scopus 로고    scopus 로고
    • Induced detachment of MCF-7 breast cancer cells by the progesterone metabolite, 5α-pregnane-3,20-dione, is linked to activation of the mitogen-activated protein kinase (Erk/MAPK) pathway
    • Cialacu V, Zhang G & Wiebe JP 2003 Induced detachment of MCF-7 breast cancer cells by the progesterone metabolite, 5α-pregnane-3,20-dione, is linked to activation of the mitogen-activated protein kinase (Erk/MAPK) pathway. Endocrine Society Annual Meeting Abstracts 85 P1, 138, p 166
    • (2003) Endocrine Society Annual Meeting Abstracts , vol.85
    • Cialacu, V.1    Zhang, G.2    Wiebe, J.P.3
  • 6
    • 0025293539 scopus 로고
    • Progestin regulation of cellular proliferation
    • Clark CL & Sutherland RL 1990 Progestin regulation of cellular proliferation. Endocrine Reviews 11 266-302
    • (1990) Endocrine Reviews , vol.11 , pp. 266-302
    • Clark, C.L.1    Sutherland, R.L.2
  • 8
    • 0025168534 scopus 로고
    • Cell proliferation in carcinogenesis
    • Cohen SM & Ellwein LB 1990 Cell proliferation in carcinogenesis. Science 249 1007-1011
    • (1990) Science , vol.249 , pp. 1007-1011
    • Cohen, S.M.1    Ellwein, L.B.2
  • 9
    • 0019816169 scopus 로고
    • Gross and histopathological effects of medroxyprogesterone acetate and progesterone on the mammary glands of adult beagle bitches
    • Concannon PW, Spraker TR, Casey HW & Hansel W 1981 Gross and histopathological effects of medroxyprogesterone acetate and progesterone on the mammary glands of adult beagle bitches. Fertility & Sterility 36 373-387
    • (1981) Fertility & Sterility , vol.36 , pp. 373-387
    • Concannon, P.W.1    Spraker, T.R.2    Casey, H.W.3    Hansel, W.4
  • 10
    • 0028084550 scopus 로고
    • Suppression of follicle-stimulating hormone by the gonadal- and neurosteroids 3α-hydroxy-4-pregnen-20-one involves actions at the level of the gonadotrope membrane/ calcium channel
    • Dhanvantari S & Wiebe JP 1994 Suppression of follicle-stimulating hormone by the gonadal- and neurosteroids 3α-hydroxy-4-pregnen-20-one involves actions at the level of the gonadotrope membrane/ calcium channel. Endocrinology 134 371-376
    • (1994) Endocrinology , vol.134 , pp. 371-376
    • Dhanvantari, S.1    Wiebe, J.P.2
  • 12
    • 0023867603 scopus 로고
    • Proliferative and secretory activity in human breast during natural and artificial menstrual cycles
    • Going JJ, Anderson TJ, Battersby S & MacIntyre CCA 1988 Proliferative and secretory activity in human breast during natural and artificial menstrual cycles. American Journal of Pathology 130 193-204
    • (1988) American Journal of Pathology , vol.130 , pp. 193-204
    • Going, J.J.1    Anderson, T.J.2    Battersby, S.3    MacIntyre, C.C.A.4
  • 14
    • 0016023048 scopus 로고
    • Comparative aspects of mammary tumors
    • (Eds G Klein, S Weinhouse & A Haddow). New York: Academic Press
    • Hamilton JM 1974 Comparative aspects of mammary tumors. In Advances in Cancer Research, pp. 1-45. (Eds G Klein, S Weinhouse & A Haddow). New York: Academic Press
    • (1974) Advances in Cancer Research , pp. 1-45
    • Hamilton, J.M.1
  • 16
    • 0346996801 scopus 로고    scopus 로고
    • Progesterone involvement in breast development and tumorigenesis - As revealed by progesterone receptor "knockout" and "knockin" mouse models
    • Ismail PM, Amato P, Soyal SM, DeMayo FJ, Conneely OM, O'Malley BW & Lydon JP 2003 Progesterone involvement in breast development and tumorigenesis - as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids 68:779-787.
    • (2003) Steroids , vol.68 , pp. 779-787
    • Ismail, P.M.1    Amato, P.2    Soyal, S.M.3    Demayo, F.J.4    Conneely, O.M.5    O'Malley, B.W.6    Lydon, J.P.7
  • 17
    • 0014099063 scopus 로고
    • Effects of progesterone on 9,10-dimethyl-1,2-benzanthracene-induced mammary tumours in Sprague-Dawley rats
    • Jabara AG 1967 Effects of progesterone on 9,10-dimethyl-1,2- benzanthracene-induced mammary tumours in Sprague-Dawley rats. British Journal of Cancer 21 418-429
    • (1967) British Journal of Cancer , vol.21 , pp. 418-429
    • Jabara, A.G.1
  • 19
    • 0026012317 scopus 로고
    • A discussion of the role of estrogen and progestin in human mammary carcinogenesis
    • King RJB 1991 A discussion of the role of estrogen and progestin in human mammary carcinogenesis. Journal of Steroid Biochemistry & Molecular Biology 39 811-818
    • (1991) Journal of Steroid Biochemistry & Molecular Biology , vol.39 , pp. 811-818
    • King, R.J.B.1
  • 20
    • 0036438977 scopus 로고    scopus 로고
    • Progesterone receptors-animal models and cell signaling in breast cancer. Diverse activation pathways for the progesterone receptor: Possible implications for breast biology and cancer
    • Lanari C & Molinolo AA 2002 Progesterone receptors-animal models and cell signaling in breast cancer. Diverse activation pathways for the progesterone receptor: possible implications for breast biology and cancer. Breast Cancer Research 4 240-243
    • (2002) Breast Cancer Research , vol.4 , pp. 240-243
    • Lanari, C.1    Molinolo, A.A.2
  • 21
    • 5644274754 scopus 로고    scopus 로고
    • Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma
    • Lewis MJ, Wiebe JP & Heathcote JG 2004 Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma. BMC Cancer 4 27 (pp 1-12) (http://www.biomedcentral. com/1471-2407/4/27)
    • (2004) BMC Cancer , vol.4 , pp. 27
    • Lewis, M.J.1    Wiebe, J.P.2    Heathcote, J.G.3
  • 22
    • 0031437691 scopus 로고    scopus 로고
    • Inhibitory effect of the novel anti-estrogen EM-800 and medroxyprogesterone acetate on estrone-stimulated growth of dimethylbenz[a] anthracene-induced mammary carcinoma in rats
    • Luo S, Stojanovic M & Labrie F 1997 Inhibitory effect of the novel anti-estrogen EM-800 and medroxyprogesterone acetate on estrone-stimulated growth of dimethylbenz[a]anthracene-induced mammary carcinoma in rats. International Journal of Cancer 73 580-586
    • (1997) International Journal of Cancer , vol.73 , pp. 580-586
    • Luo, S.1    Stojanovic, M.2    Labrie, F.3
  • 24
    • 0029876940 scopus 로고    scopus 로고
    • New insights in the molecular mechanism of progestin-induced proliferation of mammary epithelium: Induction of the local biosynthesis of growth hormone (GH) in the mammary gland of dogs, cats and humans
    • Mol JA, van Garderen E, Rutteman GR & Rijnberk A 1996 New insights in the molecular mechanism of progestin-induced proliferation of mammary epithelium: induction of the local biosynthesis of growth hormone (GH) in the mammary gland of dogs, cats and humans. Journal of Steroid Biochemistry & Molecular Biology 57 67-71
    • (1996) Journal of Steroid Biochemistry & Molecular Biology , vol.57 , pp. 67-71
    • Mol, J.A.1    Van Garderen, E.2    Rutteman, G.R.3    Rijnberk, A.4
  • 26
    • 0018571642 scopus 로고
    • A comparative study of canine and human breast cancer
    • Owen LN 1979 A comparative study of canine and human breast cancer. Investigative and Cell Pathology 2 257-275
    • (1979) Investigative and Cell Pathology , vol.2 , pp. 257-275
    • Owen, L.N.1
  • 27
    • 18044383617 scopus 로고    scopus 로고
    • Plasma membrane receptors for the cancer-promoting progesterone metabolite, 5α-pregnane-3,20-dione, are modulated by other endogenous steroid hormones
    • Pawlak KJ & Wiebe JP 2003 Plasma membrane receptors for the cancer-promoting progesterone metabolite, 5α-pregnane-3,20-dione, are modulated by other endogenous steroid hormones. Endocrine Society Annual Meeting Abstracts 85 P1, 136, p166
    • (2003) Endocrine Society Annual Meeting Abstracts , vol.85
    • Pawlak, K.J.1    Wiebe, J.P.2
  • 29
    • 0027304028 scopus 로고
    • Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk
    • Pike MC, Spicer DV, Dahmoush L & Press MF 1993 Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk. Epidemiologic Reviews 15 17-35
    • (1993) Epidemiologic Reviews , vol.15 , pp. 17-35
    • Pike, M.C.1    Spicer, D.V.2    Dahmoush, L.3    Press, M.F.4
  • 30
    • 0024199652 scopus 로고
    • Adhesive properties of metastasizing tumor cells
    • Raz A 1988 Adhesive properties of metastasizing tumor cells. Ciba Foundation Symposium 141 109-122
    • (1988) Ciba Foundation Symposium , vol.141 , pp. 109-122
    • Raz, A.1
  • 36
    • 0028377095 scopus 로고
    • Mammary tumorigenesis and metastasis in transgenic mice
    • Webster MA & Muller WJ 1994 Mammary tumorigenesis and metastasis in transgenic mice. Seminars in Cancer Biology 5 69-76
    • (1994) Seminars in Cancer Biology , vol.5 , pp. 69-76
    • Webster, M.A.1    Muller, W.J.2
  • 37
    • 0034674243 scopus 로고    scopus 로고
    • Plasma membrane receptors for the cancer-regulating progesterone metabolites, 5α-pregnane-3,20-dione and 3α-hydroxy-4-pregnen-20-one in MCF-7 breast cancer cells
    • Weiler PJ & Wiebe JP 2000 Plasma membrane receptors for the cancer-regulating progesterone metabolites, 5α-pregnane-3,20-dione and 3α-hydroxy-4-pregnen-20-one in MCF-7 breast cancer cells. Biochemical and Biophysical Research Communications 272 731-737
    • (2000) Biochemical and Biophysical Research Communications , vol.272 , pp. 731-737
    • Weiler, P.J.1    Wiebe, J.P.2
  • 38
    • 0013484080 scopus 로고
    • Hormones and murine mammary tumorigenesis: An historical view
    • (Ed. BS Leung). Montreal, Canada: Eden Press
    • Welsh CW 1982 Hormones and murine mammary tumorigenesis: an historical view. In: Hormonal Regulation of Mammary Tumors, pp. 1-29 (Ed. BS Leung). Montreal, Canada: Eden Press
    • (1982) Hormonal Regulation of Mammary Tumors , pp. 1-29
    • Welsh, C.W.1
  • 39
    • 0030627816 scopus 로고    scopus 로고
    • Nongenomic actions of steroids on gonadotropin release
    • Wiebe JP 1997 Nongenomic actions of steroids on gonadotropin release. Recent Progress in Hormone Research 52 71-101
    • (1997) Recent Progress in Hormone Research , vol.52 , pp. 71-101
    • Wiebe, J.P.1
  • 40
    • 0035663921 scopus 로고    scopus 로고
    • The endogenous progesterone metabolite, 5α-pregnene-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells
    • Wiebe JP & Muzia D 2001 The endogenous progesterone metabolite, 5α-pregnene-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine 16 7-14
    • (2001) Endocrine , vol.16 , pp. 7-14
    • Wiebe, J.P.1    Muzia, D.2
  • 41
    • 3042716504 scopus 로고    scopus 로고
    • Activity and expression of progesterone metabolizing 5α-reductase, 20α-hydroxysteroid oxidoreductase and 3α(β)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells
    • Wiebe JP & Lewis MJ 2003 Activity and expression of progesterone metabolizing 5α-reductase, 20α-hydroxysteroid oxidoreductase and 3α(β)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells. BMC Cancer 3 (pp. 1-15) (http://www.biomedcentral.com/1471-2407/3/9)
    • (2003) BMC Cancer , vol.3 , pp. 1-15
    • Wiebe, J.P.1    Lewis, M.J.2
  • 42
    • 0023095011 scopus 로고
    • Modification of steroidogenesis in rat adrenocortical cells transformed by Kirsten Murine Sarcoma virus
    • Wiebe JP, Myers KI & Auersperg N 1987 Modification of steroidogenesis in rat adrenocortical cells transformed by Kirsten Murine Sarcoma virus. Cancer Research 47 1325-1332
    • (1987) Cancer Research , vol.47 , pp. 1325-1332
    • Wiebe, J.P.1    Myers, K.I.2    Auersperg, N.3
  • 43
    • 0030757791 scopus 로고    scopus 로고
    • Synthesis, metabolism and levels of the neuroactive steroid, 3α-hydroxy-4-pregnen-20-one (3αHP), in rat pituitaries
    • Wiebe JP, Boushy D & Wolfe M 1997 Synthesis, metabolism and levels of the neuroactive steroid, 3α-hydroxy-4-pregnen-20-one (3αHP), in rat pituitaries. Brain Research 764 158-166
    • (1997) Brain Research , vol.764 , pp. 158-166
    • Wiebe, J.P.1    Boushy, D.2    Wolfe, M.3
  • 45
    • 0028006239 scopus 로고
    • Suppression in gonadotropes of gonadotropin-releasing hormone-stimulated follicle-stimulating hormone release by the gonadal- and neurosteroid 3α-hydroxy-4-pregnen-20-one involves cytosolic calcium
    • Wiebe JP, Dhanvantari S, Watson PH & Huang Y 1994 Suppression in gonadotropes of gonadotropin-releasing hormone-stimulated follicle-stimulating hormone release by the gonadal- and neurosteroid 3α-hydroxy-4-pregnen-20- one involves cytosolic calcium. Endocrinology 134 377-382
    • (1994) Endocrinology , vol.134 , pp. 377-382
    • Wiebe, J.P.1    Dhanvantari, S.2    Watson, P.H.3    Huang, Y.4
  • 46
    • 0034651239 scopus 로고    scopus 로고
    • The 4-pregnene and 5α-pregnane progesterone metabolites formed in non-tumorous and tumorous breast tissue have opposite effects on breast cell proliferation and adhesion
    • Wiebe JP, Muzia D, Hu J, Szwajcer D, Hill SA & Seachrist JL 2000 The 4-pregnene and 5α-pregnane progesterone metabolites formed in non-tumorous and tumorous breast tissue have opposite effects on breast cell proliferation and adhesion. Cancer Research 60 936-943
    • (2000) Cancer Research , vol.60 , pp. 936-943
    • Wiebe, J.P.1    Muzia, D.2    Hu, J.3    Szwajcer, D.4    Hill, S.A.5    Seachrist, J.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.