Expression of glucocorticoid receptors in nephrotic children depending on total prednisone dose

Journal of Pediatric Endocrinology and Metabolism

Volumn 18, Issue 8, 2005, Pages 799-806

  Wasilewska, Anna ^a   Zoch Zwierz, Walentyna ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

CD14 GCR; CD3 GCR; Lymphocytes; Monocytes; Nephrotic syndrome

Indexed keywords

CD14 ANTIGEN; CD3 ANTIGEN; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; PREDNISONE;

ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DOSE RESPONSE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; MONOCYTE; NEPHROTIC SYNDROME; PERIPHERAL LYMPHOCYTE; PROTEINURIA; RECEPTOR UPREGULATION; TREATMENT OUTCOME;

EID: 24944446110     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2005.18.8.799     Document Type: Article

References (27)

1. Griese M, Kusenbach G, Lusebring K, Koster W, Roth B, Reinhardt D. Glucocorticoid receptors in mononuclear blood cells and their correlation to endogenous and exogenous corticoids in healthy and asthmatic children. Eur J Pediatr 1998; 147: 490-495.
2. Spahn JD, Landwehr LP, Nimmagadda S, Surs W, Leung DYM, Szefler SJ. Effects of glucocorticoids on lymphocyte activation in patients with steroid-sensitive and steroid-resistant asthma. J Allergy Clin Immunol 1996; 98: 1073-1079.
3. Bagdasorova IV, Ivanov DD, Afanaseva VV. The morphofunctional characteristics of the blood lymphocytes in steroid-sensitive and steroid-resistant glomerulonephritis. Arkh Pathol 1991; 53: 28-32.
4. DeRijk R, Sternberg EM. Corticosteroid resistance and disease. Ann Med 1997; 29: 79-82.
5. Kaspers GJL, Pieters R, Klumper E, De Waal FC, Veerman AJP. Glucocorticoid resistance in childhood leukemia. Leuk Lymphoma 1994; 13: 187-201.
6. Shimada T, Hiwataschi N, Yamazaki H, Kinouchi Y, Toyota T. Relationship between glucocorticoid receptor and response to glucocorticoid therapy in ulcerative colitis. Dis Colon Rectum 1997; 40: S54-S58.
7. Rogler G, Meinel A, Lingauer A, Michl J, Zietz B, Gross V, Lang B, Andus T, Scholmerich J, Palitzsch KD. Glucocorticoid receptors are down-regulated in inflamed colonic mucosa but not in peripheral blood mononuclear cells from patients with inflammatory bowel disease. Eur J Clin Invest 1999; 29: 330-336.
8. Schottelius A, Wedel S, Weltrich R, Rohde W, Buttgereit F, Schreiber S, Lochs H. Higher expression of glucocorticoid receptor in peripheral mononuclear cells in inflammatory bowel diseases. AJG 2000; 95: 1994-1999.
9. Haack D, Scharer K, Asam-Tauscher A, Vecsei P. Glucocorticoid receptors in idiopathic nephrotic syndrome. Pediatr Nephrol 1999; 13: 653-656.
10. Wasilewska A, Zoch-Zwierz W, Tomaszewska B, Wierciński R, Stasiak-Barmuta A. Expression of glucocorticoid receptors in mononuclear cells in nephrotic syndrome. Pediatr Nephrol 2003; 18: 778-782.
11. Grzanka A, Jarzab J, Rogala B. Molecular mechanism of glucocorticoid action. Pol Arch Med Wewn 1996; 95: 375-382.
12. Berki T, Grama L, Nemeth P. Detection of steroid induced glucocorticoid receptor (GCR) translocation and expression with a FITC labelled monoclonal antibody. Cytometry Suppl 2000; 10: 99-102.
13. Tanaka H, Akama H, Ichikawa Y, Makino I, Homma M. Glucocorticoid receptor in patients with lupus nephritis: relationship between receptor levels in mononuclear leucocytes and effect of glucocorticoid therapy. J Rheumatol 1992; 19: 878-883.
14. Lindberg C, Jonsson S, Hedner P, Gustafsson A. Radioimmunoassay and chemical ionization/mass spectrometry compared for plasma cortisol determination. Clin Chem 1982; 28: 174-177.
15. Farrel RJ, Kelleher D. Glucocorticoid resistance in inflammatory bowel disease. J Endocrinol 2003; 178: 339-346.
16. Shipman GF, Bloomfield CD, Kazimiera JGP, Munck AU, Smirt KA. Glucocorticoids and lymphocytes. III. Effects of glucocorticoid administration on lymphocyte glucocorticoid receptor. Blood 1983; 61: 1086-1090.
17. Tanaka H, Akama H, Ichikawa Y, Homma M, Oshima H. Glucocorticoid receptors in normal leukocytes: effects of age, gender, season, and plasma cortisol concentrations. Clin Chem 1997; 37: 1715-1719.
18. Dakley RH, Cidlowski JA. Homologous down regulation of glucocorticoid receptor: the molecular machinery. Crit Rev Eukaryot Gene Expr 1993; 3: 63-67.
19. Lowy MT. Corticosterone regulation of brain and lymphoid corticosteroid receptors. J Steroid Biochem Mol Biol 1991; 39: 147-151.
20. DiBattista JA, Martel-Pelletier J, Coultier JM, Pelletier JP. Modulation of glucocorticoid receptor expression in human artricular chondrocytes by cAMP and prostaglandins. J Rheumatol 1991; 27: 102-105.
21. Salkowski CA, Vogel SN. INF-gamma mediates increased glucocorticoid receptor expression in murine macrophages. J Immunol 1992; 14: 2770-2773.
22. Crabtree GR, Munck A, Smith KA. Glucocorticoids and lymphocytes. J Immunol 1980; 125: 13-16.
23. Berki T, Kumanovics G, Kumanowics A, Falus A, Ujhelyi E, Nemeth P. Production and flow cytometric application of a monoclonal anti-glucocorticoid receptor antibody. J Immunol Meth 1998; 214: 19-27.
24. Berki T, Tavakoli A, Nagy KK, Nagy G, Nemeth P. Alterations of glucocorticoid receptor expression during glucocorticoid hormone therapy in renal transplant patients. Transplant Int 2002; 15: 132-138.
25. Sanden S, Tripmacher R, Weltrich R, Rohde W, Hiepe F, Burmester GR, Buttgereit F. Glucocorticoid dose dependent downregulation of glucocorticoid receptors in patients with rheumatic diseases. J Rheumatol 2000; 27: 1265-1270.
26. Carvalho AP, Franco PB, Elias LL, Facincania I, Costa EL, Foss N, Moreira AC, Castro M. Glucocorticoid receptors, in vitro steroid sensitivity, and cytokine secretion in idiopathic nephrotic syndrome. Kidney Int 2004; 65: 403-406.
27. Andreae J, Tripmacher R, Weltrich R, Rohde W, Keitzer R, Wahn U, Paul K, Buttgereit F. Effect of glucocorticoid therapy on glucocorticoid receptors in children with autoimmune diseases. Pediatr Res 2001; 49: 130-135.