Rapid inhibition of MAPK signaling and anti-proliferation effect via JAK/STAT signaling by interferon-α in hepatocellular carcinoma cell lines

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1745, Issue 3, 2005, Pages 401-410

  Inamura, Kentaro ^a   Matsuzaki, Yasushi ^a   Uematsu, Naoya ^a   Honda, Akira ^a   Tanaka, Naomi ^a   Uchida, Kazuhiko ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Extracellular signal regulated kinase (ERK); Interferon (IFN); Janus kinase1 (JAK1); Mitogen activated ERK regulating kinase (MEK); Signal transducers of activation and transcription1 (STAT1); Small interfering RNA (siRNA)

Indexed keywords

ALPHA INTERFERON; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; STAT PROTEIN;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; ENZYME REGULATION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTERFERON-ALPHA; JANUS KINASE 1; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; STAT1 TRANSCRIPTION FACTOR;

EID: 24944444235     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2005.06.003     Document Type: Article

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