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Volumn 61, Issue 42, 2005, Pages 10048-10060

Synthesis of some oligopyridine-galactose conjugates and their metal complexes: A simple entry to multivalent sugar ligands

Author keywords

Carbohydrates; Metal complexes; N ligand

Indexed keywords

BIPYRIDINE DERIVATIVE; COPPER DERIVATIVE; GALACTOSE; LIGAND; METAL COMPLEX; PYRIDINE DERIVATIVE; SUGAR; ZINC DERIVATIVE;

EID: 24944435479     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2005.08.018     Document Type: Article
Times cited : (19)

References (28)
  • 2
    • 0037905565 scopus 로고    scopus 로고
    • The Chemistry and Biology of Multivalent Saccharide Displays
    • P.G. Wang C.R. Bertozzi Marcel Dekker
    • D.A. Mann, and L.L. Kiessling The Chemistry and Biology of Multivalent Saccharide Displays P.G. Wang C.R. Bertozzi Glycochemistry - Principles, Synthesis, and Applications 2001 Marcel Dekker 221 275
    • (2001) Glycochemistry - Principles, Synthesis, and Applications , pp. 221-275
    • Mann, D.A.1    Kiessling, L.L.2
  • 19
    • 0000820721 scopus 로고    scopus 로고
    • It must be noted that ligand 14 contains two additional nitrogen atoms as potentially competing binding sites for Cu(I). It has been shown however, that the imine nitrogens of some imine-bridged olygobipyridine ligands were not involved in the complexation with Cu(I) cations, that occurred exclusively at the bipyridine nitrogens. On the basis of NMR evidence we believe that this is also the case for the complexation of ligand 14. For a leading reference see: R. Stiller, and J.-M. Lehn Eur. J. Inorg. Chem. 1998 977 982
    • (1998) Eur. J. Inorg. Chem. , pp. 977-982
    • Stiller, R.1    Lehn, J.-M.2
  • 23
    • 24944526064 scopus 로고    scopus 로고
    • note
    • Compounds 16-19 were scarcely soluble in MeOH and reasonably soluble in DMSO, that was the only solvent for ligand 20. Analytically pure samples of 16-20 could not be obtained.
  • 24
    • 24944517319 scopus 로고    scopus 로고
    • note
    • Attempts of running the complexation reaction of 16-20 in DMSO met with no success, probably because of the strongly coordinating nature of this solvent.
  • 25
    • 24944436564 scopus 로고    scopus 로고
    • note
    • 3OD. When the NMR spectra of these complexes were recorded in DMSO extensive complex decomposition was observed. As in the case of the polyols, from which they formally derive, isolation of analytically pure compounds was not possible. These solubility properties may represent a problem in the biological studies of such a compounds. Studies are currently underway in order to solve this problem.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.